Recombinant approaches to IgG-like bispecific antibodies [PDF]
Jonathan S. Marvin, Zhenping Zhu
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ABSTRACT Objectives The objective of this systematic literature review (SLR) combined with expert clinical review was to identify and rank prognostic factors and effect measure modifiers (EMMs) systematically and comprehensively in patients with relapsed or refractory (R/R) diffuse large B‐cell lymphoma (DLBCL) who initiate treatment after ≥ 2 prior ...
Bastian von Tresckow+19 more
wiley +1 more source
Efficacy and Safety of Bendamustine‐Rituximab for Nodular Lymphocyte Predominant Hodgkin Lymphoma
ABSTRACT Introduction Bendamustine‐rituximab (BR) has demonstrated efficacy and tolerability in the treatment of various indolent B‐cell lymphomas, but there is limited data regarding its outcomes in nodular lymphocyte predominant B‐cell (Hodgkin) lymphoma (NLPBL).
Alexander Robin+6 more
wiley +1 more source
Successful targeting of multidrug-resistant tumors with bispecific antibodies. [PDF]
Briante R+12 more
europepmc +1 more source
Selective Targeting and Potent Control of Tumor Growth Using an EphA2/CD3-Bispecific Single-Chain Antibody Construct [PDF]
Scott A. Hammond+10 more
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Extracellular vesicles in multiple myeloma: pathogenesis and therapeutic application
Multiple myeloma is characterised by the clonal proliferation of plasma cells in the bone marrow. Extracellular vesicles (EVs) are a key component of cell‐to‐cell communication within the bone marrow microenvironment, promoting tumour growth, bone remodelling, immune modulation, angiogenesis and therapeutic resistance.
Chloe Wylie+3 more
wiley +1 more source
Bispecific antibodies combined with chemotherapy in solid tumor treatment, the path forward? [PDF]
Yan Y+6 more
europepmc +1 more source
Improved Pharmacokinetics of Recombinant Bispecific Antibody Molecules by Fusion to Human Serum Albumin [PDF]
Dafne Müller+5 more
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Haemophilia Prophylaxis in the Age of Innovation: Exploring Opportunities for Personalized Treatment
ABSTRACT Introduction Recent advancements in haemophilia treatment have introduced a range of innovative therapies, including activated FVIII mimetics, ultra‐extended half‐life recombinant FVIII, rebalancing agents and gene therapy. These developments have transformed treatment options and expanded prophylaxis strategies.
Yesim Dargaud+5 more
wiley +1 more source