Results 21 to 30 of about 900,154 (308)

A Cysteine-Reloading Process Initiating the Biosynthesis of the Bicyclic Scaffold of Dithiolopyrrolones

open access: yesAntibiotics, 2023
Dithiolopyrrolone antibiotics are well known for their outstanding biological activities, and their biosynthesis has been studied vigorously. However, the biosynthesis mechanism of the characteristic bicyclic scaffold is still unknown after years of ...
Yan Chen   +4 more
doaj   +1 more source

Oxidation of unsaturated fatty acids by leaf tissue

open access: yesJournal of Lipid Research, 1964
Plant leaf systems have been incubated under various conditions with uniformly labeled oleic acid, and the breakdown products identified by gas–liquid chromatography.
C. Hitchcock, A.T. James
doaj   +1 more source

Expression and gene regulatory network of SNHG1 in hepatocellular carcinoma

open access: yesBMC Medical Genomics, 2021
Background Small nucleolar RNA host gene 1 (SNHG1), a long noncoding RNA (lncRNA), is a transcript that negatively regulates tumour suppressor genes, such as p53. Abnormal SNHG1 expression is associated with cell proliferation and cancer.
Chaoran Zheng, Shicheng Yu
doaj   +1 more source

THE BIOSYNTHESIS OF SUCROSE

open access: yesJournal of Biological Chemistry, 1955
The enzyme, which was named sucrose phosphorylase, has not been found in plant tissues (4), and thus the mechanism of sucrose synthesis remains obscure. Evidence obtained from tracer experiments led Buchanan et al. (5, 6) to assume that in plants sucrose phosphate is formed from UDPG’ and fructose-l-phosphate.
Cardini, Carlos E.   +2 more
openaire   +3 more sources

Biosynthesis of Largimycins in Streptomyces argillaceus Involves Transient β‑Alkylation and Cryptic Halogenation Steps Unprecedented in the Leinamycin Family [PDF]

open access: yes, 2022
Largimycins A1 and A2 are key members of a recently identified family of hybrid nonribosomal peptide polyketides belonging to the scarcely represented group of antitumor leinamycins.
Becerril García, Adriana   +5 more
core  

Biosynthesis of Prostaglandins [PDF]

open access: yesAnnual Review of Nutrition, 1991
Highly purified cyclooxygenase from sheep vesicular glands is stimulated by the presence of protoporphyrin IX compounds. This stimulation may be due to the conversion of an apoenzyme to the holoenzyme, and full activity is achieved when half of the enzyme subunits (70,000 daltons) bind heme.
openaire   +2 more sources

The effects of estrogen on targeted cancer therapy drugs

open access: yesPharmacological Research, 2022
Improving the efficacy of anticancer drugs is especially challenging. Estrogen is a sex hormone that not only promotes the development of female secondary sexual characteristics, but also supports many important physiological functions.
Ying Zhao   +4 more
doaj   +1 more source

Plant sterol metabolism with emphasis on glycoalkaloid biosynthesis in potato [PDF]

open access: yes, 2007
Glycoalkaloids are secondary metabolites present within species of the family Solanaceae. They are toxic to humans and animals, and it is important to keep the levels in potato (Solanum tuberosum L.) tubers below the safe limit for consumption ...
Arnqvist, Lisa
core   +1 more source

Efficient biosynthesis of nucleoside cytokinin angustmycin A containing an unusual sugar system

open access: yesNature Communications, 2021
Angustmycin A is a nucleoside antibiotic having anti-mycobacterial and cytokinin activities. Here, the authors report the whole pathway leading to angustmycin A biosynthesis in Streptomyces and achieve the heterologous production of angustmycin A in E ...
Le Yu   +8 more
doaj   +1 more source

Environmental degradation of plastics containing pro-oxidant additives and their toxicological impact in desert ecosystems

open access: yesCase Studies in Chemical and Environmental Engineering
The accumulation of single-use plastic materials poses significant environmental and waste management challenges. Pro-oxidant additive-containing (PAC) plastics have been introduced in many regions to mitigate these impacts.
Diya Alsafadi   +5 more
doaj   +1 more source

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