Results 51 to 60 of about 1,901,617 (293)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

In silico analyses of maleidride biosynthetic gene clusters

Fungal Biology and Biotechnology, 2022
Maleidrides are a family of structurally related fungal natural products, many of which possess diverse, potent bioactivities. Previous identification of several maleidride biosynthetic gene clusters, and subsequent experimental work, has determined the ‘
Katherine Williams, Kate M. J. de Mattos-Shipley, Christine L. Willis, Andrew M. Bailey   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Functional conservation of coenzyme Q biosynthetic genes among yeasts, plants, and humans. [PDF]

PLoS ONE, 2014
Coenzyme Q (CoQ) is an essential factor for aerobic growth and oxidative phosphorylation in the electron transport system. The biosynthetic pathway for CoQ has been proposed mainly from biochemical and genetic analyses of Escherichia coli and ...
Kazuhiro Hayashi, Yuki Ogiyama, Kazumasa Yokomi, Tsuyoshi Nakagawa, Tomohiro Kaino, Makoto Kawamukai   +5 more
doaj   +1 more source

Lipid biosynthetic genes and a ribosomal protein gene are cotranscribed [PDF]

FEBS Letters, 1995
By using insertional mutagenesis we demonstrated that the rpmF gene encoding ribosomal protein L32, the plsX gene encoding a protein involved in membrane lipid synthesis and several fatty acid biosynthetic genes (fabH, fabD and fabG) are cotranscribed.
Podkovyrov, Sergey, Larson, Timothy J.
openaire   +2 more sources

Molecular evolution of paclitaxel biosynthetic genes TS and DBAT of Taxus species

, 2009
Evolutionary patterns of sequence divergence were analyzed in genes from the conifer genus Taxus (yew), encoding paclitaxel biosynthetic enzymes taxadiene synthase (TS) and 10-deacetylbaccatin III-10 beta-O-acetyltransferase (DBAT).
Huang, B. L., 黄本立, Hao, Da Cheng, 杨凌, Yang, L., Huang, Beili, Hao, D. C., Yang, Ling   +7 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Exogenous Methyl Jasmonate and Salicylic Acid Induce Subspecies-Specific Patterns of Glucosinolate Accumulation and Gene Expression in Brassica oleracea L.

Molecules, 2016
Glucosinolates have anti-carcinogenic properties. In the recent decades, the genetics of glucosinolate biosynthesis has been widely studied, however, the expression of specific genes involved in glucosinolate biosynthesis under exogenous phytohormone ...
Go-Eun Yi, Arif Hasan Khan Robin, Kiwoung Yang, Jong-In Park, Byung Ho Hwang, Ill-Sup Nou   +5 more
doaj   +1 more source

Polyhydroxyalkanoate biosynthesis in Bacillus cereus SPV under varied limiting conditions and an insight into the biosynthetic genes involved

, 2008
Aims: A new strain of Bacillus, Bacillus cereus SPV, was found to be capable of using a wide range of carbon sources for the production of polyhydroxyalkanoates (PHAs) (Valappil et al. 2007b).
Roy, I., Bucke, C., Rai, R., Valappil, S.P.   +3 more
core   +1 more source

Identification and Functional Characterization of Genes Encoding Omega-3 Polyunsaturated Fatty Acid Biosynthetic Activities from Unicellular Microalgae [PDF]

, 2013
In order to identify novel genes encoding enzymes involved in the biosynthesis of nutritionally important omega-3 long chain polyunsaturated fatty acids, a database search was carried out in the genomes of the unicellular photoautotrophic green alga ...
Johnathan A. Napier, Olga Sayanova, Sayanova, O. V., Johnathan Napier, Napier, J. A., Vaezi, R., Royah Vaezi   +6 more
core   +1 more source