Results 1 to 10 of about 742 (113)

Pituitary Neurolobectomy induces sustained hypotension in male Wistar rats and normalizes blood pressure in male spontaneously hypertensive rats. [PDF]

Physiol Rep
Abstract Arginine vasopressin is primarily recognized as an osmoregulatory hormone; however, its contribution to vascular tone and blood pressure regulation under basal and hypertensive conditions remains debated. This study examined the effects of vasopressin deficiency induced by neurointermediate pituitary lobectomy in Wistar and spontaneously ...
Villanueva-Rodríguez GM, Bobadilla NA, Quintanar JL, Rivera-Cerecedo CV, Chavira-Ramírez DR, Kovacs K, Quintanar-Stephano A.   +6 more
europepmc   +2 more sources

Lymphoid Organs Remodeling in Non-Obese Diabetic Goto-Kakizaki Rats Immunized With SARS-CoV-2 Antigens. [PDF]

FASEB J
The Goto‐Kakizaki rat, a non‐obese model of type 2 diabetes mellitus (T2DM), exhibits lymphoid organ remodeling, including baseline thymic involution and splenic white pulp reorganization. Following completion of a three‐dose SARS CoV‐2 antigen immunization protocol, anti‐Spike IgG levels were significantly increased despite these structural changes ...
Pereira SA, Lazzarin MC, Dagli MLZ, Távora BCLF, Mauro EFL, Santoro ML, Vessoni SCS, Gonçalves LRC, Sotoyama MS, Oliveira RDN, Mattaraia VGM, Curi R.   +11 more
europepmc   +2 more sources

Determinación de parámetros bioquímicos de animales del Bioterio de la Facultad de Ciencias Químicas de la Universidad Nacional de Asunción

Revista de la Sociedad Científica del Paraguay, 2023
Animales de laboratorio criados en diferentes Bioterios muestran variaciones en sus características fisiológicas debido a la dieta, manejo, estado de salud, edad, vías de toma de muestras y otros factores.
Wilfrido Arrúa Báez, Juan Rafael Centurión Quintana, Yenny Montalbetti Moreno, Olga Yolanda Heinichen Almada   +3 more
doaj   +1 more source

Minor Changes in Daily Rhythms Induced by a Skeleton Photoperiod Are Associated with Increased Adiposity and Glucose Intolerance

Advanced Biology, Volume 7, Issue 11, November 2023., 2023
Feeding during the day promotes metabolic impairments in rats. Here, the contribution of light to day‐feeding impairments is investigated by eliminating light with a skeleton photoperiod. Surprisingly, the skeleton photoperiod shifts metabolic rhythms and is also associated with metabolic issues, indicating that, in addition to proper feeding schedules,
Rebeca Méndez‐Hernández, Valentina S. Rumanova, Mara A. Guzmán‐Ruiz, Ewout Foppen, Rodrigo Moreno‐Morton, Gabriela Hurtado‐Alvarado, Carolina Escobar, Andries Kalsbeek, Ruud M. Buijs   +8 more
wiley   +1 more source

Evaluations of Anticancer Effects of Combinations of Cisplatin and Tirucallane‐Type Triterpenes Isolated from Amphipterygium adstringens (Schltdl).

Chemistry &Biodiversity, Volume 20, Issue 10, October 2023., 2023
Abstract The cytotoxic activity of combinations of masticadienonic (AMD) or 3αOH‐hydroxy‐masticadienonic (3αOH‐AMD) acids with cisplatin (CDDP) was evaluated against PC3 prostate and HCT116 colon cancer cell lines. Combinations A (half the IC50 value), B (IC50 value), and C (twice the IC50 value) were tested at a 1 : 1 ratio.
Lidia Díaz‐Sánchez, Alejandro Zentella‐Dehesa, Víctor Alberto Castro‐Torres, Noemi Silva‐Jiménez, Nadia Judith Jacobo‐Herrera, Mariano Martínez‐Vázquez   +5 more
wiley   +1 more source

Adiponectin reverses β‐Cell damage and impaired insulin secretion induced by obesity

