Bioequivalence study of two formulations of bisoprolol fumarate film-coated tablets in healthy subjects [PDF]
Raymond R Tjandrawinata,1 Effi Setiawati,2 Danang Agung Yunaidi,2 Iwan Dwi Santoso,2 Arini Setiawati,3 Liana W Susanto11Dexa Laboratories of Biomolecular Sciences (DLBS), Cikarang, Indonesia; 2Bioavailability and Bioequivalence Laboratory, Equilab ...
Tjandrawinata RR +5 more
doaj +8 more sources
A pilot study of re-purposing drugs to treat koalas with chlamydia [PDF]
The koala (Phascolarctos cinereus) is an endangered species in parts of Australia, in part due to chlamydial infections. Treatment is difficult due to the hepatic metabolism of the koala, and the critical reliance on a gut microbiota for survival.
Charlotte Fleming +7 more
doaj +3 more sources
Application of Hydrophilic Polymers to the Preparation of Prolonged-Release Minitablets with Bromhexine Hydrochloride and Bisoprolol Fumarate [PDF]
Minitablets have been extensively studied in recent years as a convenient pediatric form because they allow successful administration even in very young children.
Agata Grzejdziak +5 more
doaj +2 more sources
Three spectrophotometric quantitative analysis of bisoprolol fumarate and telmisartan in fixed-dose combination utilizing ratio spectra manipulation methods [PDF]
Hypertension is a chronic condition with multiple drug regimens. Limiting these medicines is critical to patient compliance. Therefore, bisoprolol and telmisartan were recently developed in a fixed-dose combination to control blood pressure.
Osama I. Abdel Sattar +3 more
doaj +2 more sources
A spectrofluorimetric method was developed to determine residues of two β-blockers, atenolol (AT) and bisoprolol fumarate (BF), in Senegal's natural waters.
Coumba Gueye +8 more
doaj +2 more sources
An Insight on Analytical Profile on Bisoprolol Fumarate – A Selective Beta-1 Adrenoreceptor Blocker [PDF]
BF is Beta-adreno receptor antagonist and used as an AntiHypertensive Drug. BF gives the blocking action on β1-adrenergic receptors in the heart and vascular smooth muscle. The present review compiles the various approaches implemented for quantification of BF in bulk drug, pharmaceutical matrix and biological fluid. This review represents more than 50
Ajinkya G. Dhandar +5 more
openaire +3 more sources
Background: The study aimed to prepare and evaluate the transdermal film of bisoprolol fumarate (BF) for chronic management of hypertension as an alternative to conventional oral dosage form.
H. N. Shivakumar +4 more
doaj +2 more sources
Dual-platform integration of HPTLC and firefly algorithm-optimized chemometrics with hammersley sequence sampling for simultaneous quantification of bisoprolol, amlodipine, and mutagenic impurity 4-hydroxybenzaldehyde [PDF]
The simultaneous quantification of active pharmaceutical ingredients alongside their mutagenic impurities represents a critical challenge in pharmaceutical quality control.
Lateefa A. Al-Khateeb +6 more
doaj +2 more sources
Substantiation of conditions for determination of related substances in bisoprolol fumarate by HPLC
The article summarizes the results of information analysis of bisoprolol fumarate synthesis methods which differ in the number of stages and in raw materials used, and are associated with the major identified impurities A, E and G, according to the ...
O. A. Baturina +7 more
doaj +1 more source
Development and validation of a fast and simple HPLC method for the simultaneous determination of bisoprolol and enalapril in dosage form [PDF]
Aim. We aimed to develop and validate fast, simple, accurate, robust and rugged chromatographic method for simultaneous determination of bisoprolol fumarate and enalaril maleate in solid pharmaceutical dosage form, with using chaotropic strong chaotropic
Marjan Piponski +2 more
doaj +3 more sources

