Descreveremos a ocorrência de osteonecrose da mandíbula associada ao uso de pamidronato (Aredia ) em uma paciente portadora de mieloma múltiplo. Apesar de não ser possível provar definitivamente a associação entre a terapia com bisfosfonatos e a ...
Andréia C. Melo +4 more
doaj +1 more source
Surgical resection for advanced bisphosphonate-related osteonecrosis of the jaw associated with fibrous dysplasia: a case report [PDF]
Yurika Murase +6 more
openalex +1 more source
The epidemiology of osteonecrosis: findings from the GPRD and THIN databases in the UK [PDF]
Summary We conducted a case–control study to examine osteonecrosis (ON) incidence, patient characteristics, and selected potential risk factors using two health record databases in the UK.
C. Cooper +23 more
core +2 more sources
Background/Objectives: Medication-related osteonecrosis of the jaw (MRONJ) is a challenging condition often associated with bisphosphonate use, leading to impaired bone healing and difficult clinical management.
Leonardo Alan Delanora +8 more
doaj +1 more source
Correction to: A multicenter retrospective study of the risk factors associated with medication-related osteonecrosis of the jaw after tooth extraction in patients receiving oral bisphosphonate therapy: can primary wound closure and a drug holiday really prevent MRONJ? [PDF]
Takumi Hasegawa +17 more
openalex +1 more source
Intravenous bisphosphonate-related osteonecrosis of the jaws: influence of coadjuvant antineoplastic treatment and study of buccodental condition [PDF]
Objectives: To determine whether coadjuvant antineoplastic treatment can influence the number and size of bone exposures among patients with intravenous bisphosphonaterelated osteonecrosis of the jaws (iBRONJ), and to analyze the buccodental condition ...
Bagán Sebastián, José Vicente +2 more
core +1 more source
The dynamin inhibitor, dynasore, prevents zoledronate-induced viability loss in human gingival fibroblasts by partially blocking zoledronate uptake and inhibiting endosomal acidification [PDF]
Objective For treatment of medication-related osteonecrosis of the jaw, one proposed approach is the use of a topical agent to block entry of these medications in oral soft tissues.
Jacob KIRBY +14 more
doaj +1 more source
Osteopathology induced by bisphosphonates and dental implants: clinical observations [PDF]
Objectives: Although there are many reports about risk factors for the development of BP-associated osteonecrosis of the jaws, the role of dental implants as a local risk factor is still discussed, especially in patients with oral BP treatment. Until now,
Grätz, Klaus-Wilhelm +5 more
core
Osteonecrosis of the jaws in patients assuming oral bisphosphonates for osteoporosis: A retrospective multi-hospital-based study of 87 Italian cases [PDF]
BACKGROUND: Bisphosphonates (BPs) are currently the chief drugs for the prevention/treatment of osteoporosis; one of their adverse effects is the osteonecrosis of the jaw (BRONJ).
CAMPISI, Giuseppina +11 more
core +1 more source
Osteonecrosis of the jaw in a patient under treatment of osteoporosis with oral bisphosphonate
Although uncommon in patients under oral therapy, bisphosphonate-related osteonecrosis of the jaw (BRONJ) can be a very severe issue. Early intervention with surgical resection should be the preferable method of treating any stage of the disease ...
Marília A. Figueiredo +2 more
doaj

