Results 31 to 40 of about 1,499,955 (388)

Uncovering the cytochrome P450-catalyzed methylenedioxy bridge formation in streptovaricins biosynthesis

open access: yesNature Communications, 2020
Streptovaricin C is an antibiotic containing a methylenedioxy bridge (MDB) moiety essential for its activity. Here, the authors show that a P450 monooxygenase StvP2 catalyses MDB formation, report its crystal structure in complex with the substrate, and ...
Guo Sun   +9 more
doaj   +1 more source

Biosynthesis of α-Tocopherol and Plastoquinone-9 in spinach chloroplasts [PDF]

open access: yes, 1980
Prenylation and methylation reaction in al biosynthesis is localized in the envelope membranes of the chloroplasts, while PQ-9 biosynthesis takes place in the envelope membranes and also in the thylakoid membranes.
Mazliak, P.   +2 more
core   +1 more source

Regulation of Ergosterol Biosynthesis in Saccharomyces cerevisiae

open access: yesGenes, 2020
Ergosterol is an essential component of fungal cell membranes that determines the fluidity, permeability and activity of membrane-associated proteins.
Tania Jordá, S. Puig
semanticscholar   +1 more source

Aspergillus westerdijkiae polyketide synthase gene “aoks1” is involved in the biosynthesis of ochratoxin A [PDF]

open access: yes, 2009
OchratoxinA (OTA) is a potential nephrotoxic, teratogenic, immunogenic, hepatotoxic and carcinogenic mycotoxin, produced by Aspergillus westerdijkiae NRRL 3174.
Atoui, Ali   +4 more
core   +1 more source

Revolution of vitamin E production by starting from microbial fermented farnesene to isophytol

open access: yesThe Innovation, 2022
Vitamin E is one of the most widely used vitamins. In the classical commercial synthesis of vitamin E (α-tocopherol), the chemical synthesis of isophytol is the key technical barrier.
Ziling Ye   +12 more
doaj   +1 more source

Interplay between carotenoids, abscisic acid and jasmonate guides the compatible rice-Meloidogyne graminicola interaction [PDF]

open access: yes, 2017
In this study, we have characterized the role of carotenoids and chlorophyll in the compatible interaction between the sedentary root knot nematode (RKN) Meloidogyne graminicola and the monocot model plant rice (Oryza sativa). Previous transcriptome data
Demeestere, Kristof   +5 more
core   +5 more sources

The Taxus genome provides insights into paclitaxel biosynthesis

open access: yesNature Plants, 2021
The ancient gymnosperm genus Taxus is the exclusive source of the anticancer drug paclitaxel, yet no reference genome sequences are available for comprehensively elucidating the paclitaxel biosynthesis pathway. We have completed a chromosome-level genome
Xingyao Xiong   +18 more
semanticscholar   +1 more source

OsTTG1, a WD40 repeat gene, regulates anthocyanin biosynthesis in rice.

open access: yesThe Plant Journal, 2021
Anthocyanins play an important role in the growth of plants and are beneficial to human health. In plants, the MYB-bHLH-WD40 (MBW) complex activates the genes for anthocyanin biosynthesis.
Xinghai Yang   +16 more
semanticscholar   +1 more source

A Cysteine-Reloading Process Initiating the Biosynthesis of the Bicyclic Scaffold of Dithiolopyrrolones

open access: yesAntibiotics, 2023
Dithiolopyrrolone antibiotics are well known for their outstanding biological activities, and their biosynthesis has been studied vigorously. However, the biosynthesis mechanism of the characteristic bicyclic scaffold is still unknown after years of ...
Yan Chen   +4 more
doaj   +1 more source

A truncated lipoglycan from mycobacteria with altered immunological properties [PDF]

open access: yes, 2010
Maintenance of cell-wall integrity in Mycobacterium tuberculosis is essential and is the target of several antitubercular drugs. For example, ethambutol targets arabinogalactan and lipoarabinomannan (LAM) biosynthesis through the inhibition of several ...
Alderwick, Luke J.   +9 more
core   +2 more sources

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