Results 91 to 100 of about 9,802 (262)

Nitrate Prevents Sjögren's Disease by Modulating T Helper Cells via NF‐κB Pathway Suppression

open access: yesOral Diseases, EarlyView.
ABSTRACT Objective Sjögren's disease (SjD) is a chronic autoimmune disease characterized by abnormal T helper (Th) cell distribution in the salivary glands (SGs). Although nitrate can regulate immune responses and preserve SGs function, its preventive effects on SjD remain unexplored.
Conglin Du   +8 more
wiley   +1 more source

Radiographic Analysis of MRONJ in Osteoporotic and Oncologic Patients on Bisphosphonates or Denosumab

open access: yesOral Diseases, EarlyView.
ABSTRACT Introduction Medication‐Related Osteonecrosis of the Jaw (MRONJ) is a severe adverse effect of antiresorptive and antiangiogenic treatment, primarily in osteoporotic and oncologic patients. The disease is characterized by persistent jawbone necrosis that results in significant impairment of the quality of life of involved patients.
Omar Ghanaiem   +2 more
wiley   +1 more source

Dental extraction following zoledronate, induces osteonecrosis in rat´s jaw [PDF]

open access: yes, 2017
Bisphosphonate-Related Osteonecrosis of the Jaw (BRONJ) is clinically characterized by the presence of exposed bone in the oral cavity that persists for more than eight weeks.
Gaitán Cepeda, Luis Alberto   +2 more
core   +1 more source

Emerging locally delivered antimicrobial and immunomodulatory approaches for the prevention/treatment of peri‐implant diseases

open access: yesPeriodontology 2000, EarlyView.
Abstract Peri‐implant diseases are dysbiosis‐mediated inflammatory disorders that occur in susceptible hosts. Antimicrobials and immunomodulatory agents therefore might be pertinent as adjunctive measures in the treatment of such disorders. The aim of this narrative review was to examine the existing evidence and assess the effectiveness of emerging ...
Alberto Monje   +3 more
wiley   +1 more source

Role of ozone therapy in the treatment of osteonecrosis of the jaws in multiple myeloma patients

open access: yesHaematologica, 2007
Current treatments for bisphosphonate-associated osteonecrosis of the jaw (ONJ) in multiple myeloma patients have limited efficacy. The biological effects of ozone indicate it may be therapeutic for ONJ.
Maria Teresa Petrucci   +4 more
doaj   +1 more source

Association between bisphosphonates and jaw osteonecrosis: a study in Wistar rats [PDF]

open access: yes, 2011
BACKGROUND: This work aimed at determining whether bisphosphonate therapy produces a sufficient condition for jaw osteonecrosis after tooth extraction. METHODS: Rats were allocated into 3 groups: (1) 11 rats treated with alendronate, (2) 10 rats treated ...
Azambuja, Alan Arrieira   +4 more
core   +1 more source

The Effects of Bone‐Remodeling Therapy on Survival, Pain, and Skeletal Related Events in the Setting of Renal Cell Carcinoma With Bone Metastases: A Multicenter Investigation From a Large Global Health Research Network (TriNetX)

open access: yesCancer Medicine, Volume 15, Issue 1, January 2026.
In this retrospective population study containing 139,859 patients, subjects receiving RANK‐ligand inhibitors had improved survival and decreased rates of skeletal‐related events relative to the overall cohort of patients with metastatic bone lesions.
Brian H. Im   +9 more
wiley   +1 more source

Bisphosphonate-related osteonecrosis of the jaw in patients with multiple myeloma [PDF]

open access: yes, 2008
Purpose: To review the main clinical-radiographic, therapeutic, and preventive aspects of osteonecrosis related to intravenous bisphosphonate therapy in patients with multiple myeloma.
Cabezas Macián, Antonio   +4 more
core  

Oral bisphosphonate-associated osteonecrosis of maxillary bone: a review of 18 cases [PDF]

open access: yes, 2014
Biphosphonate-associated maxillary bone osteonecrosis (BPMO) is a complication related to nitrogen-containing biphosphonate therapy. This adverse effect occasionally appears in patients who are administered biphosphonates through intravenous infusion for
Escovich, Livia   +3 more
core   +1 more source

Adjuvant pharmacological strategies for the musculoskeletal system during long‐term space missions

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 1, Page 11-23, January 2026.
Abstract Despite 2 h of daily exercise training, muscle wasting and bone loss are still present after 6‐month missions to the international space station. Some crew members lose bone much faster than others. In preparation for missions to the Moon and Mars, space agencies are therefore reviewing their countermeasure portfolios.
Friederike Thomasius   +2 more
wiley   +1 more source

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