Results 51 to 60 of about 35,640 (270)

Governance of biotechnology in Africa: the challenge of reconciling interdependencies and differences [PDF]

, 2012
The article argues that an informed understanding of the differences and interdependencies among different stakeholders within the biotechnology and biosafety arena is a key issue in the unpacking of challenges facing development and implementation of ...
Makinde, Diran, Mugwagwa, Julius
core  

Injectable Dual‐Network Hydrogel System for Osteochondral Repair Combining Immunomodulation, Mechanical Adaptability, and Enhanced Tissue Integration

Advanced Functional Materials, EarlyView.
A UV‐triggered injectable dual‐network hydrogel is reported as the first application of bletilla striata polysaccharide (BSP) in osteochondral repair. By integrating methacrylamide‐modified BSP and nitrobenzaldehyde‐functionalized hyaluronic acid, the system achieves immunomodulation, mechanical reinforcement, and dynamic tissue adhesion, thereby ...
Jiaming Cui, Feifei Zhou, Yuan Luo, Tao Ouyang, Huiwu Zhang, Songmiao Cheng, Qiang Li, Xu Jiang, Yingying Yu, Yicheng Wang, Hong Ming   +10 more
wiley   +1 more source

Gold Nanoclusters as Dual Agents for Engineering Tumor Vascular Leakiness and Performing Photothermal Therapy

Advanced Functional Materials, EarlyView.
Many cancer nanotherapeutics, while potent, suffer from the inability to escape from the tumor vasculature, especially in the absence of endothelial permeability. In this work, ultrasmall gold nanoclusters could engineer nanomaterials induced endothelial leakiness (NanoEL) and harness strong NIR induced photothermal characteristics to suppress tumor ...
Nengyi Ni, Kuoran Xing, Bihan Zhang, Baoteng Wang, Yinglu Chen, Jianping Xie, Xiao Sun, Jinping Wang, David Tai Leong   +8 more
wiley   +1 more source

Membrane Vesicles from Lacticaseibacillus Casei BL23 Exhibit Antimicrobial Activity Against Escherichia coli and Immunostimulatory Effects on Human Peripheral Blood Mononuclear Cells

Advanced Healthcare Materials, EarlyView.
Membrane vesicles derived from the probiotic Lacticaseibacillus casei BL23 demonstrate antimicrobial properties against Escherichia coli and a potential biological effect in improving the overall survival of C. elegans infected with Pseudomonas aeruginosa. These vesicles stimulated immune responses in primary cells without causing toxicity. Our results
Cecilia L. D'Antoni, Leila Pourtalebi Jahromi, Lorenzo Sana, Ana Paula Domínguez Rubio, Maja Dorfner, Jennifer Munkert, Heike Danzer, Philipp Arnold, Mikhail Lebedev, Esther Zanin, Oscar E. Pérez, Gregor Fuhrmann   +11 more
wiley   +1 more source

A transcription factor-mediated regulatory network controls fungal pathogen colonization of insect body cavities

mBio
Successful host tissue colonization is crucial for fungal pathogens to cause mycosis and complete the infection cycle, in which fungal cells undergo a series of morphological transition-included cellular events to combat with hosts.
Juan Deng, Shuaishuai Huang, Yanze Kan, Yue Song, Xin Zhao, Ning Li, Xuewen Yao, Zhibing Luo, Yongjun Zhang   +8 more
doaj   +1 more source

Smoke and Spike: Benzo[a]pyrene Enhances SARS‐CoV‐2 Infection by Boosting NR4A2‐Induced ACE2 and TMPRSS2 Expression

Advanced Science, 2023
Cigarette smoke aggravates severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection. However, the underlying mechanisms remain unclear.
Wenbin Liu, Yue Zhao, Junyan Fan, Jiaying Shen, Hailin Tang, Wanda Tang, Di Wu, Weijin Huang, Yibo Ding, Peng Qiao, Jiansheng Lin, Zishuai Li, Qianqian Li, Qianqian Cui, Yan Liu, Yifan Chen, Rui Pu, Xue Han, Jianhua Yin, Xiaojie Tan, Guangwen Cao   +20 more
doaj   +1 more source

[Education on biosafety and bioethics: necessary articulation in biotechnology].

Ciencia & saude coletiva, 2010
Science education has been discussed in some segments of the society and, international organizations have encouraged nations to invest in this strategic area. In this context, education in bioethics and biosafety explores a rich content on prevention, standards and ethical principles which serve to guide the paths track by biotechnology.
Marcos De, Bonis, Marco Antonio Ferreira da, Costa   +1 more
openaire   +1 more source

Socio-economic impact of GMOs on African consumers [PDF]

, 2009
The debate surrounding genetically modified organisms (GMOs) remains an important one for consumers and consumer organisations the world over, and is characterized by strong views for, and against the technology.
Mugwagwa, Julius T., Rutivi, Cathy
core   +1 more source

Few‐Layered Conductive Graphene Foams for Electrical Transdifferentiation of Mesenchymal Stem Cells Into Schwann Cell‐Like Phenotypes

Advanced Healthcare Materials, EarlyView.
Few‐layered three dimansional conductive graphene foams are promising cytocompatible platforms to transdifferentiate mesenchymal stem cells into Schwann cell‐like phenotypes using electrical and microstructural cues. Applied electrical stimulation conditions resulted in activation of MAPK, neurotrphin and RAS signaling pathways that led to upregulation
Ekin G. Simsar, Peifu Cheng, Tugce Dogruel, Maxsam Donta, Juhyung Jung, Naomi A. Asante, Donald S. Sakaguchi, Surya K. Mallapragada, Piran R. Kidambi, Metin Uz   +9 more
wiley   +1 more source

Construction and validation of an educational game on biosafety in the central sterile supply department

Revista Brasileira de Enfermagem
ABSTRACT Objectives: to construct and validate an educational game on biosafety in the Central Sterile Supply Department of a hospital in Curitiba, PR. Methods: the study was conducted using a quantitative approach, employing applied and technological research with an exploratory design. The process was divided into six stages, from the definition of
Tatiana Nemoto Piccoli Moraes, Fernanda Moura D’Almeida Miranda, Rafaela Danta de Sousa, Luciana Schleder Gonçalves, Maria de Fatima Mantovani, Jenira Priscila dos Anjos   +5 more
openaire   +3 more sources