Results 121 to 130 of about 3,953,785 (309)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Journal of Perinatal Education, 2008 A young mother shares her story of normal birth at home. Her story includes a thank-you letter written to Ina May Gaskin, who shared her wisdom in her book, Ina May's Guide to Childbirth.
openaire +2 more sources
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
The Journal of Perinatal Education, 2011 In this column, Rachel Mann shares the story of the birth of her third daughter, Louisa. After a previous pregnancy loss, Mann chose to give birth to her third baby in a hospital with attending care from an obstetrician. In spite of the high-risk medical environment, she was able to have an unmedicated, powerful birth.
openaire +2 more sources
Medicine ScienceThe study seeks to assess the utility and informational quality of Instagram postings regarding water birth, an alternative birthing method recently gaining popularity. The two most used hashtags related to waterbirth have been selected: #waterbirth and #
Busra Sahin, Burcu Ozata
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Malthus Was Right After All: Poor Relief and Birth Rates in Southeastern England [PDF]
, 1989 The payment of child allowances to laborers with large families was widespread in early nineteenth-century England. This paper tests Thomas Malthus\u27s hypothesis that child allowances caused the birth rate to increase.
Boyer, George R
core +1 more source
Deciphering the fluctuations of high frequency birth rates
, 2018 Here the term "high frequency" refers to daily, weekly or monthly birth data. The fluctuations of daily birth numbers show a succession of spikes and dips which, at least at first sight, looks almost as random as white noise.
Herteliu, Claudiu +2 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source