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A gene cluster of the ochratoxin A biosynthetic genes inPenicillium
Mycotoxin Research, 2006A putative ochratoxin A (OTA) biosynthetic gene cluster inP. nordicum has been identified. The first part of the gene cluster is located on a DNA fragment of 10 kb in length and harbours three genes. A gene with high homology to an alkaline serine protease gene (accession number AY557343), which represents the upstream border of the cluster ...
R, Geisen +2 more
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Expression of Cyanobacterial Biosynthetic Gene Clusters in Escherichia coli
2022Cyanobacteria represent an attractive source of natural bioactive compounds, ranging from sunscreens to cancer treatments. While many biosynthetic gene clusters (BGCs) that encode cyanobacterial natural products are known, the slow growth and lack of genetic tools in the native producers hampers their modification, characterization, and large-scale ...
Alescia, Cullen +2 more
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Defense-related phenylpropanoid biosynthetic gene clusters in rice
Science Bulletin, 2022Guy, Polturak, Anne, Osbourn
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Genome Mining for Actinomycete Biosynthetic Gene Clusters
2018Whole-genome sequencing has shown that the large (8-12 Mbp) genomes of Streptomyces and allied genera of Gram-positive filamentous bacteria house a rich and previously underestimated repertoire of gene clusters for biosynthesis of specialised metabolites, including antibiotics, immunosuppressants and anticancer compounds.
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Cancer epigenetics in clinical practice
Ca-A Cancer Journal for Clinicians, 2023Veronica Davalos, Manel Esteller
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Horizontal gene transfer and adaptive evolution in bacteria
Nature Reviews Microbiology, 2021Brian J Arnold, William P Hanage
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Beyond horizontal gene transfer: the role of plasmids in bacterial evolution
Nature Reviews Microbiology, 2021Jerónimo Rodríguez-Beltrán +2 more
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