Results 21 to 30 of about 794,439 (319)

Biosynthesis of C-nucleoside antibiotics in actinobacteria: recent advances and future developments

open access: yesMicrobial Cell Factories, 2022
Epidemic diseases and antibiotic resistance are urgent threats to global health, and human is confronted with an unprecedented dilemma to conquer them by expediting development of new natural product related drugs.
Meng Zhang   +7 more
doaj   +1 more source

Effects of cadmium stress on seed germination and physiological-biochemical characteristics in okra: a comparative study of red and green varieties [PDF]

open access: yesPeerJ
Previous study has demonstrated that okra (Abelmoschus esculentus (L.) Moench) is capable of accumulating cadmium (Cd) in both plants and fruits. However, there is still little known about the physiological responses of different okra cultivars to Cd ...
Wanwan Wang   +6 more
doaj   +2 more sources

Aspergillus westerdijkiae polyketide synthase gene “aoks1” is involved in the biosynthesis of ochratoxin A [PDF]

open access: yes, 2009
OchratoxinA (OTA) is a potential nephrotoxic, teratogenic, immunogenic, hepatotoxic and carcinogenic mycotoxin, produced by Aspergillus westerdijkiae NRRL 3174.
Atoui, Ali   +4 more
core   +1 more source

Engineering Corynebacterium glutamicum for de novo production of 2-phenylethanol from lignocellulosic biomass hydrolysate

open access: yesBiotechnology for Biofuels and Bioproducts, 2023
Background 2-Phenylethanol is a specific aromatic alcohol with a rose-like smell, which has been widely used in the cosmetic and food industries. At present, 2-phenylethanol is mainly produced by chemical synthesis.
Nianqing Zhu   +6 more
doaj   +1 more source

Uncovering the cytochrome P450-catalyzed methylenedioxy bridge formation in streptovaricins biosynthesis

open access: yesNature Communications, 2020
Streptovaricin C is an antibiotic containing a methylenedioxy bridge (MDB) moiety essential for its activity. Here, the authors show that a P450 monooxygenase StvP2 catalyses MDB formation, report its crystal structure in complex with the substrate, and ...
Guo Sun   +9 more
doaj   +1 more source

Biosynthesis of Prostaglandins [PDF]

open access: yesAnnual Review of Nutrition, 1991
Highly purified cyclooxygenase from sheep vesicular glands is stimulated by the presence of protoporphyrin IX compounds. This stimulation may be due to the conversion of an apoenzyme to the holoenzyme, and full activity is achieved when half of the enzyme subunits (70,000 daltons) bind heme.
openaire   +2 more sources

Revolution of vitamin E production by starting from microbial fermented farnesene to isophytol

open access: yesThe Innovation, 2022
Vitamin E is one of the most widely used vitamins. In the classical commercial synthesis of vitamin E (α-tocopherol), the chemical synthesis of isophytol is the key technical barrier.
Ziling Ye   +12 more
doaj   +1 more source

Oxidation of unsaturated fatty acids by leaf tissue

open access: yesJournal of Lipid Research, 1964
Plant leaf systems have been incubated under various conditions with uniformly labeled oleic acid, and the breakdown products identified by gas–liquid chromatography.
C. Hitchcock, A.T. James
doaj   +1 more source

Expression and gene regulatory network of SNHG1 in hepatocellular carcinoma

open access: yesBMC Medical Genomics, 2021
Background Small nucleolar RNA host gene 1 (SNHG1), a long noncoding RNA (lncRNA), is a transcript that negatively regulates tumour suppressor genes, such as p53. Abnormal SNHG1 expression is associated with cell proliferation and cancer.
Chaoran Zheng, Shicheng Yu
doaj   +1 more source

The biosynthesis of the cannabinoids [PDF]

open access: yesJournal of Cannabis Research, 2021
Abstract Cannabis has been integral to Eurasian civilization for millennia, but a century of prohibition has limited investigation. With spreading legalization, science is pivoting to study the pharmacopeia of the cannabinoids, and a thorough understanding of their biosynthesis is required to engineer strains with specific ...
M. Nazir Tahir   +3 more
openaire   +3 more sources

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