Results 21 to 30 of about 900,154 (308)
Dithiolopyrrolone antibiotics are well known for their outstanding biological activities, and their biosynthesis has been studied vigorously. However, the biosynthesis mechanism of the characteristic bicyclic scaffold is still unknown after years of ...
Yan Chen +4 more
doaj +1 more source
Oxidation of unsaturated fatty acids by leaf tissue
Plant leaf systems have been incubated under various conditions with uniformly labeled oleic acid, and the breakdown products identified by gas–liquid chromatography.
C. Hitchcock, A.T. James
doaj +1 more source
Expression and gene regulatory network of SNHG1 in hepatocellular carcinoma
Background Small nucleolar RNA host gene 1 (SNHG1), a long noncoding RNA (lncRNA), is a transcript that negatively regulates tumour suppressor genes, such as p53. Abnormal SNHG1 expression is associated with cell proliferation and cancer.
Chaoran Zheng, Shicheng Yu
doaj +1 more source
The enzyme, which was named sucrose phosphorylase, has not been found in plant tissues (4), and thus the mechanism of sucrose synthesis remains obscure. Evidence obtained from tracer experiments led Buchanan et al. (5, 6) to assume that in plants sucrose phosphate is formed from UDPG’ and fructose-l-phosphate.
Cardini, Carlos E. +2 more
openaire +3 more sources
Biosynthesis of Largimycins in Streptomyces argillaceus Involves Transient β‑Alkylation and Cryptic Halogenation Steps Unprecedented in the Leinamycin Family [PDF]
Largimycins A1 and A2 are key members of a recently identified family of hybrid nonribosomal peptide polyketides belonging to the scarcely represented group of antitumor leinamycins.
Becerril García, Adriana +5 more
core
Biosynthesis of Prostaglandins [PDF]
Highly purified cyclooxygenase from sheep vesicular glands is stimulated by the presence of protoporphyrin IX compounds. This stimulation may be due to the conversion of an apoenzyme to the holoenzyme, and full activity is achieved when half of the enzyme subunits (70,000 daltons) bind heme.
openaire +2 more sources
The effects of estrogen on targeted cancer therapy drugs
Improving the efficacy of anticancer drugs is especially challenging. Estrogen is a sex hormone that not only promotes the development of female secondary sexual characteristics, but also supports many important physiological functions.
Ying Zhao +4 more
doaj +1 more source
Plant sterol metabolism with emphasis on glycoalkaloid biosynthesis in potato [PDF]
Glycoalkaloids are secondary metabolites present within species of the family Solanaceae. They are toxic to humans and animals, and it is important to keep the levels in potato (Solanum tuberosum L.) tubers below the safe limit for consumption ...
Arnqvist, Lisa
core +1 more source
Efficient biosynthesis of nucleoside cytokinin angustmycin A containing an unusual sugar system
Angustmycin A is a nucleoside antibiotic having anti-mycobacterial and cytokinin activities. Here, the authors report the whole pathway leading to angustmycin A biosynthesis in Streptomyces and achieve the heterologous production of angustmycin A in E ...
Le Yu +8 more
doaj +1 more source
The accumulation of single-use plastic materials poses significant environmental and waste management challenges. Pro-oxidant additive-containing (PAC) plastics have been introduced in many regions to mitigate these impacts.
Diya Alsafadi +5 more
doaj +1 more source

