Results 151 to 160 of about 48,569 (170)

A partial synthesis of the Alstonia bisindole alkaloid villalstonine

Tetrahedron Letters, 1994
Abstract The partial synthesis of villalstonine 1 has been completed by coupling the macroline equivalent 2a with plant-derived (+)-pleiocarpamine 3 in 0.2N aq. hydrochloric acid in the presence of fluoride ion.
Yingzhi Bi, James M. Cook, Philip W. LeQuesne   +2 more
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Biomimetic synthesis and structure of the bisindole alkaloid alstonisidine

Journal of the Chemical Society, Chemical Communications, 1972
Alstonisidine, a bisindole alkaloid from Alstonia muelleriana, is assigned the revised structure (II) on the basis of its biomimetic synthesis from quebrachidine (III) and macroline (IV).
David E. Burke, James M. Cook, P. W. Le Quesne   +2 more
openaire   +1 more source

Vincazalidine A, a unique bisindole alkaloid from Catharanthus roseus

Journal of Natural Medicines
A new dimeric indole alkaloid, vincazalidine A consisting of an aspidosperma type and a modified iboga type with 1-azatricyclo ring system consisting of one azepane and two piperidine rings coupled with an oxazolidine ring was isolated from Catharanthus roseus, and the structure including absolute stereochemistry was elucidated on the basis of ...
Yusuke, Hirasawa, Ayaka, Kase, Akie, Okamoto, Keigo, Suzuki, Mizuki, Hiroki, Toshio, Kaneda, Nahoko, Uchiyama, Hiroshi, Morita   +7 more
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Partial synthesis of the antiamoebic bisindole alkaloid (−)-macrocarpamine

Tetrahedron Letters, 1996
Abstract The partial synthesis of the antiamoebic bisindole alkaloid (−)-macrocarpamine 1 has been completed by coupling (−)-anhydromacrosalhine-methine 2 with plant-derived (+)-pleiocarpamine 3 in anhydrous 0.2 N HCl in THF in 75% yield.
Tong Gan, James M. Cook
openaire   +1 more source

New Bisindole Alkaloids from Tabernaemontana corymbosa

Journal of Natural Products, 2002
Ten new bisindole alkaloids of the vobasinyl-ibogan type, viz., conodiparines A-F (1-6), conodutarines A and B (7, 8), and cononitarines A and B (9, 10), were obtained from the leaf extract of the Malayan species Tabernaemontana corymbosa. The structures were determined using NMR and MS analysis.
Toh-Seok, Kam, Kooi-Mow, Sim, Huey-Shen, Pang   +2 more
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Aspidospermatan–aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis

Phytochemistry, 2010
Leucofoline and leuconoline, representing the first members of the aspidospermatan-aspidospermatan and eburnane-sarpagine subclasses of the bisindole alkaloids, respectively, were isolated from the Malayan Leuconotis griffithii. The structures of these bisindole alkaloids were established using NMR and MS analysis, and in the case of leuconoline ...
Gan, Chew Yan, Low, Yun Yee, Robinson, W.T., Komiyama, K., Kam, Toh Seok   +4 more
openaire   +3 more sources

Syntheses of the Bisindole Alkaloids of the Genera Borreria and Flindersia

2014
Abstract The flinderoles and their structural isomers, the borreverines, have intriguing chemical structures and promising biological activity. These indole alkaloids each contain multiple stereocenters that challenge synthetic chemists to develop new reaction methods. Proven antimalarial activity further established the synthesis of these targets as
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The bisindole alkaloid catharine

Acta Crystallographica Section B Structural Crystallography and Crystal Chemistry, 1976
J. Guilhem, A. Ducruix, C. Riche, C. Pascard   +3 more
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Novel Bisindole Derivatives Of Catharanthus Alkaloids With Potential Cytotoxic Properties

2003
Pantropical plant Catharanthus roseus (L) G. Don is known as a source of valuable bisindole alkaloids: vinblastine (VBL) and vincristine (VCR), oncolytics widely used as sulfates in therapy of malignant diseases. They are biosynthesized in the plant from monoindolic vindoline and catharanthine, both derived from L-tryptophan and loganine units.
Joanna, Ruszkowska, Robert, Chrobak, Jerzy T, Wróbel, Zbigniew, Czarnocki   +3 more
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Bisindole Alkaloids of Pandaca caducifolia

Journal of Natural Products, 1982
Monique Zeches, Gabor Lukacs, Georges Massiot Louisette Le Men-Olivier, Maurice-Marie Debray   +3 more
openaire   +1 more source