Results 11 to 20 of about 744 (160)

Substantiation of conditions for determination of related substances in bisoprolol fumarate by HPLC

Регуляторные исследования и экспертиза лекарственных средств, 2018
The article summarizes the results of information analysis of bisoprolol fumarate synthesis methods which differ in the number of stages and in raw materials used, and are associated with the major identified impurities A, E and G, according to the ...
O. A. Baturina, E. V. Chaykovskaya, E. P. Gernikova, T. N. Bokovikova, L. A. Stronova, Yu. R. Biglova, S. A. Manaeva, E. S. Tolmacheva   +7 more
doaj   +1 more source

Antihypertensive Efficacy, Safety, and Adherence After Switching From a Free Combination of Bisoprolol/Metoprolol and Amlodipine to Bisoprolol/Amlodipine FDC Tablets (5/5 mg) in Chinese Patients With Hypertension. [PDF]

J Clin Hypertens (Greenwich)
ABSTRACT Hypertension is a leading chronic disease globally, with rising prevalence in China. A considerable number of hypertension patients struggle to achieve target blood pressure levels with monotherapy alone. The bisoprolol/amlodipine FDC shows promise for blood pressure control and adherence, whereas clinical evidence for Chinese patients is ...
Wang N, Zhou X, Han J, Jiang J, Ma L, Liu G, Liu R, Kong Y, Tang Y, Jiang W, Wei Y, Cheng W.   +11 more
europepmc   +2 more sources

Intravenous Tolvaptan Sodium Phosphate Can Fail to Improve Fluid Overload Due to Heart Failure in Patients With Chronic Kidney Disease: A Case Report. [PDF]

Pharmacol Res Perspect
ABSTRACT Tolvaptan is widely used as an adjunct oral diuretic to loop and thiazide diuretics for the management of fluid overload in patients with congestive heart failure. Recently, tolvaptan sodium phosphate (TSP), a water‐soluble prodrug of tolvaptan, was developed for intravenous administration and has demonstrated efficacy and safety in clinical ...
Uno T, Nakakura I, Ikeda A, Hosoda A, Mukai Y, Yamanishi K, Ohara N, Imanishi K, Une Y, Yokoyama S, Hosomi K.   +10 more
europepmc   +2 more sources

Nephrotic-Nephritic Syndrome Following Unilateral Nephrectomy in Wilms Tumour in a Child. [PDF]

Case Rep Nephrol
Background Wilms tumour (WT) represents the most frequent kidney malignant tumour in the paediatric population and is occasionally linked to specific congenital syndromes. Treatment typically includes multimodal therapy consisting of chemotherapy, surgery and/or radiotherapy (RT), with a success rate of approximately 90%.
Jaber RZ.
europepmc   +2 more sources

Amiodarone-Induced Pneumonia Without Foamy Macrophages in the BALF: A Diagnostic Challenge Unveiled by Cryobiopsy. [PDF]

Respirol Case Rep
Amiodarone‐induced pneumonia can occur even in the absence of foamy macrophages in bronchoalveolar lavage fluid, potentially leading to diagnostic uncertainty. In this case, transbronchial lung cryobiopsy revealed characteristic histopathological features, including vacuolization of type II alveolar epithelial cells and lymphoid hyperplasia, enabling a
Tsunoda T, Tsuchiya K, Oyama Y, Yazawa S, Miyamoto R, Ito T, Akashi T, Enomoto N, Fujisawa T, Ikeda M, Suda T.   +10 more
europepmc   +2 more sources

Bisoprolol transdermal patch improves orthostatic hypotension in patients with chronic heart failure and hypertension

Clinical and Experimental Hypertension, 2020
β blockers (BBs) play an important role in heart failure (HF) treatment. However, orthostatic hypotension (OH) is sometimes caused by BBs. The bisoprolol transdermal patch works more slowly and is long acting compared with the bisoprolol fumarate tablet.
Shunsuke Kiuchi, Shinji Hisatake, Takayuki Kabuki, Takashi Oka, Shintaro Dobashi, Takahiro Fujii, Takahide Sano, Takanori Ikeda   +7 more
doaj   +1 more source

Forced degradation studies and structural characterization of related substances of bisoprolol fumarate in finished drug product using LC-UV-MS/MS [PDF]

Journal of the Serbian Chemical Society, 2022
Methods for determination of bisoprolol and related substances mostly use UV detection and a phosphate buffer and are not suitable for MS detection.
Lazarevska-Todevska Elena, Piponski Marjan, Stefova Marina   +2 more
doaj   +1 more source

Spectrofluorimetric determination of beta-blockers atenolol and bisoprolol fumarate residues in Senegal natural waters

Macedonian Journal of Chemistry and Chemical Engineering, 2023
A spectrofluorimetric method was developed to determine residues of two β-blockers, atenolol (AT) and bisoprolol fumarate (BF), in Senegal's natural waters.
Coumba Gueye, Pape Abdoulaye Diaw, Moussa Mbaye, Olivier Maurice Aly Mbaye, Lamine Cissé, Diabou Gaye Seye, Jean-Jacques Aaron, Nihal Oturan, Mehmet Oturan   +8 more
doaj   +1 more source

Investigation of the Effects of Some Cardiovascular Drugs on Angiogenesis by Transgenic Zebrafish

Mediators of Inflammation, 2023
Introduction. Angiogenesis contributes to the pathophysiology of cardiovascular disease (CVD). Some cardiovascular drugs used in the treatment of CVD have an effect on the process of angiogenesis. Methods.
Hui Lv, Bo Liu, Yongwen Qin
doaj   +1 more source

Resting heart rate control and prognosis in coronary artery disease patients with hypertension previously treated with bisoprolol: a sub-group analysis of the BISO-CAD study

Chinese Medical Journal, 2020
. Background. Resting heart rate (RHR) is considered as a strong predictor of total mortality and hospitalization due to heart failure in hypertension patients. Bisoprolol fumarate, a second-generation beta-adrenoreceptor blockers (β-blocker) is commonly
Yun-Dai Chen, Xin-Chun Yang, Vinh Nguyen Pham, Shi-An Huang, Guo-Sheng Fu, Xiao-Ping Chen, Binh Quang Truong, Yu Yang, Shao-Wen Liu, Tian-Rong Ma, Dong-Soo Kim, Tae-hoon Kim, Ning-Ning Wang   +12 more
doaj   +1 more source