Results 1 to 10 of about 202,591 (301)
Genome mining as a biotechnological tool for the discovery of novel biosynthetic genes in lichens. [PDF]
Front Fungal Biol, 2022 Natural products (NPs) and their derivatives are a major contributor to modern medicine. Historically, microorganisms such as bacteria and fungi have been instrumental in generating drugs and lead compounds because of the ease of culturing and ...
Singh G, Dal Grande F, Schmitt I.
europepmc +7 more sources
Diversity of Bacterial Biosynthetic Genes in Maritime Antarctica [PDF]
Microorganisms, 2020 Bacterial natural products (NPs) are still a major source of new drug leads. Polyketides (PKs) and non-ribosomal peptides (NRP) are two pharmaceutically important families of NPs and recent studies have revealed Antarctica to harbor endemic polyketide ...
Adriana Rego +6 more
doaj +6 more sources
Repression of ZCT1, ZCT2 and ZCT3 affects expression of terpenoid indole alkaloid biosynthetic and regulatory genes [PDF]
PeerJ, 2021 Terpenoid indole alkaloids (TIAs) include several valuable pharmaceuticals. As Catharanthus roseus remains the primary source of these TIA pharmaceuticals, several research groups have devoted substantial efforts to increase production of these compounds
Chun Yao Li, Susan I. Gibson
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Origin of saxitoxin biosynthetic genes in cyanobacteria. [PDF]
PLoS ONE, 2009 BACKGROUND:Paralytic shellfish poisoning (PSP) is a potentially fatal syndrome associated with the consumption of shellfish that have accumulated saxitoxin (STX). STX is produced by microscopic marine dinoflagellate algae.
Ahmed Moustafa +5 more
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Molecules, 2015 Glucosinolates are anti-carcinogenic, anti-oxidative biochemical compounds that defend plants from insect and microbial attack. Glucosinolates are abundant in all cruciferous crops, including all vegetable and oilseed Brassica species.
Go-Eun Yi +6 more
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Lipid biosynthetic genes and a ribosomal protein gene are cotranscribed [PDF]
FEBS Letters, 1995 By using insertional mutagenesis we demonstrated that the rpmF gene encoding ribosomal protein L32, the plsX gene encoding a protein involved in membrane lipid synthesis and several fatty acid biosynthetic genes (fabH, fabD and fabG) are cotranscribed.
Podkovyrov, Sergey, Larson, Timothy J.
openaire +4 more sources
The tylosin-biosynthetic genes of Streptomyces fradiae [PDF]
Antonie van Leeuwenhoek, 2001 The tylosin-biosynthetic (tyl) gene cluster occupies about 1% of the genome of Streptomycesfradiae and includes at least 43 open reading frames. In addition to structural genes required for tylosin production, the tyl cluster contains three resistance determinants and several regulatory genes.
E, Cundliffe +5 more
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Photoperiod and water-deficient conditions differentially regulate structural flavonoid biosynthetic genes in peanuts [PDF]
Journal of Plant Interactions, 2022 Peanut (Arachis hypogaea L.) harbors a plethora of flavonoids that impart its health-promoting properties. To understand its biosynthesis and accumulation, a comparative expression analysis of flavonoid biosynthetic genes encoding enzymes responsible for
Maryam Khan +9 more
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Molecules, 2016 Glucosinolates are the biochemical compounds that provide defense to plants against pathogens and herbivores. In this study, the relative expression level of 48 glucosinolate biosynthesis genes was explored in four morphologically-different cabbage ...
Arif Hasan Khan Robin +6 more
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Manipulation of hormone biosynthetic genes in transgenic plants [PDF]
Current Opinion in Biotechnology, 2000 Modification of plant hormone biosynthesis through the introduction of bacterial genes is a natural form of genetic engineering, which has been exploited in numerous studies on hormone function. Recently, biosynthetic pathways have been largely elucidated for most of the plant hormone classes, and genes encoding many of the enzymes have been cloned ...
P, Hedden, A L, Phillips
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