Results 31 to 40 of about 164,185 (363)
Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 2022 Ruellia tuberosa (family Acanthaceae) is widely known in traditional medicine in Asian countries for the treatment of diabetes and other diseases. Its roots were demonstrated to possess a hypoglycemic ability in diabetic animal models. In this study, an
Dai M. CAO +2 more
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Application of nitroarene dioxygenases in the design of novel strains that degrade chloronitrobenzenes. [PDF]
, 2009 Widespread application of chloronitrobenzenes as feedstocks for the production of industrial chemicals and pharmaceuticals has resulted in extensive environmental contamination with these toxic compounds, where they pose significant risks to the health ...
Ju, Kou-San, Parales, Rebecca E
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Nature Communications, 2018 Achieving high titer yield and productivity of target chemicals in industrial organism depends on multidimensional pathway optimization. Here, the authors use a refined modular method called multidimensional heuristic process to improve production of ...
Congqiang Zhang +3 more
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Microorganisms, 2019 The potential of the plasma membrane (Δψ) regulates the electrochemical potential between the outer and inner sides of cell membranes. The opportunistic fungal pathogen, Candida albicans, regulates the membrane potential in response to ...
Jakub Suchodolski, Anna Krasowska
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Molecules, 2020 Cyanobacteria exhibit great biotechnological potential due to their capacity to produce compounds with various applicability. Volatile organic compounds (VOCs) possess low molecular weight and high vapor pressure.
Samuel Cavalcante do Amaral +4 more
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Characterization of porcine hepatic and intestinal drug metabolizing CYP450 : comparison with human orthologues from a quantitative, activity and selectivity perspective [PDF]
, 2019 Over the past two decades, the pig has gained attention as a potential model for human drug metabolism. Cytochrome P450 enzymes (CYP450), a superfamily of biotransformation enzymes, are pivotal in drug metabolism.
Croubels, Siska +7 more
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In vivo metabolism of ibuprofen in growing conventional pigs : a pharmacokinetic approach [PDF]
, 2019 The juvenile conventional pig has been suggested as a preclinical animal model to evaluate pharmacokinetic (PK), pharmacodynamic (PD), and safety parameters in children. However, a lot of developmental changes in pig physiology still need to be unraveled.
Croubels, Siska +3 more
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Cyanobacteria: A Promising Source of Antifungal Metabolites
Marine Drugs, 2023 Cyanobacteria are a rich source of secondary metabolites, and they have received a great deal of attention due to their applicability in different industrial sectors. Some of these substances are known for their notorious ability to inhibit fungal growth.
Samuel Cavalcante do Amaral +3 more
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Clinical Pharmacology & Therapeutics, 2014 The field of clinical pharmacology and therapeutics spans a wide spectrum of research areas involving human subjects at both individual and population levels. One of the key concepts relevant to all of these research areas is biotransformation of drug molecules, which can be defined as the chemical modification of drugs within an organism.
openaire +3 more sources
Asymmetric microbial conversion of (E)-2-benzylideneindan-1-one by the filamentous fungi Botrytis cinerea, Trichoderma viride, and Eutypa lata [PDF]
, 2011 The transformation of (E)-2-benzylideneindan-1-one 1 by the filamentous fungi Botrytis cinerea, Trichoderma viride, and Eutypa lata as biocatalysts was studied.
Aleu Casatejada, Josefina +2 more
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