Aging Cell, Volume 22, Issue 6, June 2023., 2023
Incubation of β‐cells with sera or plasma from obese rats and humans hampers mitochondrial oxidative phosphorylation and glucose‐stimulated insulin secretion (GSIS) relative to sera and plasma from lean rats and humans. Adiponectin, found at elevated levels in lean subjects, supports β‐cell function on its own, in the absence of sera, and also reverses
Ana Cláudia Munhoz, Julian D. C. Serna, Eloisa Aparecida Vilas‐Boas, Camille C. Caldeira da Silva, Tiago G. Santos, Francielle C. Mosele, Sergio L. Felisbino, Vilma Regina Martins, Alicia J. Kowaltowski   +8 more
wiley   +1 more source

Genes regulated by DNA methylation are involved in distinct phenotypes during melanoma progression and are prognostic factors for patients

Molecular Oncology, Volume 16, Issue 9, Page 1913-1930, May 2022., 2022
Epigenetic alterations related to aberrant gene expression are important regulators of malignant transformation and melanoma progression. Here, we integrated transcriptome and methylome data from a linear model of murine melanoma progression and identified promoter and/or gene body DNA methylation profiles that induced gene expression changes related ...
Debora D’Angelo Papaiz, Flávia Eichemberger Rius, Ana Luísa Pedroso Ayub, Clarice S. Origassa, Hemant Gujar, Diogo de Oliveira Pessoa, Eduardo Moraes Reis, Jérémie Nsengimana, Julia Newton‐Bishop, Christopher E. Mason, Daniel J. Weisenberger, Gangning Liang, Miriam Galvonas Jasiulionis   +12 more
wiley   +1 more source

Treatment with Distinct Antibiotic Classes Causes Different Pulmonary Outcomes on Allergic Airway Inflammation Associated with Modulation of Symbiotic Microbiota

Journal of Immunology Research, Volume 2022, Issue 1, 2022., 2022
Background. Asthma is a chronic pulmonary disease that affects about 300 million people worldwide. Previous studies have associated antimicrobial use with allergies, but the real impact of antibiotics on asthma is still elusive. We investigated the potential impact of amoxicillin (Amox), trimethoprim/sulfamethoxazole (TMP/SMX), and metronidazole (Metro)
Gregório Grama Cavalcante, Anna Gabriella Guimarães, Camila Pereira Queiroz-Glauss, Marcela Helena Gonçalves Pereira, Angélica Samer Lallo Dias, Laila Sampaio Horta, Jamil Silvano de Oliveira, Silvia Dantas Cangussú, Paula Prazeres Magalhães, Remo Castro Russo, H. C. Santiago, Keshav Raj Paudel   +11 more
wiley   +1 more source

Videocâmeras em biotérios de experimentação: importante ferramenta no controle da contaminação ambiental na microbiota de camundongos

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2015
O objetivo do presente estudo foi verificar a influência da contaminação ambiental na microbiota dos animais utilizados em experimentação, usando-se videocâmera como ferramenta de controle, a partir da comparação de dois biotérios de experimentação ...
C.A. Muller, S. Ramos, A.O. Saisse, N.R.P. Almosny   +3 more
doaj   +1 more source

Effects of Low Protein‐High Carbohydrate Diet during Early and Late Pregnancy on Respiratory Quotient and Visceral Adiposity

Oxidative Medicine and Cellular Longevity, Volume 2022, Issue 1, 2022., 2022
Background. Low Protein‐High Carbohydrate (LPHC) diet during pregnancy is considered a nutritional and health problem related to the development of maternal metabolic alterations, such as fatty liver and obesity in the perinatal and postnatal period. It is known that increase in visceral adiposity tissue (VAT) modulates maternal metabolic rate, with ...
Mónica Navarro-Meza, Mauricio Díaz-Muñoz, Perla Belén García-Solano, Raquel Cobián-Cervantes, Éricka A. de los Ríos-Arellano, Felipe Santoyo Telles, Mariela Camacho-Barrón, Ilaria Peluso   +7 more
wiley   +1 more source