Results 171 to 180 of about 50,173 (296)

Integrative Phosphoproteomic Profiling Reveals Stage‐Specific Signalling and Metabolism in Equine Melanocytic Neoplasm

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Equine melanocytic neoplasms (EMN) are aggressive tumours characterised by high metastatic potential and limited therapeutic options available. However, the molecular mechanisms underlying their progression remain poorly understood. This study therefore presents the integrative phosphoproteomic analysis of EMN tissue, with the aim of ...
Paitoon Srimontri, Amornthep Kingkaw, Nawarus Prapaiwan, Rangsima Sujittosakul, Nichapat Iamkaewprasert, Jiraschaya Piputwat, Puetta Isama‐al, Thanutchanok Munkongdee, Thanapon Chotikaprakal, Petchpailin Yanyongsirikarn, Narumon Phaonakrop, Sittiruk Roytrakul, Wanwipa Vongsangnak, Parichart Tesena   +13 more
wiley   +1 more source

Integrating genetics, age and imaging to predict treatment outcomes in neovascular age-related macular degeneration: a proof-of-concept study. [PDF]

Sci Rep
Moghul I, Pontikos N, Sharma A, Liu T, Soomro T, Wagner SK, Silva AS, Zhang G, Naik G, Bagga P, Chan YW, Keane PA, Cipriani V, Sivaprasad S, Webster AR, Balaskas K.   +15 more
europepmc   +1 more source

Hyperthermia‐induced cytotoxicity and modulation of PD‐L1 and MHC‐I expression in human non‐small cell lung cancer cell lines

Experimental Physiology, EarlyView.
Abstract Hyperthermia has recently been applied to treat human non‐small cell lung cancer (NSCLC). However, the mechanisms underlying cytotoxic sensitivity of NSCLC cells to hyperthermia are not fully understood. In this study, five NSCLC cell lines with different epidermal growth factor receptor (EGFR), Kirsten rat sarcoma and tumor protein p53 ...
Yun‐Chieh Tu, Wei‐Chen Yeh, Yi‐Wei Fang, Ko‐Hsuan Lo, Lei‐Ni Liang, Xu‐Chen Liu, Chia‐Chi Tsai, Chih‐Cheng Cheng, Meng‐Chieh Lin, Hsin‐Hsien Yu, Bor‐Chyuan Su   +10 more
wiley   +1 more source

First record of the complete mitochondrial genome of <i>Streblote castanea</i> (Swinhoe, 1892) (Lepidoptera: Lasiocampidae). [PDF]

Mitochondrial DNA B Resour
Wang HW, Wang X, Guo FY, Zhu HT, Li SY, Zhou X.   +5 more
europepmc   +1 more source

A high‐fat, high‐sugar diet impairs maternal metabolism throughout pregnancy and lactation in mice

The Journal of Physiology, EarlyView.
Abstract figure legend This study examined the impact of a high‐fat, high‐sugar (HFHS) diet consumed before mating and throughout pregnancy and lactation on maternal metabolic adaptation and early offspring outcomes in mice. Compared with controls, HFHS‐fed dams showed greater adiposity, impaired glucose tolerance, altered fuel utilisation with higher ...
Stephanie E. O'Hara, Kelly M. Gembus, Georgia S. Clarke, Amanda J. Page, Kathryn L. Gatford, Lisa M. Nicholas   +5 more
wiley   +1 more source

Overexpression of placenta-specific noncanonical imprinted genes causes placental enlargement in intersubspecific hybrid mice†. [PDF]

Biol Reprod
Tokita S, Watanabe N, Hasegawa A, Funaya S, Miura K, Matoba S, Ogura A, Inoue K.   +7 more
europepmc   +1 more source

Metabolome analysis identified exogenous cholesterol within lipid rafts that activate the Akt/mTOR signaling pathway in epithelial ovarian cancer

International Journal of Cancer, Volume 159, Issue 1, Page 257-268, 1 July 2026.
What's New? Epithelial ovarian cancer (EOC) is a severe malignancy with few effective treatment options. While the mechanisms remain unclear, changes in lipid metabolism may fuel tumor growth and EOC progression, offering a possible path for new treatments.
Hitomi Sakaguchi‐Mukaida, Kosuke Hiramatsu, Tatsuo Masuda, Mamoru Kakuda, Satoshi Nakagawa, Tadashi Iwamiya, Shinya Matsuzaki, Tetsuji Naka, Yutaka Ueda, Tadashi Kimura, Michiko Kodama   +10 more
wiley   +1 more source

Complete genome sequence of Oscillospiraceae bacterium MB24-C1, isolated from sewage sludge. [PDF]

Microbiol Resour Announc
Zhao J, Qiu W, Li F, Dong G, Li Y, Shih C-J, Wu Y-C, Wu C-H, Lai S-J, Xiao W, Zhang W-L, Li N, Chen S-C.   +12 more
europepmc   +1 more source

DYNAMICS OF EGG PRODUCTION IN CHICKENS OF VARIOUS BREEDS OF BIORESOURCE COLLECTIONS

Polythematic Online Scientific Journal of Kuban State Agrarian University, 2018
O. V. Mitrofanova, N. V. Dementeva
openaire   +1 more source

Single versus repeated intravenous oncolytic reovirus infusions: Implications for immune modulation and rationalised scheduling of therapy in hepatocellular carcinoma

International Journal of Cancer, Volume 158, Issue 12, Page 3252-3267, 15 June 2026.
What's new? Oncolytic viruses are a promising immunotherapeutic approach against many malignancies. However, it is unclear whether repeated doses have improved therapeutic value or may trigger greater side effects, especially in patients with hepatocellular carcinoma whose liver is chronically damaged.
Karen J. Scott, Emma J. West, Rebecca J. Brownlie, Fay Ismail, Christy Ralph, Thomas Heineman, Matt Coffey, Alan A. Melcher, Alison Taylor, Salvatore Papa, Adel Samson   +10 more
wiley   +1 more source