Results 121 to 130 of about 70,439 (171)
Aspidospermatan–aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis
Phytochemistry, 2010 Leucofoline and leuconoline, representing the first members of the aspidospermatan-aspidospermatan and eburnane-sarpagine subclasses of the bisindole alkaloids, respectively, were isolated from the Malayan Leuconotis griffithii. The structures of these bisindole alkaloids were established using NMR and MS analysis, and in the case of leuconoline ...
Gan, Chew Yan +4 more
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Archiv Der Pharmazie, 2020
AbstractThe bisindole moiety, as a versatile pharmacophore, is one of the widespread heterocycles in naturally occurring and synthetic bioactive compounds. The bisindole alkaloids derived from natural sources possess structural and mechanistic diversity, and they were found to be generally more active than monoindole alkaloids against various cancer ...
Yue Zhang, Chunhong Hu
exaly +3 more sources
AbstractThe bisindole moiety, as a versatile pharmacophore, is one of the widespread heterocycles in naturally occurring and synthetic bioactive compounds. The bisindole alkaloids derived from natural sources possess structural and mechanistic diversity, and they were found to be generally more active than monoindole alkaloids against various cancer ...
Yue Zhang, Chunhong Hu
exaly +3 more sources
Monoterpenoid Bisindole Alkaloids
The Alkaloids Chemistry and Biology, 2016This chapter covers the literature on bisindole alkaloids consisting of monoterpenoid indoles, published up to June 2015. Bisindole alkaloids isolated from plants belonging to the families Apocynaceae and Loganiaceae, including Iboga-vobasine type, Aspidosperma-Aspidosperma type, eburnan-Aspidosperma type, Strychnos-Strychnos type, macroline-macroline ...
Mariko Kitajima
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, 2006 Publisher Summary This chapter provides an overview on bisindole alkaloids. The indole–indole and tryptamine–tryptamine type, and related alkaloids are discussed. Tryptamine–tryptamine type with an additional monoterpene unit and related alkaloids are briefly discussed.
Toh-Seok Kam +3 more
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Biologically active indole and bisindole alkaloids from Tabernaemontana divaricata
Organic & Biomolecular Chemistry, 2003 AbstractFor Abstract see ChemInform Abstract in Full Text.
Kam, Toh-Seok +2 more
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Bisindole alkaloids from Tabernaemontana corymbosa
Phytochemistry, 2018Continued study in bioactive monoterpenoid alkaloids led to the isolation of nine undescribed alkaloids, taberyunines A-I, together with 32 known ones from the aerial parts of Tabernaemontana corymbosa Roxb. ex Wall (Apocynaceae). Among the undescribed alkaloids, taberyunines A-G and H-I were assigned to Aspidosperma-Aspidosperma and Vobasinyl-Ibogan ...
Bing-Jie, Zhang +6 more
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ChemInform Abstract: Bisindole Alkaloids
ChemInform, 2009AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Toh‐Seok Kam, Yeun‐Mun Choo
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Synthesis of Marine Sponge Bisindole Alkaloids Dihydrohamacanthins
Organic Letters, 2002[structure: see text] A convergent synthesis of the marine sponge bisindole alkaloids dihydrohamacanthins is described. The synthesis centers on the construction of 3,5- and 3,6-linked pyrazinones and their reduction to the requisite piperazinones with sodium cyanoborohydride.
Fumiko Y, Miyake +2 more
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The IBOGA alkaloids and their role as precursors of anti-neoplastic bisindole catharanthus alkaloids
ChemInform, 2002AbstractFor Abstract see ChemInform Abstract in Full Text.
Richard J, Sundberg, Stanton Q, Smith
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Synthesis of a novel series of cytotoxic bisindole alkaloids
Bioorganic & Medicinal Chemistry Letters, 2001Original cytotoxic bisindole alkaloids with a 1,2,3,4-tetrahydroquinoline bridge were synthesized by reductive amination with various anilines. The most cytotoxic compounds display a high and dose-dependent cell cycle effect with accumulation in the G1 phase.
M, Raoul +6 more
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