Results 61 to 70 of about 1,261,328 (293)

Non-target molecular network and putative genes of flavonoid biosynthesis in Erythrina velutina Willd., a Brazilian semiarid native woody plant [PDF]

, 2022
Daisy Sotero Chacon, Marlon Dias Mariano Santos, Bernardo Bonilauri, Johnatan Vilasboa, Cibele Tesser da Costa, Ivanice Bezerra da Silva, Taffarel Melo Torres, Thiago Ferreira de Araújo, Alan de Araújo Roque, Alan César Pilon, Denise Medeiros Selegatto, Rafael Teixeira Freire, Fernanda Priscila Santos Reginaldo, Eduardo Luiz Voigt, José Ângelo Silveira Zuanazzi, Kátia Castanho Scortecci, Alberto José Cavalheiro, Norberto Peporine Lopes, Leandro De Santis Ferreira, Leandro Vieira dos Santos, Wagner Fontes, Marcelo Valle de Sousa, Paulo C. Carvalho, Arthur Germano Fett‐Neto, Raquel Brandt Giordani   +24 more
openalex   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Advances in the optimization of central carbon metabolism in metabolic engineering

Microbial Cell Factories, 2023
Central carbon metabolism (CCM), including glycolysis, tricarboxylic acid cycle and the pentose phosphate pathway, is the most fundamental metabolic process in the activities of living organisms that maintains normal cellular growth.
Zhenke Wu, Xiqin Liang, Mingkai Li, Mengyu Ma, Qiusheng Zheng, Defang Li, Tianyue An, Guoli Wang   +7 more
doaj   +1 more source

ttl mutants are impaired in cellulose biosynthesis under osmotic stress [PDF]

, 2018
As sessile organisms, plants require mechanisms to sense and respond to the challenging environment, that encompass both biotic and abiotic factors that results in differential development.
Amorim-Silva, Vitor, Botella-Mesa, Miguel Angel, Castillo-Garriga, Araceli, García-Moreno, Álvaro, Jaillais, Yvon, Macho, Alberto, Valpuesta-Fernandez, Victoriano   +6 more
core  

Diverse biological effects of glycosyltransferase genes from Tartary buckwheat [PDF]

, 2019
Background: Tartary buckwheat (Fagopyrum tataricum) is an edible cereal crop whose sprouts have been marketed and commercialized for their higher levels of anti-oxidants, including rutin and anthocyanin. UDP-glucose flavonoid glycosyltransferases (UFGTs)
Chen, Hui, Deng, Renyu, Dong, Qixin, Huang, Yunji, Li, Chenglei, Li, Qi, Lv, Bingbing, Shi, Guanlan, Shi, Jiaqi, Stael, Simon, Wu, Qi, Yao, Panfeng, Zhao, Haixia   +12 more
core   +2 more sources

Novel Roles of SPATULA in the Control of Stomata and Trichome Number, and Anthocyanin Biosynthesis [PDF]

, 2023
Judith Jazmín Bernal-Gallardo, Víctor M. Zúñiga‐Mayo, Nayelli Marsch‐Martínez, Stefan de Folter   +3 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Development of Integrated Vectors with Strong Constitutive Promoters for High-Yield Antibiotic Production in Mangrove-Derived Streptomyces

Marine Drugs
It is important to improve the production of bioactive secondary products for drug development. The Escherichia coli—Streptomyces shuttle vector pSET152 and its derived vector pIB139 containing a strong constitutive promoter ermEp* are commonly used as ...
Mingxia Zhao, Zhiqiang Yang, Xinyue Li, Yaqi Liu, Yingying Zhang, Mengqian Zhang, Yangli Li, Xincheng Wang, Zixin Deng, Kui Hong, Dongqing Zhu   +10 more
doaj   +1 more source

Biosynthesis, characterization, and antifungal activity of plant-mediated silver nanoparticles using Cnidium monnieri fruit extract [PDF]

, 2023
Mingqi Ye, Wenwen Yang, Minxin Zhang, Huili Huang, Aiwen Huang, Bin Qiu   +5 more
openalex   +1 more source

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

Molecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf, Daniel Ehinger, Hans Brunnström, Mats Jönsson, Frida Rosengren, Marija Kotevska, Anna Karlsson, Mattias Aine, Christian Frezza, Maria Planck, Elsa Arbajian   +10 more
wiley   +1 more source