Results 211 to 220 of about 467,470 (351)

BIOTIN SULFOXIDE

Journal of Biological Chemistry, 1954
openaire   +2 more sources

A Novel FGFR3‐Targeting Antibody‐Drug Conjugate Induces Tumor Cell Apoptosis through the cGAS–STING Pathway in Bladder Cancer

Advanced Science, EarlyView.
LZU‐WZLYCS01 is a novel FGFR3‐targeting ADC for bladder cancer with 7‐ethyl‐9‐fluorocamptothecin (A2) as its cytotoxic payload. LZU‐WZLYCS01 intracellularly releases A2, which targets MAD2L1 to activate the cGAS‐STING pathway and induce tumor cell apoptosis.
Shu Cui, Xiongfei Luo, Guangrui Fan, Jingqi Jiang, Yingru Wang, Enguang Yang, Jinpeng Ma, Ze Zhang, Yuhan Wang, Juan Wang, Dengtuo Wang, Hanzhang Wang, Liang Cheng, Junqiang Tian, Zhilong Dong, Yingqian Liu, Zhiping Wang   +16 more
wiley   +1 more source

Profiling the Cellular Surfaceome by Furan-Based Protein Biotinylation. [PDF]

J Proteome Res
Fernández E, Miret-Casals L, Madder A, Gevaert K.   +3 more
europepmc   +1 more source

Geometrically Encoded Positioning of Introns, Intergenic Segments, and Exons in the Human Genome

Advanced Science, EarlyView.
This study introduces a new hypothesis: exons, introns, and intergenic segments are non‐random projections of the functional layers of 3D structure of chromatin packing domains. Evidence is presented that this “geometric code” may encode volumetric structure, reconciling epigenetic patterns, correlates with oncogenic mutations, acting as a potential ...
Luay M. Almassalha, Kyle L. MacQuarrie, Marcelo Carignano, Cody L. Dunton, Ruyi Gong, Joe Ibarra, Lucas M. Carter, Wing Shun Li, Rikkert Nap, Parambir S. Dulai, Igal Szleifer, Vadim Backman   +11 more
wiley   +1 more source

Optimizing multifunctional fluorescent ligands for intracellular labeling. [PDF]

Proc Natl Acad Sci U S A
Kumar P, Vevea JD, Tkachuk AN, Campbell KR, Watson ET, Ayala AX, Grimm JB, Chapman ER, Solecki DJ, Lavis LD.   +9 more
europepmc   +1 more source

Biotin-decorated all-HPMA polymeric micelles for paclitaxel delivery

, 2020
Yan Wang, Mies J. van Steenbergen, Nataliia Beztsinna, Yang Shi, Twan Lammers, Cornelus F. van Nostrum, Wim E. Hennink   +6 more
openalex   +2 more sources

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

Advanced Science, EarlyView.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha, Sofya Kosmynina, Amandine Verocq, Keremsah Ozen, Ines Tekia, Hugo Bussy, Marie Ramirez, Dima Sabbah, Chloe Goemans, Valerie Vandenbempt, Esteban N. Gurzov, Sumeet Pal Singh, Nicolas Baeyens   +12 more
wiley   +1 more source

Target cell cortical tension regulates macrophage trogocytosis. [PDF]

Nat Cell Biol
Cornell CE, Chorlay A, Krishnamurthy D, Martin NR, Baldauf L, Fletcher DA.   +5 more
europepmc   +1 more source

Holocarboxylase synthetase regulates expression of biotin transporters by chromatin remodeling events at the SMVT locus

, 2007
Michael Gralla, Gabriela Camporeale, Janos Zempleni   +2 more
openalex   +1 more source

The effect of N-bromosuccinimide on the sub-unit structure of avidin and its complexes with biotin [PDF]

, 1968
N. M. Green, M. E. Ross
openalex   +1 more source