Results 21 to 30 of about 1,901,617 (293)
Investigating the biosynthesis of heam d1 in pseudomonas aeruginosa: a cofactor for dissimilatory nitrite reductase. [PDF]
, 2010 PhDHaem d1 is a modified tetrapyrrole unique to the periplasmic enzyme nitrite reductase where it acts in catalysing the reduction of nitrite (NO2 -) to nitric oxide (NO), as part of denitrification.
Parmar-Bhundia, Vina
core +4 more sources
Frontiers in Microbiology, 2017 The genus Streptomyces under phylum actinobacteria has been recognized as a prolific source for the production of bioactive secondary metabolites. An actinobacterial strain designated as DST103 isolated from a wetland fresh water sediment of Tamdil Lake,
Zothanpuia +6 more
doaj +1 more source
Microbial Cell Factories, 2021 Background Norvancomycin has been widely used in clinic to treat against MRSA (Methicillin-resistant Staphylococcus aureus) and MRSE (Methicillin-resistant Staphylococcus epidermidis) infections in China.
Xingxing Li +9 more
doaj +1 more source
Identification of target genes of the bZIP transcription factor OsTGAP1, whose overexpression causes elicitor-induced hyperaccumulation of diterpenoid phytoalexins in rice cells. [PDF]
PLoS ONE, 2014 Phytoalexins are specialised antimicrobial metabolites that are produced by plants in response to pathogen attack. Momilactones and phytocassanes are the major diterpenoid phytoalexins in rice and are synthesised from geranylgeranyl diphosphate, which is
Koji Miyamoto +8 more
doaj +1 more source
In silico methods for linking genes and secondary metabolites: The way forward
Synthetic and Systems Biotechnology, 2016 In silico methods for linking genomic space to chemical space have played a crucial role in genomics driven discovery of new natural products as well as biosynthesis of altered natural products by engineering of biosynthetic pathways.
Shradha Khater +2 more
doaj +1 more source
Scientific Reports, 2022 Sulfur is an essential element required for plant growth and development, physiological processes and stress responses. Sulfur-encoding biosynthetic genes are involved in the primary sulfur assimilation pathway, regulating various mechanisms at the gene,
Muhammad-Redha Abdullah-Zawawi +5 more
doaj +1 more source
Mining microbial genomes for new natural products and biosynthetic pathways [PDF]
, 2008 Analyses of microbial genome sequences have revealed numerous examples of ‘cryptic’ or ‘orphan’ biosynthetic gene clusters, with the potential to direct the production of novel, structurally complex natural products.
G. L. Challis, Challis, Gregory L.
core +1 more source
Реконструкція філогенії кластерів генів біосинтезу глікопептидів
Фактори експериментальної еволюції організмів, 2017 Aim. In current study we have endeavored to analyze the phylogeny of 18 sequenced glycopeptide biosynthetic gene clusters. Methods. Standard methods of phylogenetic reconstruction were used in this research. Results. We have created sets of conservative
O. S. Yushchuk +3 more
doaj +1 more source
A Candidate Gene Cluster for the Bioactive Natural Product Gyrophoric Acid in Lichen-Forming Fungi
Microbiology Spectrum, 2022 Natural products of lichen-forming fungi are structurally diverse and have a variety of medicinal properties. Despite this, they have limited implementation in industry mostly because the corresponding genes are unknown for most of their natural products.
Garima Singh +6 more
doaj +1 more source
Whole-genome sequence analysis of penitrem A-producing Penicillium crustosum isolated from pears: secondary metabolite biosynthesis [PDF]
PeerJBackground Penitrem A is a toxic secondary metabolite (SM) produced by Penicillium crustosum (P. crustosum) on various foods such as nuts, dairy products, and fruits. However, the biosynthetic gene clusters (BGCs) responsible for SMs including penitrem A
Sheng Ming Gao +2 more
doaj +2 more sources