Results 21 to 30 of about 125,753 (295)

Optical biosensors [PDF]

open access: yesEssays in Biochemistry, 2016
Optical biosensors represent the most common type of biosensor. Here we provide a brief classification, a description of underlying principles of operation and their bioanalytical applications. The main focus is placed on the most widely used optical biosensors which are surface plasmon resonance (SPR)-based biosensors including SPR imaging and ...
Damborský, Pavel   +2 more
openaire   +2 more sources

Biosensores

open access: yesRevista de Ciencias, 2011
La realización de mediciones sensibles, selectivas y confiables en células y tejidos vivos es una labor interesante, y un proyecto muy importante para químicos, médicos, fisiólogos y profesionales clínicos, pues abre la posibilidad de estudiar procesos metabólicos y mecanismos a un nivel bioclínico y fisiológico.
Cedeño, David, Jaramillo, Alonso
openaire   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

In-situ profiling of glycosylation on single cells with surface plasmon resonance imaging

open access: yesNature Communications
Cellular glycosylation is crucial for cell recognition, signal transduction, and the development of various diseases, especially in tumor initiation, progression, and metastasis.
Xiaoyin Liu   +8 more
doaj   +1 more source

Self-supervised representation learning using feature pyramid siamese networks for colorectal polyp detection

open access: yesScientific Reports, 2023
Colorectal cancer is a leading cause of cancer-related deaths globally. In recent years, the use of convolutional neural networks in computer-aided diagnosis (CAD) has facilitated simpler detection of early lesions like polyps during real-time ...
Tianyuan Gan   +5 more
doaj   +1 more source

Acoustic biosensors [PDF]

open access: yesEssays in Biochemistry, 2016
Resonant and acoustic wave devices have been researched for several decades for application in the gravimetric sensing of a variety of biological and chemical analytes. These devices operate by coupling the measurand (e.g. analyte adsorption) as a modulation in the physical properties of the acoustic wave (e.g.
Fogel, Ronen   +2 more
openaire   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

An In Vitro HL-1 Cardiomyocyte-Based Olfactory Biosensor for Olfr558-Inhibited Efficiency Detection

open access: yesChemosensors, 2022
Some short-chain fatty acids with a pungent or unpleasant odor are important components of human body odor. These malodors severely threaten human health.
Qunchen Yuan   +9 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Evaluating the efficacy and cardiotoxicity of EGFR-TKI AC0010 with a novel multifunctional biosensor

open access: yesMicrosystems & Nanoengineering, 2023
Non-small cell lung cancer (NSCLC) is a leading cause of cancer mortality worldwide. Although epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) have dramatically improved the life expectancy of patients with NSCLC, concerns about ...
Deming Jiang   +11 more
doaj   +1 more source

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