Results 41 to 50 of about 872,410 (312)

Diversity and Evolution of the Phenazine Biosynthesis Pathway [PDF]

open access: yes, 2010
Phenazines are versatile secondary metabolites of bacterial origin that function in biological control of plant pathogens and contribute to the ecological fitness and pathogenicity of the producing strains.
Blankenfeldt, Wulf   +38 more
core   +1 more source

Environmental degradation of plastics containing pro-oxidant additives and their toxicological impact in desert ecosystems

open access: yesCase Studies in Chemical and Environmental Engineering
The accumulation of single-use plastic materials poses significant environmental and waste management challenges. Pro-oxidant additive-containing (PAC) plastics have been introduced in many regions to mitigate these impacts.
Diya Alsafadi   +5 more
doaj   +1 more source

Biosynthesis of fucoxanthin and diadinoxanthin and function of initial pathway genes in Phaeodactylum tricornutum [PDF]

open access: yes, 2012
The biosynthesis pathway to diadinoxanthin and fucoxanthin was elucidated in Phaeodactylum tricornutum by a combined approach involving metabolite analysis identification of gene function.
Sandmann, Gerhard   +5 more
core   +1 more source

The role of the phosphopantetheinyltransferase enzyme, PswP, in the biosynthesis of antimicrobial secondary metabolites by Serratia marcescens Db10 [PDF]

open access: yes, 2014
Phosphopantetheinyl transferase (PPTase) enzymes fulfil essential roles in primary and secondary metabolism in prokaryotes, archaea and eukaryotes. PPTase enzymes catalyse the essential modification of the carrier protein domain of fatty acid synthases ...
Gerc, Amy J.   +2 more
core   +1 more source

Puromycin A, B and C, cryptic nucleosides identified from Streptomyces alboniger NRRL B-1832 by PPtase-based activation

open access: yesSynthetic and Systems Biotechnology, 2018
Natural product discovery is pivot for drug development, however, this endeavor is often challenged by the wide inactivation or silence of natural products biosynthetic pathways.
Xiaoli Yan   +8 more
doaj   +1 more source

Plant sterol metabolism with emphasis on glycoalkaloid biosynthesis in potato [PDF]

open access: yes, 2007
Glycoalkaloids are secondary metabolites present within species of the family Solanaceae. They are toxic to humans and animals, and it is important to keep the levels in potato (Solanum tuberosum L.) tubers below the safe limit for consumption ...
Arnqvist, Lisa
core   +1 more source

A new type of DNA phosphorothioation-based antiviral system in archaea

open access: yesNature Communications, 2019
The prokaryote defence system Dnd relies on phosphorothioation (PT) of DNA backbone to distinguish between self and non-self DNA. Here, Xiong et al. describe a previously uncharacterized PT-based antiviral system that is independent of the canonical Dnd ...
Lei Xiong   +12 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Functional analysis of the Lactococcus lactis galU and galE genes and their impact on sugar nucleotide and exopolysaccharide biosynthesis [PDF]

open access: yes, 2001
We studied the UDP-glucose pyrophosphorylase (galU) and UDP-galactose epimerase (galE) genes of Lactococcus lactis MG1363 to investigate their involvement in biosynthesis of UDP-glucose and UDP-galactose, which are precursors of glucose- and galactose ...
Boels, I.C.   +4 more
core   +1 more source

Natural Products from Mangrove Actinomycetes

open access: yesMarine Drugs, 2014
Mangroves are woody plants located in tropical and subtropical intertidal coastal regions. The mangrove ecosystem is becoming a hot spot for natural product discovery and bioactivity survey.
Dong-Bo Xu   +4 more
doaj   +1 more source

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