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Monoterpenoid Bisindole Alkaloids

2016
This chapter covers the literature on bisindole alkaloids consisting of monoterpenoid indoles, published up to June 2015. Bisindole alkaloids isolated from plants belonging to the families Apocynaceae and Loganiaceae, including Iboga-vobasine type, Aspidosperma-Aspidosperma type, eburnan-Aspidosperma type, Strychnos-Strychnos type, macroline-macroline ...
Mariko, Kitajima, Hiromitsu, Takayama
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ChemInform Abstract: Bisindole Alkaloids

ChemInform, 2009
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Toh‐Seok Kam, Yeun‐Mun Choo
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Anticancer activity of bisindole alkaloids derived from natural sources and synthetic bisindole hybrids

Archiv der Pharmazie, 2020
AbstractThe bisindole moiety, as a versatile pharmacophore, is one of the widespread heterocycles in naturally occurring and synthetic bioactive compounds. The bisindole alkaloids derived from natural sources possess structural and mechanistic diversity, and they were found to be generally more active than monoindole alkaloids against various cancer ...
Yue Zhang, Chunhong Hu
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Synthesis of Marine Sponge Bisindole Alkaloids Dihydrohamacanthins

Organic Letters, 2002
[structure: see text] A convergent synthesis of the marine sponge bisindole alkaloids dihydrohamacanthins is described. The synthesis centers on the construction of 3,5- and 3,6-linked pyrazinones and their reduction to the requisite piperazinones with sodium cyanoborohydride.
Fumiko Y, Miyake   +2 more
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The IBOGA alkaloids and their role as precursors of anti-neoplastic bisindole catharanthus alkaloids

ChemInform, 2002
AbstractFor Abstract see ChemInform Abstract in Full Text.
Richard J, Sundberg, Stanton Q, Smith
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Synthesis of a novel series of cytotoxic bisindole alkaloids

Bioorganic & Medicinal Chemistry Letters, 2001
Original cytotoxic bisindole alkaloids with a 1,2,3,4-tetrahydroquinoline bridge were synthesized by reductive amination with various anilines. The most cytotoxic compounds display a high and dose-dependent cell cycle effect with accumulation in the G1 phase.
M, Raoul   +6 more
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Alternative partial synthesis of bisindole alkaloids

Tetrahedron Letters, 1990
Abstract Indoline derivatives of the pericyclivine series are oxidized at position 6 with DDQ; the corresponding alcohols are coupled with nucleophilic indolines under acid conditions to yield dimers similar to undulatine.
G. Massiot   +3 more
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Leucophyllinines A and B, bisindole alkaloids from Leuconotis eugeniifolia

Journal of Natural Medicines, 2019
Two new bisindole alkaloids, leucophyllinines A (1) and B (2) consisting of eburnane and quebrachamine-type skeletons were isolated from the bark of Leuconotis eugeniifolia, and their structures were elucidated on the basis of spectroscopic data. Leucophyllinines A and B showed antiplasmodial activities against Plasmodium falciparum 3D7.
Tang, Yiming   +6 more
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Bisindole alkaloids.

The Alkaloids. Chemistry and biology, 2007
This chapter provides an overview on bisindole alkaloids. The indole–indole and tryptamine–tryptamine type, and related alkaloids are discussed. Tryptamine–tryptamine type with an additional monoterpene unit and related alkaloids are briefly discussed.
Kam, Toh Seok, Choo, Yeun Mun
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New Bisindole Alkaloids from Petchia Ceylanica

HETEROCYCLES, 1988
Two new bisindole alkaloids, ceylanine and ceylanicine, habe been isolated from Petchia ceylanica and their structures have been established on the basis of spectroscopic ...
_ Atta-ur-Rahman   +4 more
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