Results 151 to 160 of about 161,017 (342)

A Comprehensive Review of Probiotics in Alleviating Hyperuricemia: Mechanisms, Strain Engineering, and Food Applications

Food Bioengineering, EarlyView.
Screening and modification of probiotics that can efficiently reduce uric acid provide a new strategy for food‐grade hyperuricemia intervention. ABSTRACT Hyperuricemia has become one of the most prevalent global epidemics, significantly impacting both the economy and the health of individuals.
Le Wang, Qi Wu, Mengjia Zhang, Zifu Ni, Pengshuai Zhang, Siyuan Bai, Yibin Wang, Zhongke Sun   +7 more
wiley   +1 more source

Standardization and micromechanistic study of tetracycline adsorption by biochar

Biochar
Modification serves as an excellent approach to  enhancing the adsorption performance of biochar for tetracycline. Selective modification further allows the attainment of biochar materials that are not only more efficient but also cost-effective. However,
Xiaotong Zhang, Jinju Hou, Shudong Zhang, Tong Cai, Shujia Liu, Wenjin Hu, Qiuzhuo Zhang   +6 more
doaj   +1 more source

Fermentation‐Assisted Valorization: A Sustainable Strategy for Turning Fruit By‐Products Into Value‐Added Food Supplements

Food Frontiers, EarlyView.
ABSTRACT A substantial proportion of fresh fruit undergoes processing, resulting in underutilized fruit by‑products (FBPs) that are rich in dietary fiber and bioactive compounds. Recent FBP valorization trends demonstrate that fermentation significantly enhances microbiological, nutritional, and sensory attributes, yielding value‑added food supplements.
Abouzar Ghasemi, Salwa Karboune, Denis Groleau, Ismail Fliss   +3 more
wiley   +1 more source

Paraverrucsins A–F, Antifeedant, and Antiphytopathogenic Polyketides from Rhizospheric Paraphaeosphaeria verruculosa and Induced Bioactivity Enhancement by Coculturing with Host Plant Dendrobium officinale

ACS Omega, 2020
Ming Hu, Xue-Qiong Yang, Cui-Fang Wang, Tong-De Zhao, Dai-Li Wang, Ya-Bin Yang, Zhong-Tao Ding   +6 more
doaj   +1 more source

Biotransformation of anthelmintics in nematodes in relation to drug resistance

International Journal for Parasitology: Drugs and Drug Resistance
In all organisms, the biotransformation of xenobiotics to less toxic and more hydrophilic compounds represents an effective defense strategy. In pathogens, the biotransformation of drugs (used for their elimination from the host) may provide undesirable ...
Ondřej Vosála, Josef Krátký, Petra Matoušková, Nikola Rychlá, Karolína Štěrbová, Lucie Raisová Stuchlíková, Ivan Vokřál, Lenka Skálová   +7 more
doaj   +1 more source

Systemic Toxicity of L‐Mimosine in Rabbits: A Non‐Rodent Model for Safety Assessment

Journal of Applied Toxicology, EarlyView.
ABSTRACT L‐mimosine is a non‐protein amino acid primarily found in the Mimosoideae subfamily, with high concentrations in Leucaena leucocephala and Mimosa pudica. These plants are widely used in both human and animal nutrition, as well as in phytotherapeutic applications. While the toxic effects of L‐mimosine have been extensively studied in ruminants,
S. M. Ferreira, H. Zapparoli, C. S. Mussi, P. C. Maiorka, A. F. C. Andrade, S. L. Górniak, A. T. Gotardo   +6 more
wiley   +1 more source

Mimotope peptide modified pompon mum-like magnetic microparticles for precise recognition, capture and biotransformation analysis of rituximab in biological fluids

, 2023
Jiawen Yang, Aixuan Zhou, Min‐Yi Li, Qiaoxian He, Jingwei Zhou, Jacques Crommen, Wentao Wang, Zhengjin Jiang, Qiqin Wang   +8 more
openalex   +1 more source

Evaluation of Acephate Metabolites Generated by Zebrafish (Danio rerio) Using LC–HRMS and Metabolomics Approach

Journal of Applied Toxicology, EarlyView.
ABSTRACT Acephate is an organophosphate insecticide widely used. This pesticide can be metabolized into methamidophos, a molecule highly toxic. Both have demonstrated the ability to promote serious toxic effects on nontarget organisms and have been identified in surface waters around the world. Therefore, it is important to understand their behavior in
Mariana Laiz Silva de Lima, Lucas Rodrigues Cunha, Karina Taciana Santos Rubio, Maria Elvira Poleti Martucci   +3 more
wiley   +1 more source

Identification of Xenobiotic Biotransformation Products Using Mass Spectrometry-Based Metabolomics Integrated with a Structural Elucidation Strategy by Assembling Fragment Signatures [PDF]

, 2023
Yuan-Chih Chen, Hsin‐Yi Wu, Wei-Sheng Wu, Jen-Yi Hsu, Chih‐Wei Chang, Yuan-Han Lee, Pao‐Chi Liao   +6 more
openalex   +1 more source

Population Pharmacokinetic and Exposure‐Efficacy Analyses of Valbenazine in Patients with Huntington's Disease: Supporting Dose Selection for Chorea Management

The Journal of Clinical Pharmacology, EarlyView.
Abstract Valbenazine improved chorea in individuals with Huntington's disease compared to placebo in a phase 3, placebo‐controlled study (KINECT‐HD). Population pharmacokinetics (PK) and exposure–response (E–R) analyses focused on understanding the PK characteristics of valbenazine and its active metabolite, [+]‐α‐dihydrotetrabenazine ([+]‐α‐HTBZ), and
Hoa Q. Nguyen, Ryan L. Crass, Sunny Chapel, Han‐Yi Steve Kuan, Gordon Loewen, Satjit Brar   +5 more
wiley   +1 more source