Independent channels for miRNA biosynthesis ensure efficient static and dynamic control in the regulation of the early stages of myogenesis [PDF]
Motivated by recent experimental work, we define and study a deterministic model of the complex miRNA-based regulatory circuit that putatively controls the early stage of myogenesis in human. We aim in particular at a quantitative understanding of (i) the roles played by the separate and independent miRNA biosynthesis channels (one involving a miRNA ...
arxiv +1 more source
Characteristics of aquatic biospheres on temperate planets around Sun-like stars and M-dwarfs [PDF]
Aquatic biospheres reliant on oxygenic photosynthesis are expected to play an important role on Earth-like planets endowed with large-scale oceans insofar as carbon fixation (i.e., biosynthesis of organic compounds) is concerned. We investigate the properties of aquatic biospheres comprising Earth-like biota for habitable rocky planets orbiting Sun ...
arxiv +1 more source
β-Cyclodextrin-Modified Laser-Induced Graphene Electrode for Detection of N6-Methyladenosine in RNA
Laser-induced graphene (LIG) possesses characteristics of easy handling, miniaturization, and unique electrical properties. We modified the surface of LIG by electropolymerizing β-cyclodextrin (β-CD), which was used to immobilize antibodies on the ...
Jingyi Guo+4 more
doaj +1 more source
Signature Arsenic Detoxification Pathways in
Since the original report that Halomonas sp. strain GFAJ-1 was capable of using arsenic instead of phosphorus to sustain growth, additional studies have been conducted, and GFAJ-1 is now considered a highly arsenic-resistant but phosphorus-dependent ...
Shuangju Wu+8 more
doaj +1 more source
Sphingolipid biosynthesis modulates plasmodesmal ultrastructure and phloem unloading [PDF]
During phloem unloading, multiple cell-to-cell transport events move organic substances to the root meristem. Although the primary unloading event from the sieve elements to the phloem pole pericycle has been characterized to some extent, little is known about post-sieve element unloading. Here, we report a novel gene, PHLOEM UNLOADING MODULATOR (PLM),
arxiv +1 more source
The combined effects of Feller diffusion and transcriptional/translational bursting in simple gene networks [PDF]
We study a stochastic model of biosynthesis of proteins in generic bacterial operons. The stochasticity arises from two different processes, namely from `bursting' production of either mRNA and/or protein (in the transcription/translation process) and from standard diffusive fluctuations.
arxiv +1 more source
Further characterization of Dothistromin genes in the fungal forest pathogen Dothistroma septosporum : a thesis presented in partial fulfilment of the requirements for the degree of Masters of Science in Molecular Genetics at Massey University, Palmerston North, New Zealand [PDF]
Dothistroma septosporum is a forest pathogen that causes a disease called Dothistroma needle blight. The symptoms are thought to be due to the accumulation of dothistromin toxin produced by D. septosporum.
Jin, Hong Ping
core
Parallel analysis of tri-molecular biosynthesis with cell identity and function in single cells. [PDF]
Cellular products derived from the activity of DNA, RNA, and protein synthesis collectively control cell identity and function. Yet there is little information on how these three biosynthesis activities are coordinated during transient and sparse ...
Baskar, Reema+3 more
core +2 more sources
Metabolic channeling of phe for lignin biosynthesis in maritime pine [PDF]
Phenylalanine (Phe) is the main precursor of phenylpropanoids biosynthesis in plants. This vast family of Phe-derived compounds can represent more than 30% of captured photosynthetic carbon, playing essential roles in plants such as cell wall components,
Canlet, Francis+8 more
core
Biosynthesis of lignans. Part I . Biosynthesis of Arctiin (3) and Phillyrin (5) [PDF]
Lignans constitute a class of naturally occuring phenolic compounds, widely distributed in higher plants. They are formally composed of two phenylpropanoid units, stercospecifically joined at the /f-carbon atoms of their side chains. Their biosynthesis
Klischies, Martina, Stöckigt, Joachim
core +1 more source