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Update on Gastrointestinal Biorelevant Media and Physiologically Relevant Dissolution Conditions
Dissolution Technologies, 2022Daniela Amaral Silva +4 more
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Theoretical modeling and prediction of biorelevant solubility of poorly soluble pharmaceuticals
Chemical Engineering Journal, 2022kai ge, Gabriele Sadowski, Yuanhui Ji
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Evaluation of biorelevant dissolution media simulating fasted and fed states
The most important criteria for evaluating in vitro performance and in vivo behavior of drugs is dissolution tests. It is necessary to provide conditions that best mimic the in vivo media in dissolution tests. The most important condition is the dissolution media used.Yaşin, Diren Sarısaltık +1 more
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Designing biorelevant media to simulate postprandial gastric conditions in infants
International Journal of Pharmaceutics, 2016Elisabeth Kersten, Sandra Klein
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Influence of maltodextrin on meloxicam solubility in water and biorelevant media
Poorly soluble drugs are characterized by their limited solubility in aqueous media which affects their bioavailability, absorption efficiency, and ultimately their therapeutic potential. More than 70 % of molecules that are candidates for new drugs exhibit low water solubility, while 40 % of orally administered drugs with immediate release are ...Galić, Nives, Pocrnić, Marijana
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