Results 31 to 40 of about 1,261,328 (293)

Natural Products from Mangrove Actinomycetes

open access: yesMarine Drugs, 2014
Mangroves are woody plants located in tropical and subtropical intertidal coastal regions. The mangrove ecosystem is becoming a hot spot for natural product discovery and bioactivity survey.
Dong-Bo Xu   +4 more
doaj   +1 more source

A 5-Enolpyruvylshikimate 3-Phosphate Synthase Functions as a Transcriptional Repressor in Populus. [PDF]

open access: yes, 2018
Long-lived perennial plants, with distinctive habits of inter-annual growth, defense, and physiology, are of great economic and ecological importance.
Barros-Rios, Jaime   +28 more
core   +1 more source

FabR regulates Salmonella biofilm formation via its direct target FabB [PDF]

open access: yes, 2016
Background: Biofilm formation is an important survival strategy of Salmonella in all environments. By mutant screening, we showed a knock-out mutant of fabR, encoding a repressor of unsaturated fatty acid biosynthesis (UFA), to have impaired biofilm ...
De Coster, David   +8 more
core   +4 more sources

Arzanol, a prenylated heterodimeric phloroglucinyl pyrone, inhibits eicosanoid biosynthesis and exhibits anti-inflammatory efficacy in vivo. [PDF]

open access: yes, 2011
Based on its capacity to inhibit in vitro HIV-1 replication in T cells and the release of pro-inflammatory cytokines in monocytes, the prenylated heterodimeric phloroglucinyl α-pyrone arzanol was identified as the major anti-inflammatory and anti-viral ...
Appendino G   +8 more
core   +1 more source

A new type of DNA phosphorothioation-based antiviral system in archaea

open access: yesNature Communications, 2019
The prokaryote defence system Dnd relies on phosphorothioation (PT) of DNA backbone to distinguish between self and non-self DNA. Here, Xiong et al. describe a previously uncharacterized PT-based antiviral system that is independent of the canonical Dnd ...
Lei Xiong   +12 more
doaj   +1 more source

Puromycin A, B and C, cryptic nucleosides identified from Streptomyces alboniger NRRL B-1832 by PPtase-based activation

open access: yesSynthetic and Systems Biotechnology, 2018
Natural product discovery is pivot for drug development, however, this endeavor is often challenged by the wide inactivation or silence of natural products biosynthetic pathways.
Xiaoli Yan   +8 more
doaj   +1 more source

Tocopherol and plastoquinone synthesis in spinach chloroplasts subfractions [PDF]

open access: yes, 1980
Subfractions isolated from intact purified spinach chloroplasts are able to prenylate the aromatic moiety of -tocopherol and plastoquinone-9 precursors. The biosynthesis of -tocopherol and plastoquinone-9 is a compartmentalized process.
Bickel   +21 more
core   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Coenzyme Q10 deficiencies: pathways in yeast and humans. [PDF]

open access: yes, 2018
Coenzyme Q (ubiquinone or CoQ) is an essential lipid that plays a role in mitochondrial respiratory electron transport and serves as an important antioxidant.
Awad, Agape M   +5 more
core  

Collagens - structure, function and biosynthesis. [PDF]

open access: yes, 2003
The extracellular matrix represents a complex alloy of variable members of diverse protein families defining structural integrity and various physiological functions.
Aigner, T, Gelse, K, Poschl, E
core   +1 more source

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