Results 101 to 110 of about 120,566 (116)

DigFrag as a digital fragmentation method used for artificial intelligence-based drug design

Communications Chemistry
Fragment-Based Drug Design (FBDD) plays a pivotal role in the field of drug discovery and development. The construction of high-quality fragment libraries is a critical step in FBDD.
Ruoqi Yang, Hao Zhou, Fan Wang, Guangfu Yang   +3 more
doaj   +1 more source

Ischemic axonal injury up-regulates MARK4 in cortical neurons and primes tau phosphorylation and aggregation. [PDF]

, 2019
Ischemic injury to white matter tracts is increasingly recognized to play a key role in age-related cognitive decline, vascular dementia, and Alzheimer's disease.
Bitan, Gal, Charreton, Malena, Dutta, Suman, Hayden, Eric Y, Hinman, Jason D, Jiang, Lin, Joy, Mary Teena, Komuro, Yutaro, Li, Zizheng, MacKenzie-Graham, Allan, Nunez, Stefanie, Oberoi, Mandavi, Putman, Jennifer, Shin, Woo Shik   +13 more
core  

Development of conductometric biosensors based on alkaline phosphatases for the water quality control [PDF]

arXiv, 2008
Researches are focused on the elaboration of enzymatic microconductometric device for heavy metal ions detection in water solutions. The manuscript includes a general introduction, the first chapter contains bibliographic review, the second chapter described the fundamentals of conductometric transducers, the third chapter examining the possibility to ...
arxiv  

Laser-Induced Graphene-Based Gas Sensor with PEDOT:PSS/Gold–Platinum Nanocomposites for Highly Sensitive Detection of Methane

Chemosensors
Methane is a common intestinal gas that has been linked to a variety of gastrointestinal disorders. In this study, we prepared a LIG-based electrochemical sensor modified with PEDOT:PSS/Au-Pt nanocomposites for high-sensitivity methane detection.
Jiaying Sun, Zhuoru Huang, Xiaojing Zhang, Hangming Xiong, Weijie Yu, Shimeng Mou, Wenwu Zhu, Hao Wan   +7 more
doaj   +1 more source

PCR Master Mix Volume Calculators in JavaScript™

BioTechniques, 1998
Robert M. Horton, Remington J.S. Stone
doaj   +1 more source

A Fully-Printed Wearable Bandage-Based Electrochemical Sensor with pH Correction for Wound Infection Monitoring

Nano-Micro Letters
Highlights The first example of a flexible array capable of detecting pyocyanin, a bacterial virulence factor, while correcting dynamic pH fluctuations.
Kanyawee Kaewpradub, Kornautchaya Veenuttranon, Husanai Jantapaso, Pimonsri Mittraparp-arthorn, Itthipon Jeerapan   +4 more
doaj   +1 more source

A Virtual Molecular Biology Teaching Laboratory

BioTechniques, 1999
Robert M. Horton, Robert C. Tait
doaj   +1 more source

Flexible Polymer-Based Electrodes for Detecting Depression-Related Theta Oscillations in the Medial Prefrontal Cortex

Chemosensors
This study investigates neural activity changes in the medial prefrontal cortex (mPFC) of a lipopolysaccharide (LPS)-induced acute depression mouse model using flexible polymer multichannel electrodes, local field potential (LFP) analysis, and a ...
Rui Sun, Shunuo Shang, Qunchen Yuan, Ping Wang, Liujing Zhuang   +4 more
doaj   +1 more source

A visible light-activated azo-fluorescent switch for imaging-guided and light-controlled release of antimycotics

Nature Communications
Azo switches are widely employed as essential components in light-responsive systems. Here, we develop an azo-fluorescent switch that is visible light-responsive and its light-responsive processes can be monitored using fluorescence imaging.
Yurou Huang, Xiaoyan Zeng, Xiaoxie Ma, Zibo Lin, Jiayue Sun, Wang Xiao, Sheng Hua Liu, Jun Yin, Guang-Fu Yang   +8 more
doaj   +1 more source

Photonic biosensing via Su-Schrieffer-Heeger boundary modes [PDF]

arXiv
We propose a conceptual device for multiplexed biosensor in a photonic crystal chip based on the Su-Schrieffer-Heeger mechanism. Remarkably, the proposed biosensor can identify three distinct disease markers through a single-shot photon transmission measurement, due to the couplings among the three Su-Schrieffer-Heeger boundary modes in the photonic ...
arxiv