Results 1 to 10 of about 187,040 (164)

Spatial Epidemiologic Analysis of Fetal Birth Defects in Guangxi, China [PDF]

International Journal of General Medicine
Zhenren Peng,1– 5,* Xiuning Huang,4,5,* Jie Wei,4,5,* Biyan Chen,4,5 Lifang Liang,4,5 Baoying Feng,4,5 Qiufen Wei,1– 5 Sheng He1– 5 1Birth Defects Research Laboratory, Guangxi Clinical Research Center for Birth Defects, Nanning ...
Peng Z, Huang X, Wei J, Chen B, Liang L, Feng B, Wei Q, He S   +7 more
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Epidemiology of birth defects based on a birth defects surveillance system in southwestern China and the associated risk factors

Frontiers in Pediatrics, 2023
BackgroundBirth defects (BDs) are associated with many potential risk factors, and its causes are complex.ObjectivesThis study aimed to explore the epidemiological characteristics of BDs in Guangxi of China and the associated risk factors of BDs ...
Zhenren Peng, Zhenren Peng, Zhenren Peng, Zhenren Peng, Jie Wei, Jie Wei, Jie Wei, Jie Wei, Biyan Chen, Biyan Chen, Biyan Chen, Biyan Chen, Xiuning Huang, Xiuning Huang, Xiuning Huang, Xiuning Huang, Pengshu Song, Pengshu Song, Pengshu Song, Pengshu Song, Lifang Liang, Lifang Liang, Lifang Liang, Lifang Liang, Jiajia He, Jiajia He, Jiajia He, Jiajia He, Baoying Feng, Baoying Feng, Baoying Feng, Baoying Feng, Ting Que, Ting Que, Ting Que, Ting Que, Jie Qin, Jie Qin, Jie Qin, Jie Qin, Yu'an Xie, Yu'an Xie, Yu'an Xie, Yu'an Xie, Xiaoxia Qiu, Xiaoxia Qiu, Xiaoxia Qiu, Xiaoxia Qiu, Hongwei Wei, Hongwei Wei, Hongwei Wei, Hongwei Wei, Sheng He, Sheng He, Sheng He, Sheng He   +55 more
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Identification of a novel compound heterozygous SMG9 variants in a Chinese family with heart and brain malformation syndrome using whole exome sequencing

BMC Medical Genomics, 2022
SMG9-deficiency syndrome, also known as heart and brain malformation syndrome, is a very rare congenital genetic disorder mainly characterized by brain, heart, and growth and developmental abnormalities.
Qi Yang, Zailong Qin, Qinle Zhang, Shang Yi, Sheng Yi, Jingsi Luo   +5 more
doaj   +1 more source

Novel compound heterozygous variants in the RPL3L gene causing dilated cardiomyopathy type-2D: a case report and literature review

BMC Medical Genomics, 2023
Background Dilated cardiomyopathy type-2D (CMD2D) is a rare heart disease causing a severe cardiomyopathy with neonatal onset and rapid progression to cardiac decompensation and death in untreated patients.
Qi Yang, Qiang Zhang, Zailong Qin, Shujie Zhang, Sheng Yi, Shang Yi, Qinle Zhang, Jingsi Luo   +7 more
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Exploring the mechanism of physcion-1-O-β-D-monoglucoside against acute lymphoblastic leukaemia based on network pharmacology and experimental validation

Heliyon, 2023
Objective: To explore the mechanism of PG against acute lymphoblastic leukaemia (ALL) by network pharmacology and experimental verification in vitro. Methods: First, the biological activity of PG against B-ALL was determined by CCK-8 and flow cytometry ...
Jing Liu, Yan Yang, Yan Zeng, Xiang Qin, Ling Guo, Wenjun Liu   +5 more
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Exploring the pharmacological mechanisms of Shuanghuanglian against T-cell acute lymphoblastic leukaemia through network pharmacology combined with molecular docking and experimental validation

Pharmaceutical Biology, 2023
Context Due to the poor prognosis of T-cell acute lymphoblastic leukaemia (T-ALL), there is an urgent need to identify safer and more cost-effective drugs.Objective This study evaluated the antitumour activity of Shuanghuanglian (SHL) on T-ALL cells and ...
You Yang, Yan Yang, Yunfu Shen, Jing Liu, Yan Zeng, Chengming Wei, Chunyan Liu, Yansha Pan, Qulian Guo, Fangfang Zhong, Ling Guo, Wenjun Liu   +11 more
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Case Report: Christianson Syndrome Caused by SLC9A6 Mutation: From Case to Genotype-Phenotype Analysis

Frontiers in Genetics, 2021
Christianson syndrome (CS) is an X-linked neurodevelopmental syndrome characterized by microcephaly, epilepsy, ataxia, and severe generalized developmental delay.
Yueyun Lan, Yueyun Lan, Sheng Yi, Sheng Yi, Mengting Li, Mengting Li, Jinqiu Wang, Qi Yang, Qi Yang, Shang Yi, Shang Yi, Fei Chen, Fei Chen, Limei Huang, Limei Huang, Yiyan Ruan, Yiping Shen, Yiping Shen, Yiping Shen, Jingsi Luo, Jingsi Luo, Zailong Qin, Zailong Qin   +22 more
doaj   +1 more source

Changes in prevalence and perinatal outcomes of congenital hydrocephalus among Chinese newborns: a retrospective analysis based on the hospital-based birth defects surveillance system

BMC Pregnancy and Childbirth, 2017
Background Little is known about the epidemiology of congenital hydrocephalus (CH) in China. This study aimed to depict recent changes in CH prevalence and perinatal outcomes of the affected newborns.
Ling Yi, Chaomin Wan, Changfei Deng, Xiaohong Li, Kui Deng, Yi Mu, Jun Zhu, Qi Li, Yanping Wang, Li Dai   +9 more
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Hinokiflavone induces apoptosis, cell cycle arrest and autophagy in chronic myeloid leukemia cells through MAPK/NF-κB signaling pathway

BMC Complementary Medicine and Therapies, 2022
Background Chronic myeloid leukemia (CML) is a myeloproliferative tumor originating from hematopoietic stem cells, and resistance to tyrosine kinase inhibitors (TKI) has become a major cause of treatment failure.
Xiang Qin, Xi Chen, Ling Guo, Jing Liu, You Yang, Yan Zeng, Cheng Li, Wenjun Liu, Wenzhe Ma   +8 more
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Diabetes mellitus and birth defects [PDF]

American Journal of Obstetrics and Gynecology, 2008
The purpose of this study was to examine associations between diabetes mellitus and 39 birth defects.This was a multicenter case-control study of mothers of infants who were born with (n = 13,030) and without (n = 4895) birth defects in the National Birth Defects Prevention Study (1997-2003).Pregestational diabetes mellitus (PGDM) was associated ...
Adolfo, Correa, Suzanne M, Gilboa, Lilah M, Besser, Lorenzo D, Botto, Cynthia A, Moore, Charlotte A, Hobbs, Mario A, Cleves, Tiffany J, Riehle-Colarusso, D Kim, Waller, E Albert, Reece   +9 more
openaire   +2 more sources