Results 111 to 120 of about 202,591 (301)

Investigating the biosynthesis of heam d1 in pseudomonas aeruginosa: a cofactor for dissimilatory nitrite reductase. [PDF]

open access: yes, 2010
PhDHaem d1 is a modified tetrapyrrole unique to the periplasmic enzyme nitrite reductase where it acts in catalysing the reduction of nitrite (NO2 -) to nitric oxide (NO), as part of denitrification.
Parmar-Bhundia, Vina
core  

Screening and Transcriptional Analysis of Polyketide Synthases and Non-ribosomal Peptide Synthetases in Bacterial Strains From Krubera–Voronja Cave

open access: yesFrontiers in Microbiology, 2019
Identification of novel bioactive compounds represents an important field in modern biomedical research. Microorganisms of the underexplored environments, such as deserts, hot springs, oceans, and caves are highly promising candidates for screening such ...
Dominykas Bukelskis   +6 more
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Genome-based analysis of biosynthetic aminotransferase genes of Corynebacterium glutamicum [PDF]

open access: yes, 2003
McHardy AC, Tauch A, Rückert C, Pühler A, Kalinowski J. Genome-based analysis of biosynthetic aminotransferase genes of Corynebacterium glutamicum. J Biotechnol.
Rückert, Christian ; https://orcid.org/   +4 more
core   +1 more source

Interplay Between Ribosomal Gene Deficiency and Calorie Restriction in Shaping Yeast Biosynthetic Capacity

open access: yesCells
Biosynthetic capacity, particularly in protein production, significantly influences cells’ physiological efficiency and their ability to proliferate.
Roman Maslanka, Renata Zadrag-Tecza
doaj   +1 more source

Monasone Naphthoquinone Biosynthesis and Resistance in Monascus Fungi

open access: yesmBio, 2020
Despite the important biological activities of natural product naphthoquinones, the biosynthetic pathways of and resistance mechanisms against such compounds remain poorly understood in fungi.
Mu Li   +7 more
doaj   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

open access: yesFEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey   +4 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Differential effect of environmental conditions on the growth and regulation of the fumonisin biosynthetic gene FUM1 in the maize pathogens and fumonisin producers Fusarium verticillioides and Fusarium proliferatum [PDF]

open access: yes, 2010
The effects of ecophysiological factors, temperature and solute potential, on both the growth and the regulation of the fumonisin biosynthetic FUM1 gene were studied and compared in one isolate each of the two closely related fumonisin-producing and ...
Magan, Naresh   +3 more
core   +1 more source

Identification and expression analysis of strigolactone biosynthetic and signaling genes reveal strigolactones are involved in fruit development of the woodland strawberry (Fragaria vesca)

open access: yesBMC Plant Biology, 2019
Background The development and ripening of fresh fruits is an important trait for agricultural production and fundamental research. Almost all plant hormones participate in this process.
Han Wu   +9 more
doaj   +1 more source

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