Results 91 to 100 of about 3,953,785 (309)

Vision and Textuality in [PDF]

Este artículo analiza el conflicto entre las formas de representación visuales y textuales como tema central de la formación en Wilhelm Meisters Lehrjahre de Goethe.
Birth, Monica
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Pathways of the determinants of unfavourable birth outcomes in Kenya

, 2003
This paper explores the pathways of the determinants of unfavourable birth outcomes, such as premature birth, the size of the baby at birth, and Caesarean section deliveries in Kenya, using graphical loglinear chain models. The results show that a number
Diamond, Ian, Madise, Nyovani, Magadi, Monica, Smith, Peter   +3 more
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

« Si on peut vous éviter une balafre […], vous accouchez comme une fleur ! » : réguler l’usage de la césarienne à l’hôpital public dans la France contemporaine

Anthropologie & Santé
The rate of Cesarean sections in France has remained stable over the last twenty years, after a continuous increase until the 1990s. Based on observations made in a public hospital and interviews with health professionals and patients who have given ...
Maëlys Bar
doaj   +1 more source

ANN for Predicting Birth Weight [PDF]

, 2020
In this research, an Artificial Neural Network (ANN) model was developed and tested to predict Birth Weight. A number of factors were identified that may affect birth weight.
Mohammad, Shawwah, Suheil, Murshidy
core  

Growth, current size and the role of the 'reversal paradox' in the foetal origins of adult disease: an illustration using vector geometry [PDF]

, 2006
BACKGROUND Numerous studies have reported inverse associations between birth weight and a range of diseases in later life. These have led to the development of the 'foetal origins of adult disease hypothesis'. However, many such studies have only been
Ellison, G.T.H., Gilthorpe, M.S., Tu, Y-K.   +2 more
core   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Pregnancy outcomes among daycare employees in Finland

Scandinavian Journal of Work, Environment & Health, 2010
OBJECTIVE: The aim of this study was to investigate whether working as a daycare employee increases the risk of perinatal death, pre-term birth, low birth weight, smallness for gestational age, or congenital malformations.
Anita Riipinen, Markku Sallmén, Helena Taskinen, Aki Koskinen, Marja-Liisa Lindbohm   +4 more
doaj   +1 more source

Life, Birth and Death in Democritus. Atomistic Reflections Between Physics and Ethics

Peitho, 2017
The subject of life, birth and death constitutes one of the main topics in Democritus’ reflection on human questions. He seeks to understand what men think about the processes of birth and death and how they, accordingly, determine their behavior and ...
Miriam Campolina Diniz Peixoto
doaj   +1 more source