Results 51 to 60 of about 1,261,328 (293)

Long-chain alkanol–alkyl carboxylic acid-based low-viscosity hydrophobic deep eutectic solvents for one-pot extraction of anthraquinones from Rhei Radix et Rhizoma

Journal of Pharmaceutical Analysis, 2022
Natural long-chain alkanol and alkyl carboxylic acid were used to prepare novel hydrophobic deep eutectic solvents (HDESs). These HDESs are liquid at room temperature and have low viscosity (
Anqi Huang, Wenwen Deng, Xiao Li, Qutong Zheng, Xuanxuan Wang, Yuxiu Xiao   +5 more
doaj   +1 more source

Maritime pine PpMYB8 directly co-regulates secondary cell wall architecture and the associated Phe-biosynthesis pathway [PDF]

, 2018
Plants rely on the biosynthesis of L-Phenylalanine as building block for the synthesis of proteins but also as precursor for a tremendous range of plant-derived compounds essential for its grown, development and defense.
Canlet, Francis, Canovas-Ramos, Francisco Miguel, De la Torre, Fernando, Debille, Sandrine, El-Azaz Ciudad, Jorge, Pascual, Mª Belén, Trontin, Jean-Francois, Ávila, Concepción   +7 more
core  

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Does abscisic acid affect strigolactone biosynthesis? [PDF]

, 2010
Strigolactones are considered a novel class of plant hormones that, in addition to their endogenous signalling function, are exuded into the rhizosphere acting as a signal to stimulate hyphal branching of arbuscular mycorrhizal (AM) fungi and germination
Adie, Akiyama, Alder, Andrew J. Thompson, Anna K. Undas, Aroca, Auldridge, Bainbridge, Bethke, Booker, Booker, Bouwmeester, Bouwmeester, Burbidge, Carbone, Carolien Ruyter-Spira, Christmann, Cook, Cornish, Cutler, Davies, De Smet, Dunlap, Ejeta, Francel Verstappen, Fraser, Gomez-Roldan, Harrison, Harro Bouwmeester, Hernandez, Herrera-Medina, Jeschke, Jiang, Juan A. López-Ráez, Kahn, Kitahata, Li, Livak, López-Ráez, López-Ráez, López-Ráez, López-Ráez, Martin J. Sergeant, Matusova, Misson, Nitsch, Parry, Parry, Paszkowski, Patrick Mulder, Rani, Rock, Sagi, Saika, Schwartz, Schwartz, Schwartz, Sergeant, Simkin, Sorefan, Spinsanti, Strack, Sun, Tan, Tatsiana Charnikhova, Taylor, Taylor, Thompson, Thompson, Timothy D. H. Bugg, Umehara, Vogel, Wasaki, Wouter Kohlen, Yoneyama, Yoneyama, Zeevaart   +76 more
core   +4 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Mutation of the inducible ARABIDOPSIS THALIANA CYTOCHROME P450 REDUCTASE2 alters lignin composition and improves saccharification [PDF]

, 2014
ARABIDOPSIS THALIANA CYTOCHROME P450 REDUCTASE1 (ATR1) and ATR2 provide electrons from NADPH to a large number of CYTOCHROME P450 (CYP450) enzymes in Arabidopsis (Arabidopsis thaliana).
Boerjan, Wout, Geerinck, Jan, Goeminne, Geert, Höfer, René, Kim, Hoon, Ralph, John, Sundin, Lisa, Vanholme, Ruben   +7 more
core   +2 more sources

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Cytochrome P450-catalyzed allylic oxidation of pentalenene to 1-deoxypentalenic acid in pentalenolactone biosynthesis

Engineering Microbiology
Pentalenolactone is a sesquiterpene antibiotic from Streptomyces. Its biosynthetic pathway has been elucidated, except for the oxidation of pentalen-13-al to 1-deoxypentalenic acid.
Jing Li, Chengde Zhang, Shiwen Wu, Jiao Xue, Ke Chen, Zixin Deng, Dongqing Zhu   +6 more
doaj   +1 more source