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Biotransformation of Neuropeptides

Neuroendocrinology, 1984
The ability of neuropeptides to act as precursors for smaller, biologically active fragments is discussed in terms of their biotransformation. This process may involve cleavage of the parent peptide by peptidase enzymes to produce shorter polypeptides with defined biological activity, though other enzymic processes such as sulphation and acetylation ...
E.C. Griffiths, John R. McDermott
openaire   +2 more sources

Biotransformation of Phencyclidine

Drug Metabolism Reviews, 1985
PCP is metabolized extensively in the body via a variety of metabolic routes. Biotransformation is a major mechanism of PCP elimination in humans and termination of PCP action in mice. In general, PCP metabolites are less active pharmacologically than PCP itself.
Edward F. Domino   +1 more
openaire   +3 more sources

Biotransformation of Drugs

1978
During the past several years it has become generally accepted that the incidence of adverse reactions to drugs in patients increase with age (1–3). However, the reasons for the increased incidence are frequently obscure and often differ with the drug.
James R. Gillette, Jack A. Hinson
openaire   +3 more sources

Digoxin biotransformation

Clinical Pharmacology and Therapeutics, 1984
Serum digoxin and metabolites were assayed in plasma and urine by HPLC in 10 dialysis-dependent patients with end-stage renal failure (group I) and in five patients with comparatively normal renal function (group II) after ingestion of 150 muCi 3H-digoxin-12 alpha.
M H, Gault   +6 more
openaire   +2 more sources

Biotransformations

2011
Biotransformations using enzymes and whole microbial cells have been used for centuries to produce foods and beverages. However, only in the last century we have developed methods to understand and improve biocatalyst stability and productivities. Engineering and directed evolution of enzymes have enhanced enzymatic activity and increased the number of
C.C.C.R. de Carvalho, M.M.R. da Fonseca
openaire   +2 more sources

Biotransformation of Plant‐Derived Phenolic Acids

Biotechnology Journal, 2018
Phenolic acids are abundant biomass feedstock that can be derived from the processing of lignin or other byproducts from agro‐industrial waste. Although phenolic acids such as p‐hydroxybenzoic acid, p‐coumaric acid, caffeic acid, vanillic acid, cinnamic ...
R. Tinikul   +3 more
semanticscholar   +1 more source

Biotransformation of Sevoflurane

Anesthesia & Analgesia, 1995
Several characteristics of sevoflurane biotransformation are apparent from the preceding investigations. Metabolism is rapid, with fluoride and HFIP appearing in plasma within minutes after the start of sevoflurane administration (38-40,51). Peak plasma fluoride concentrations generally occur within approximately 1 h after the termination of ...
openaire   +3 more sources

Digoxigenin biotransformation

Clinical Pharmacology and Therapeutics, 1982
Two healthy subjects took 3H-digoxigenin-12 alpha and unlabeled digoxigenin. Metabolites were assayed by high-pressure liquid chromatography (HPLC) in serum and urine. Of the tritium activity in the serum at 30 min, less than 26% chromatographed with digoxigenin; the rest chromatographed as metabolites, most of which were polar.
H, Gault   +3 more
openaire   +2 more sources

Biotransformation of sulfamethoxazole by microalgae: Removal efficiency, pathways, and mechanisms.

Water Research, 2022
Yuhao Chu   +5 more
semanticscholar   +1 more source

Ammonia Monooxygenase-Mediated Cometabolic Biotransformation and Hydroxylamine-Mediated Abiotic Transformation of Micropollutants in an AOB/NOB Coculture.

Environmental Science and Technology, 2018
Biotransformation of various micropollutants (MPs) has been found to be positively correlated with nitrification in activated sludge communities. To further elucidate the roles played by ammonia-oxidizing bacteria (AOB) and nitrite-oxidizing bacteria ...
Yaochun Yu   +5 more
semanticscholar   +1 more source

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