Results 21 to 30 of about 744 (160)

Study of forced degradation of amlodipine besylate and bisoprolol fumarate by application of hydrophilic interaction liquid chromatography [PDF]

Arhiv za farmaciju, 2014
Currently, in pharmaceutical analysis, great importance is given to forced degradation studies, which can greatly help to predict the shelf life of the drug, but also for identification of possible degradation products. These studies enable investigation
Kasagić-Vujanović Irena, Jančić-Stojanović Biljana, Ivanović Darko   +2 more
doaj   +1 more source

Resistance to thyroid hormone accompanied by atrial fibrillation

Endocrinology, Diabetes & Metabolism Case Reports, 2018
Resistance to thyroid hormone (RTH), which is primarily caused by mutations in the thyroid hormone (TH) receptor beta (THRB) gene, is dominantly inherited syndrome of variable tissue hyposensitivity to TH.
Haruhiro Sato, Yuichiro Tomita
doaj   +1 more source

Comparison of the Transdermal Bisoprolol Patch with Oral Bisoprolol Fumarate Administration as a Therapeutic Agent for Idiopathic Frequent Premature Ventricular Contractions

International Heart Journal, 2020
The transdermal bisoprolol patch (TB) was designed to maintain a sustained concentration of bisoprolol in plasma by a higher trough concentration than oral bisoporolol (OB). We compared the efficacy between TB and OB in patients with idiopathic premature ventricular contractions (PVCs) while considering their duration of action.A total of 78 patients ...
Shinohara, Masaya, Wada, Ryou, Yao, Shintaro, Yano, Kensuke, Akitsu, Katsuya, Koike, Hideki, Kinoshita, Toshio, Yuzawa, Hitomi, Suzuki, Takeya, Fujino, Tadashi, Ikeda, Takanori   +10 more
openaire   +4 more sources

Unilateral adrenalectomy for a drug-resistant bilateral primary aldosteronism with heart failure: pathophysiology and surgical indication

BMC Endocrine Disorders, 2023
Background Patients with bilateral primary aldosteronism (PA) generally are treated with antihypertensive drugs, but optimal treatment for patients with complications due to refractory hypertension has not been established.
Seiji Hoshi, Akifumi Onagi, Ryo Tanji, Ruriko Honda-Takinami, Kanako Matsuoka, Junya Hata, Yuichi Sato, Hidenori Akaihata, Masao Kataoka, Soichiro Ogawa, Yoshiyuki Kojima   +10 more
doaj   +1 more source

The Maillard reaction of bisoprolol fumarate with various reducing carbohydrates

European Journal of Pharmaceutical Sciences, 2014
HPLC analysis of drug products containing bisoprolol fumarate and lactose revealed the presence of N-formylbisoprolol, which is a final product of the Maillard reaction. Formulations containing secondary amines and reducing carbohydrates are prone to the condensation of amine and carbonyl functional groups and formation of glycosylamines in ...
Mateusz, Szalka, Jacek, Lubczak, Dorota, Naróg, Marek, Laskowski, Krzysztof, Kaczmarski   +4 more
openaire   +2 more sources

Comparative Analysis of Compendial Requirements for the Quality of Bisoprolol Products

Регуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. Beta-blockers are one of the major groups of medicines used to treat cardiovascular diseases. Bisoprolol fumarate is of particular interest as it shows high selectivity towards beta-1 receptors.
O. A. Matveeva, E. L. Kovaleva, A. P. Karpushina, V. V. Akopova   +3 more
doaj   +1 more source

Impurity profiling of bisoprolol fumarate by liquid chromatography-high-resolution mass spectrometry: A combination of targeted and untargeted approaches using a synthesis reaction matrix and general unknown comparative screening

Journal of Chromatography Open, 2021
Several examples of the emergence of unexpected impurities in medicinal products in the past, e.g. the 2018 valsartan scandal, disclosed the need for sophisticated approaches in impurity profiling.
Jonas Wohlfart, Elisabeth Jäckel, Oliver Scherf-Clavel, Dirk Jung, Martina Kinzig, Fritz Sörgel, Ulrike Holzgrabe   +6 more
doaj   +1 more source

Case report: Impact of hyperthyroidism on psychotic symptoms in schizophrenia comorbid with Graves’ disease

Frontiers in Psychiatry, 2023
IntroductionAuditory hallucinations are the most common type of hallucinations observed in schizophrenia; however, visual hallucinations are not uncommon. In Graves’ disease, depression, hypomania, and psychosis can occur.
Yukiyoshi Sumi, Sanae Kawahara, Kumiko Fujii, Mayu Yamaji, Kou Nakajima, Tsubasa Nakamura, Osamu Horikawa, Yukihiro Fujita, Yuji Ozeki   +8 more
doaj   +1 more source

Effects of fixed orthodontic appliance with antihypertensive drugs on the body weight of experimental rats

Journal of Baghdad College of Dentistry, 2023
Background: This study aims to investigate the effect of fixed orthodontic appliances and/or antihypertensive drugs on the weight of experimental rats.
Hadeel A Mahdi , Hayder F Saloom , Muhanad A Kashmola   +2 more
doaj   +1 more source

Development and validation of an analytical method for the determination of related substances in bisoprolol fumarate in dosage forms by HPLC-UV-DAD

Macedonian Journal of Chemistry and Chemical Engineering, 2021
The aim of this work was the development of an efficient analytical method for the determination of bisoprolol and related substances in the finished drug product using HPLC/DAD.
Elena Lazarevska Todevska, Marjan Piponski, Marina Stefova   +2 more
doaj   +1 more source