Results 171 to 180 of about 98,296 (378)

A somatic multiple myeloma mutation unravels a mechanism of oligomerization‐mediated product inhibition in GGPPS

The FEBS Journal, EarlyView.
Geranylgeranyl diphosphate synthase (GGPPS) plays a key role in multiple myeloma biology. Using crystallography, mass spectrometry, and fluorescence spectroscopy, this study shows that a somatic multiple myeloma cell line mutation destabilizes inter‐dimer interactions, resulting in increased GGPPS activity by facilitating product releas.
Ruba Yehia, Jasmína Mária Portašiková, Rut Mor Yosef, Benny Da'adoosh, Alan Kádek, Petr Man, Moshe Giladi, Yoni Haitin   +7 more
wiley   +1 more source

Bisphosphonates and breast carcinoma [PDF]

, 2000
Allan Lipton
openalex   +1 more source

Outcome of Long‐Term Bisphosphonate Therapy in McCune‐Albright Syndrome and Polyostotic Fibrous Dysplasia

Journal of Bone and Mineral Research, 2017
B. Majoor, N. Appelman‐Dijkstra, M. Fiocco, M. V. D. van de Sande, P. Dijkstra, N. Hamdy   +5 more
semanticscholar   +1 more source

Major revision version 13.0 of the European AIDS Clinical Society guidelines 2025

HIV Medicine, EarlyView.
Abstract Background The European AIDS Clinical Society (EACS) guidelines were revised for the 21st time in 2025, with updates covering all aspects of HIV care. Key Points of the Guidelines Update The structure of the guidelines has been reorganized into two parts: Part I focuses on the management and prevention of HIV and related infections, and Part ...
Juan Ambrosioni, Laura I. Levi, Jasmini Alagaratnam, Abiu Sempere, Andrea Mastrangelo, Paolo Paioni, Cristina Mussini, Catia Marzolini, Susanne Dam Nielsen, Charles Béguelin, Steven Welch, Anna Koval, Luis Mendao, Alasdair Bamford, Alexandra Calmy, Giovanni Guaraldi, Cristiana Oprea, Esteban Martínez, Jürgen K. Rockstroh, The EACS Governing Board   +19 more
wiley   +1 more source

Phosphate depletion in the rat: Effect of bisphosphonates and the calcemic response to PTH

, 1999
Aquiles Jara, Elizabeth Lee, Deborah J. Stauber, Farhad Moatamed, Arnold J. Felsenfeld, Charles R. Kleeman   +5 more
openalex   +1 more source

Intermittent Inhibition of Dentin Mineralization of Rat Incisors under Continual Infusion of 1-Hydroxyethylidene-1,1-Bisphosphonate(HEBP) Using a Subcutaneous Mini Osmotic Pump.

, 1999
Hideo Sakai, Yoshiro Takano, Keiichi Ohya, Norimasa Kurosaki   +3 more
openalex   +2 more sources

In Vivo Effects of Bisphosphonates on the Osteoclast Mevalonate Pathway [PDF]

, 2000
J. E. Fisher
openalex   +1 more source

Accuracy of Robotic Computer‐Assisted Implant Surgery Combined With Transcrestal Sinus Floor Elevation for Single‐Tooth Implants: A Retrospective Case Series

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To evaluate the accuracy and safety of robotic computer‐assisted implant surgery (r‐CAIS) for transcrestal sinus floor elevation (TSFE) in single‐tooth implant placement. Materials and Methods In this retrospective case series, we assessed the positional accuracy of r‐CAIS combined with TSFE in the posterior maxilla.
Jieyong Jia, Liangzhi Du, Longlong He, Zhe Li, Yuncong Li, Chengpeng Lv   +5 more
wiley   +1 more source

Repeated vertebral augmentation for new vertebral compression fractures of postvertebral augmentation patients: a nationwide cohort study

Clinical Interventions in Aging, 2015
Cheng-Loong Liang,1 Hao-Kwan Wang,1 Fei-Kai Syu,2 Kuo-Wei Wang,1 Kang Lu,1 Po-Chou Liliang1 1Department of Neurosurgery, E-Da Hospital, I-Shou University, Kaohsiung City, Taiwan; 2Department of Pharmacy, China Medical University Hospital, Taichung City,
Liang CL, Wang HK, Syu FK, Wang KW, Lu K, Liliang PC   +5 more
doaj  

The potent bisphosphonate ibandronate does not induce myeloma cell apoptosis in a murine model of established multiple myeloma [PDF]

, 2000
C M Shipman, Karin Vanderkerken, Michael J. Rogers, J M Lippitt, Kewal Asosingh, D. E. Hughes, R.G.G. Russell, Peter I. Croucher   +7 more
openalex   +1 more source