Results 161 to 170 of about 2,382,076 (302)

E3 ligase Praja1 mediates ubiquitination and degradation of microtubule‐associated protein tau

open access: yesThe FEBS Journal, EarlyView.
E3 ligase Praja1, but not its paralogue Praja2, recognizes and ubiquitinates tau protein for proteasomal degradation. This newly identified function of Praja1‐mediated tau degradation suggests its role in protein quality control, which may provide insights into the pathogenesis of tauopathies.
Shiho Aoki   +8 more
wiley   +1 more source

Search for medicinal plants with pharmaceutical use by integration of the physical and biotic informations in a geographic information system: The interface steppe region - Saharan region (Algeria) [PDF]

open access: yes, 2015
Algeria is a large, rich country in flora and fauna. The objective of this study was the integration of biological and physical data in a GIS for research of medicinal plants.Postprint (published ...
Bousmaha, A.M.   +8 more
core   +1 more source

The ibasu-a collection of algal strains as bioresources for biodiesel production

open access: yes, 2014
The growth characteristics and productivity of strains from the Microalgal Culture Collection IBASU-A were analyzed and some perspective high biomass producers were selected in the separated culture collection which considered as potential bioresource of feedstock for biodiesel production.
Tsarenko, P., Borysova, E.
openaire   +1 more source

Oxygen‐independent expression of HIF‐1α during the cell cycle in hepatocellular carcinoma cells controls essential metabolic pathways under normoxia

open access: yesThe FEBS Journal, EarlyView.
In Huh7 cells, HIF‐1α is essential as it maintains the expression of proteins involved in glycolysis and steroid/cholesterol biosynthesis both under normoxia and hypoxia. On the other hand, in HeLa cells, these pathways are induced by HIF‐1α only under hypoxia.
Ioanna‐Maria Gkotinakou   +6 more
wiley   +1 more source

Modeling and analyzing the agroecological performance of farms with ECOPATH [PDF]

open access: yes
Intensive and integrated resource management, where field crops, vegetables, trees, livestock and fish production are combined through efficient reuse of wastes, residues, by-products and external inputs, offers a potential avenue towards a productive ...
Dalsgaard, J.P.T., Oficial, R.T.
core  

Anemia‐associated mutations disrupt the CDIN1‐Codanin1 complex in inherited congenital dyserythropoietic anemia I (CDA‐I) disease

open access: yesThe FEBS Journal, EarlyView.
Congenital dyserythropoietic anemia type I (CDA‐I) arises from mutations in Codanin1 and CDIN1. Using quantitative biophysical approaches, we show that disease‐associated mutations disrupt the CDIN1‐Codanin1 complex. Our findings provide critical insights into the molecular mechanism that links protein dysfunction to disturbing chromatin arrangement ...
Martin Stojaspal   +8 more
wiley   +1 more source

Aquaculture policy options for integrated resource management in SubSaharan Africa: extended abstracts and discussions [PDF]

open access: yes
This volume contains brief papers which review the socioeconomic and biophysical environment in which integrated aquaculture must function in subSaharan Africa; presentations of experiences from research and the field, including both biotechnical and ...
Brummet, R.E. (ed.)
core  

RNA‐Seq analysis revealed differentially expressed genes linked to seed size variation in sainfoin

open access: yesGrassland Science, EarlyView.
Abstract Sainfoin is a perennial forage legume with many desirable characteristics such as easy to establish, bloat‐free trait for grazing ruminants and providing pollinator habitat and biological nitrogen fixation to soil. However, adoption of this species is often hindered by high seed cost associated with its larger seed size compared to other ...
Surendra Bhattarai   +3 more
wiley   +1 more source

Sacubitril/Valsartan Attenuates Inflammation and Fibrosis Associated With Decreased Integrin α8 and Inhibits Hepatocarcinogenesis in a Rat Model of Metabolic Dysfunction‐Associated Steatohepatitis

open access: yesHepatology Research, EarlyView.
Sacubitril/Valsartan (Sac/Val) alleviates fibrosis and inflammation in metabolic dysfunction‐associated steatohepatitis (MASH). Its anti‐fibrotic effect is linked to the suppression of Integrin alpha 8 (Itga8), a protein crucial for hepatic stellate cell (HSC) activation and collagen production.
Hayato Kawamura   +11 more
wiley   +1 more source

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