Biosynthesis of Sespendole [PDF]
The Journal of Antibiotics, 2006 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Ryuji, Uchida +2 more
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The biosynthesis of glucosamine [PDF]
Biochimica et Biophysica Acta, 1953 Abstract A partially purified enzyme has been prepared from Neurospora crassa which catalyzes the formation of glucosamine phosphate from hexose-6-phosphate and glutamine. The glucosamine phosphate was identified by colour reactions, by dephosphorylation and paper chromatography and by its behaviour towards an acetylating system.
Leloir, Luis Federico +1 more
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Aspergillus westerdijkiae polyketide synthase gene “aoks1” is involved in the biosynthesis of ochratoxin A [PDF]
, 2009 OchratoxinA (OTA) is a potential nephrotoxic, teratogenic, immunogenic, hepatotoxic and carcinogenic mycotoxin, produced by Aspergillus westerdijkiae NRRL 3174.
Atoui, Ali +4 more
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Nature Communications, 2020 Streptovaricin C is an antibiotic containing a methylenedioxy bridge (MDB) moiety essential for its activity. Here, the authors show that a P450 monooxygenase StvP2 catalyses MDB formation, report its crystal structure in complex with the substrate, and ...
Guo Sun +9 more
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Regulation of cyclic lipopeptide biosynthesis in Pseudomonas fluorescens by the ClpP protease [PDF]
, 2009 Cyclic lipopeptides produced by Pseudomonas species exhibit potent surfactant and broad-spectrum antibiotic properties. Their biosynthesis is governed by large multimodular nonribosomal peptide synthetases, but little is known about the genetic ...
Bruijn, I., de, Raaijmakers, J.M.
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CdsA is involved in biosynthesis of glycolipid MPIase essential for membrane protein integration in vivo [PDF]
, 2021 MPIase is a glycolipid that is involved in membrane protein integration. Despite evaluation of its functions in vitro, the lack of information on MPIase biosynthesis hampered verification of its involvement in vivo. In this study, we found that depletion
IIMURA, Naoki +12 more
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Diversity and functional analysis of LuxR-type transcriptional regulators of cyclic lipopeptide biosynthesis in Pseudomonas fluorescens [PDF]
, 2009 Cyclic lipopeptides (CLPs) are produced by many Pseudomonas species and have several biological functions, including a role in surface motility, biofilm formation, virulence, and antimicrobial activity.
Bruijn, I., de, Raaijmakers, J.M.
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Revolution of vitamin E production by starting from microbial fermented farnesene to isophytol
The Innovation, 2022 Vitamin E is one of the most widely used vitamins. In the classical commercial synthesis of vitamin E (α-tocopherol), the chemical synthesis of isophytol is the key technical barrier.
Ziling Ye +12 more
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The biosynthesis of dicoumarol [PDF]
Biochemical Journal, 1967 Micro-organisms have been isolated that can utilize o-coumaric acid as a sole carbon source with the subsequent production of 4-hydroxycoumarin and dicoumarol. One of these organisms, Penicillium jenseni, has been used to examine the biosynthesis of dicoumarol.
D M, Bellis, M S, Spring, J R, Stoker
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Inhibitors incorporating zinc-binding groups target the GlcNAc-PI de-N-acetylase in Trypanosoma brucei, the causative agent of African sleeping sickness [PDF]
, 2012 Disruption of glycosylphosphatidylinositol biosynthesis is genetically and chemically validated as a drug target against the protozoan parasite Trypanosoma brucei, the causative agent of African sleeping sickness.
Crossman, Arthur T. +4 more
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