Results 1 to 10 of about 448,876 (293)

Thalidomide and birth defects [PDF]

open access: yes, 2017
Apologies to the many papers we were unable to cite, due to space constraints. We thank Lynda Erskine, Shaunna Beedie and Chris Mahony for helpful discussions.
Diamond, Alex   +2 more
core   +1 more source

The changing epidemiology of syndactyly in Chinese newborns: a nationwide surveillance-based study

open access: yesBMC Pregnancy and Childbirth, 2023
Background Little is known about the epidemiologic features of syndactyly (SD) in Chinese newborns. Methods Using 2007–2019 data from the Chinese Birth Defects Monitoring Network, we conducted a prevalence analysis on overall, isolated and associated ...
Zhi-Yu Chen   +7 more
doaj   +1 more source

Birth prevalence of neural tube defects and orofacial clefts in India: a systematic review and meta-analysis. [PDF]

open access: yes, 2015
BACKGROUND: In the last two decades, India has witnessed a substantial decrease in infant mortality attributed to infectious disease and malnutrition. However, the mortality attributed to birth defects remains constant. Studies on the prevalence of birth
Allagh, Komal Preet   +7 more
core   +3 more sources

Resveratrol’s neural protective effects for the injured embryoid body and cerebral organoid

open access: yesBMC Pharmacology and Toxicology, 2022
Objective Resveratrol (RSV) is a polyphenol compound found in grapes, veratrum and other plants. It has been reported that RSV has anti-inflammatory, anti-oxidant, anti-cancer and other pharmacological effects.
Yanli Wang   +5 more
doaj   +1 more source

Establishment and validation of a carbohydrate metabolism-related gene signature for prognostic model and immune response in acute myeloid leukemia

open access: yesFrontiers in Immunology, 2022
IntroductionThe heterogeneity of treatment response in acute myeloid leukemia (AML) patients poses great challenges for risk scoring and treatment stratification. Carbohydrate metabolism plays a crucial role in response to therapy in AML.
You Yang   +8 more
doaj   +1 more source

Trends and predictors of women's risk perception about medications that may cause birth defects [PDF]

open access: yes, 2019
The purpose of this study was to evaluate the proportion of women who reported perception of medications as a risk for birth defects, whether perceptions have changed over time, and identify socioeconomic and medical factors that are independent ...
Samuelson, Mark
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

High Expression of VAV Gene Family Predicts Poor Prognosis of Acute Myeloid Leukemia

open access: yesTechnology in Cancer Research & Treatment, 2021
Objectives: VAV family genes ( VAV1, VAV2, and VAV3 ) are associated with prognosis in various cancers; however, they have not been evaluated in acute myeloid leukemia (AML). In this study, the prognostic value of VAV expression in AML was evaluated by a
Dan Mu BA   +3 more
doaj   +1 more source

Speckle noise reduction techniques for high-dynamic range imaging [PDF]

open access: yes, 2007
High-dynamic range imaging from space in the visible, aiming in particular at the detection of terrestrial exoplanets, necessitates not only the use of a coronagraph, but also of adaptive optics to correct optical defects in real time.
Belikov   +23 more
core   +3 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

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