Results 171 to 180 of about 17,248,582 (189)

Influence of maltodextrin on meloxicam solubility in water and biorelevant media

Poorly soluble drugs are characterized by their limited solubility in aqueous media which affects their bioavailability, absorption efficiency, and ultimately their therapeutic potential. More than 70 % of molecules that are candidates for new drugs exhibit low water solubility, while 40 % of orally administered drugs with immediate release are ...
Galić, Nives, Pocrnić, Marijana, Remar, Karla   +2 more
openaire  

A thermodynamic approach for predicting thermodynamic phase behaviors of pharmaceuticals in biorelevant media

Chemical Engineering Science, 2022
Yuanhui Ji
exaly  

Update on Gastrointestinal Biorelevant Media and Physiologically Relevant Dissolution Conditions

Dissolution Technologies, 2022
Daniela Amaral Silva, Neal M. Davies, Nadia Bou-Chacra, Humberto Gomes Ferraz, Raimar Löbenberg   +4 more
openaire   +1 more source

Evaluation of biorelevant dissolution media simulating fasted and fed states

2018
The most important criteria for evaluating in vitro performance and in vivo behavior of drugs is dissolution tests. It is necessary to provide conditions that best mimic the in vivo media in dissolution tests. The most important condition is the dissolution media used.
Yaşin, Diren Sarısaltık, Teksi̇n, Zeynep Şafak   +1 more
openaire   +1 more source

Nanozeolites and their analytical use as chemosensors in biorelevant media

2022
BIEDERMANN FRANK, GRIMM LAURA, SINN STEPHAN   +2 more
openaire   +3 more sources

Similarity of dissolution profiles from biorelevant media: Assessment of interday repeatability, interanalyst repeatability, and interlaboratory reproducibility using ibuprofen and ketoconazole tablets

European Journal of Pharmaceutical Sciences, 2021
Harsh Shah, James E Polli, Kajal Nahar
exaly  

Biorelevant Dissolution Media

2007
openaire   +1 more source

A novel theoretical strategy for predicting dissolution kinetics and mechanisms of pharmaceuticals in complex biorelevant media

International Journal of Pharmaceutics, 2023
Yuanhui Ji, Gabriele Sadowski, Raphaël Paus   +2 more
exaly  

Characterising the behaviour of poorly water soluble drugs in the intestine: application of biorelevant media for solubility, dissolution and transport studies.

Journal of Pharmacy and Pharmacology, 2010
Jette Bredahl Jacobsen, Anette Müllertz, Karen Kleberg   +2 more
exaly  

Use of biorelevant media for assessment of a poorly soluble weakly basic drug in the form of liquisolid compacts: in vitro and in vivo study

Drug Delivery, 2016
Amany Kamel
exaly