Results 221 to 230 of about 1,468,461 (396)

130. Targeting of Adenovirus Vectors to Mesothelin Via a Bispecific Antibody Reveals Enhanced Gene Transfer to Human Pancreatic Cancer Cells [PDF]

, 2004
MA van Geer, No Value Pastan, VW van Beusechem, Hidde J. Haisma, PJ Bosma, DJ Gouma, J. Wesseling   +6 more
openalex   +1 more source

Tumour progression shows decrease in PD‐L1 expression in matched metastases/primary uveal melanomas

Acta Ophthalmologica, EarlyView.
Abstract Purpose Immune checkpoint inhibitors (ICI) have revolutionised the treatment of several malignancies. However, the results of ICI therapy remain unsatisfactory in metastatic uveal melanoma (UM). We analysed the expression of PD1, PD‐L1, T‐cell and macrophage markers in a set of matched primary and metastatic UM in an attempt to better ...
Maria Chiara Gelmi, Gulçin Gezgin, Ellen Kapiteijn, T. H. Khanh Vu, Martine J. Jager, Robert M. Verdijk   +5 more
wiley   +1 more source

Recombinant bispecific antibodies for cancer therapy [PDF]

, 2005
Roland E. Kontermann
openalex   +1 more source

Copanlisib in combination with rituximab and bendamustine for transplant‐ineligible relapsed/refractory diffuse large B‐cell lymphoma patients: Results from the phase II multicentre FIL Copa‐BR trial from Fondazione Italiana Linfomi (FIL)

British Journal of Haematology, EarlyView.
A phase II, single‐arm, multicentre trial was conducted by Fondazione Italiana Linfomi (FIL) to investigate the combination of copanlisib plus rituximab and bendamustine (copa‐BR) in transplant‐ and chimeric antigen receptor (CAR)‐T‐ineligible relapsed/refractory (R/R) diffuse large B‐cell lymphoma (DLBCL). Thirty‐seven patients were enrolled.
Mattia Novo, Pio Manlio Mirko Frascione, Alessia Castellino, Luigi Marcheselli, Samantha Deianira Dattoli, Margherita Vannucchi, Delia Rota‐Scalabrini, Alessandra Tucci, Guido Gini, Giuseppe Tarantini, Donato Mannina, Annalisa Arcari, Arcangelo Liso, Elisabetta Scarpa, Dario Marino, Michele Spina, Ausilia Gorgone, Nicola Di Renzo, Salvatrice Mancuso, Luigi Petrucci, Agostino Tafuri, Barbara Botto, Francesca Bonello, Elisa Santambrogio, Umberto Vitolo   +24 more
wiley   +1 more source

Recombinant approaches to IgG-like bispecific antibodies [PDF]

, 2005
Jonathan S. Marvin, Zhenping Zhu
openalex   +1 more source

The anti‐CD47 antibody magrolimab with obinutuzumab and venetoclax in relapsed or refractory indolent B‐cell lymphomas

British Journal of Haematology, EarlyView.
Follicular lymphoma (FL), marginal zone lymphoma (MZL), chronic lymphocytic leukaemia (CLL) and mantle cell lymphoma (MCL) are characterized by a continuous incidence of relapse and increasing resistance to therapy. Novel immunotherapy approaches are needed.
Rahul Lakhotia, Christopher Melani, Stefania Pittaluga, Max J. Gordon, James D. Phelan, Jagan R. Muppidi, Atekelt Tadese, Sarah Evans, Elaine S. Jaffe, Louis M. Staudt, Wyndham H. Wilson, Mark Roschewski   +11 more
wiley   +1 more source

Bispecific antibodies: advancing precision oncology.

Trends in Cancer
Mercedes Herrera, Giulia Pretelli, Jayesh Desai, E. Garralda, L. Siu, Thiago M. Steiner, Lewis Au   +6 more
semanticscholar   +1 more source

We are on the right track for mantle cell lymphoma

British Journal of Haematology, EarlyView.
Commentary on: Alzahrani et al. Therapeutic advances and gradual improvement in overall survival in mantle cell lymphoma over 4 decades. Br J Haematol 2025 (Online ahead of print). doi: 10.1111/bjh.20239.
Alessia Moioli, Carlo Visco
wiley   +1 more source

Bispecific Antibodies in Hematologic Malignancies: Attacking the Frontline. [PDF]

BioDrugs
Shastri T, Trabolsi A, Arumov A, Schatz JH.   +3 more
europepmc   +1 more source

Consistent ex vivo cell proliferation during manufacturing predicts favourable outcomes post‐CAR‐T‐cell therapy

British Journal of Haematology, EarlyView.
Efficacy of chimeric antigen receptor (CAR) T‐cell therapy depends not only on tumour traits but also on the potency of CAR‐T cells. In clinical practice, the degrees of cell proliferation during CAR‐T‐cell manufacturing vary significantly among individual cases.
Tomoyasu Jo, Yasuyuki Arai, Tomoshige Shimizu, Toshio Kitawaki, Takashi Sakamoto, Chisaki Mizumoto, Junya Kanda, Momoko Nishikori, Kohei Yamashita, Miki Nagao, Akifumi Takaori‐Kondo   +10 more
wiley   +1 more source