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The biotransformation of nitroglycerin
Biochemical Pharmacology, 1965Abstract The transformation of nitroglycerin (NG) was accomplished by the formation of 1,2- and 1,3-dinitroglycerin. The dinitrates were resistant to further degradation and appeared as the urinary metabolites after the administration of NG. The dinitroglycerins were less active coronary vasodilators and blood pressure depressants than NG.
John C. Krantz, Philip Needleman
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In-vivo biotransformation of citrus functional components and their effects on health
Critical reviews in food science and nutrition, 2020Citrus, one of the most popular fruits worldwide, contains various functional components, including flavonoids, dietary fibers (DFs), essential oils (EOs), synephrines, limonoids, and carotenoids.
A. Karn +8 more
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Critical Reviews in Biotechnology, 2020
Flavonoids, especially flavanones, flavones and polymethoxyflavones (PMFs) are distinctive bioactive compounds of Citrus fruits. Citrus peel and juice by-products potentially represent rich sources of these Citrus flavonoids that exhibit a myriad of ...
Z. T. Shakour, Nesrin M. Fayek, M. Farag
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Flavonoids, especially flavanones, flavones and polymethoxyflavones (PMFs) are distinctive bioactive compounds of Citrus fruits. Citrus peel and juice by-products potentially represent rich sources of these Citrus flavonoids that exhibit a myriad of ...
Z. T. Shakour, Nesrin M. Fayek, M. Farag
semanticscholar +1 more source
Environmental Science and Technology, 2019
The brominated flame retardant decabromodiphenyl ethane (DBDPE), an alternative to decabrominated diphenyl ether (BDE209), has become a widespread environmental contaminant, but its possible toxic effects to wildlife remain unknown.
Xiaocheng Wang +8 more
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The brominated flame retardant decabromodiphenyl ethane (DBDPE), an alternative to decabrominated diphenyl ether (BDE209), has become a widespread environmental contaminant, but its possible toxic effects to wildlife remain unknown.
Xiaocheng Wang +8 more
semanticscholar +1 more source
Biotransformations of Steroids
Critical Reviews in Biotechnology, 1988Different types of microbiological transformation of steroids are reviewed, with special attention given to bioconversions applied in the manufacturing of steroid hormones, i.e., 11 alpha- 11 beta-, 16 alpha-, 17 alpha-hydroxylations and 1-dehydrogenation.
Leon Sedlaczek, Leland L. Smith
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Biotransformation of alkaloids
2001Biotransformations of alkaloids over the last decade have continued to encompass a wide variety of substrates and enzymes. The elucidation of novel alkaloid biosynthetic and catabolic pathways will continue to furnish new biocatalysts for the synthetic organic chemist.
Deborah A. Rathbone +2 more
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Biotransformations with Peroxidases
1999Enzymes are chiral catalysts and are able to produce optically active molecules from prochiral or racemic substrates by catalytic asymmetric induction. One of the major challenges in organic synthesis is the development of environmentally acceptable chemical processes for the preparation of enantiomerically pure compounds, which are of increasing ...
Dietmar Häring +6 more
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Clinical Pharmacology & Therapeutics, 2014
The field of clinical pharmacology and therapeutics spans a wide spectrum of research areas involving human subjects at both individual and population levels. One of the key concepts relevant to all of these research areas is biotransformation of drug molecules, which can be defined as the chemical modification of drugs within an organism.
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The field of clinical pharmacology and therapeutics spans a wide spectrum of research areas involving human subjects at both individual and population levels. One of the key concepts relevant to all of these research areas is biotransformation of drug molecules, which can be defined as the chemical modification of drugs within an organism.
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Biotransformations of Explosives
Biotechnology and Genetic Engineering Reviews, 2001(2001). Biotransformations of Explosives. Biotechnology and Genetic Engineering Reviews: Vol. 18, No. 1, pp. 171-217.
Susan J. Rosser +2 more
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Biotransformations with nitrilases
Current Opinion in Chemical Biology, 2010The range of possible nitrilase applications has been recently broadened but in most cases the parameters of the reactions need to be improved to establish viable industrial processes. To achieve this goal, several methods have been used, primarily in screening for enzymes from new sources, enzyme improvement, substrate structure modification, medium ...
Vladimir Kren, Ludmila Martínková
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