Results 201 to 210 of about 373,234 (333)

Identification and Characterization of the Sulfazecin Monobactam Biosynthetic Gene Cluster.

Cell Chemical Biology, 2017
Rongfeng Li, R. Oliver, C. Townsend
semanticscholar   +1 more source

In Vivo Characterization of the <i>dia</i> Biosynthetic Gene Cluster Reveals Diaporthinic Acid as Its Main Product. [PDF]

J Fungi (Basel)
Burger I, Leonhartsberger S, Peikert K, Fourtis L, Atanasova P, Kramer LTS, Fried R, Stanetty C, Rudroff F, Birner-Gruenberger R, Mach RL, Mach-Aigner AR, Schittmayer M, Zimmermann C.   +13 more
europepmc   +1 more source

NLSS3 Impairs SHM1 Autophagic Degradation to Regulate Leaf Morphology and Salt Tolerance in Rice

Advanced Science, EarlyView.
In rice, NLSS3 binds and shields SHM1 from autophagic degradation to maintain serine homeostasis. The A132P mutation in nlss3 disrupts this, triggering SHM1 loss, metabolic dysfunction, K+ imbalance, and impaired ROS scavenging, which collectively drive narrow leaves and salt sensitivity.
Xiong Liu, Yulu Yang, Zhiqi Hao, Jing Xu, Huibo Zhao, Qiang Zhang, Deyong Ren, Xia Li, Guojun Dong, Lan Shen, Li Zhu, Jiang Hu, Zhenyu Gao, Qing Li, Qian Qian, Guangheng Zhang   +15 more
wiley   +1 more source

One-step in vivo assembly of a 63 kb-long biosynthetic gene cluster via multiple recombination in Aspergillus oryzae. [PDF]

Appl Microbiol Biotechnol
Tamano K, Takayama H, Kozone I, Abe Y, Kanda A, Kudo K, Suenaga H, Shin-Ya K.   +7 more
europepmc   +1 more source

Ferritinophagy Rewires Carnitine‐Dependent Lipid Metabolism to Inhibit PRRSV and IAV Replication

Advanced Science, EarlyView.
NCOA4‐mediated ferritinophagy reprograms carnitine metabolism by disrupting Fe‐S cluster biogenesis, thereby establishing an iron‐lipid axis that suppresses various viruses, including PRRSV and IAV. However, viruses counteract this mechanism by degrading NCOA4.
Kaifeng Guan, Chenyang Yuan, Zekun Meng, Yanan Wang, Xueying Zhai, Chunjie Huang, Xiang Zhou, Gaiping Zhang   +7 more
wiley   +1 more source

Unraveling the metabolic potential and roles of reductases in the omicsynin biosynthetic gene cluster. [PDF]

Nat Prod Bioprospect
Li Y, Fu J, Sun H, Du Y, Si S, Li Y, Li X, Jiang J, Hong B.   +8 more
europepmc   +1 more source

NFYB Integrates Hormonal Signals into Tissue Allometry by Promoting Protein Biosynthesis

Advanced Science, EarlyView.
In the American cockroach, NFYB acts as a spatiotemporin that translates distinct hormonal cues into tissue‐specific allometry. Juvenile hormone activates NFYB in the early fat body, while 20‐hydroxyecdysone induces it in late wing pads. NFYB then promotes protein biosynthesis via core translational machinery, driving differential growth across the ...
Fangfang Liu, Shiming Zhu, Sishi Xia, Xiaoshuai Zhang, Qin Li, Zhanquan Zeng, Yuqing Liu, Wanyin Liang, Guanyu Zhou, Erxia Du, Suning Liu, Sheng Li   +11 more
wiley   +1 more source

The Maculalactone Biosynthetic Gene Cluster, a Cryptic Furanolide Pathway Revealed in <i>Nodularia</i> sp. NIES-3585. [PDF]

ACS Synth Biol
D'Agostino PM, de Castro RR, Uka V, Saurav K, Kriukova Y, Milzarek TM, Sester A, Schneider MP, Gulder TAM.   +8 more
europepmc   +1 more source

SSR4 sustains Tertiary Lymphoid Structures by Regulation Quality Control of N‐linked Glycosylation During B‐cell Differentiation Into Plasmacyte in Colorectal Cancer

Advanced Science, EarlyView.
SSR4, a TRAP component induced in B cells, governs BAFFR N‐glycosylation via DDOST to sustain NF‐κB signaling, B‐cell differentiation, and TLS maturation. Its loss impairs anti‐tumor immunity, while overexpression improves antibody glycosylation and ADCC, revealing a critical regulator for cancer immunotherapy.
Wei Zhao, Youcai Zhao, Haiyang Li, Bowen Yang, Siyan Lu, Xueting Fu, Caixia Zhang, Yirong Chen, Xiaofeng Bian, Xinghua Ma, Xiaobing Yang, Bin Wang, Yuan Fang, Lulu Yang, Yelin Zhao, Shuli Zhao   +15 more
wiley   +1 more source

Discovery of unprecedented prenylated indole piperazines and pyrazines through cryptic biosynthetic gene cluster heterologous expression. [PDF]

Nat Prod Bioprospect
Zha Z, He D, Song J, Guan Z, Han J, Liu C, Wang X, Zhu Y, Zhu H, Ye W, Li Q, Zhang Y, Zhou Y.   +12 more
europepmc   +1 more source