Results 161 to 170 of about 34,873 (303)

Radiomics Analysis for Predicting Medication‐Related Osteonecrosis of the Jaw Using Computed Tomography

open access: yesOral Diseases, EarlyView.
ABSTRACT Objectives To determine whether pretreatment radiomics can predict medication‐related osteonecrosis of the jaw (MRONJ). Methods Patients with mandibular MRONJ at Hiroshima University Hospital (2009–2024) who underwent MDCT before initiating bone resorption inhibitors were retrospectively identified. Records from 2009 to 2020 were also reviewed
Masaru Konishi
wiley   +1 more source

Sequential Anabolic and Antiresorptive Treatment Promotes Medication‐Related Osteonecrosis of the Jaw in Mice

open access: yesOral Diseases, EarlyView.
ABSTRACT Objective To investigate the effects of sequential administration of romosozumab and denosumab on post‐extraction socket healing and osteonecrosis development in a murine tooth extraction model. Methods Forty female mice were randomly assigned to four groups: control (Ctrl), romosozumab (Rm), denosumab (Dmab), and sequential romosozumab ...
Seo‐Yeong An   +3 more
wiley   +1 more source

Can Knee Arthroscopy Be Considered Entirely Safe for Patients Over 50 Years Old With no Risk of Osteonecrosis? Case Series and Literature Review on Post‐Artrhoscopy Osteonecrosis of the Knee (PAONK)

open access: yesOrthopaedic Surgery, Volume 17, Issue 5, Page 1378-1388, May 2025.
Post‐arthroscopy osteonecrosis is a rare complication occurring in 0.82% of cases, primarily affecting patients over 50 with degenerative meniscal tears. Early detection through MRI and conservative treatment, including bisphosphonates and weight‐bearing avoidance, proved effective in most cases, while some required surgical intervention.
Panagiotis Ntagiopoulos   +9 more
wiley   +1 more source

Breaking the Debilitating Cycle: Pathophysiology, Assessment, and Multimodal Intervention of Secondary Debilitation After Hip Fracture in Older Adults—A Narrative Review

open access: yesOrthopaedic Surgery, EarlyView.
This article provides a comprehensive overview of the pathophysiological mechanisms underlying “secondary debilitation after hip fracture,” discusses the clinical application of risk assessment tools, and presents a phased, stepwise intervention strategy aimed at interrupting the “vicious cycle.” ABSTRACT Hip fractures pose a serious threat to the ...
Wenyang Xu   +4 more
wiley   +1 more source

Multilevel Revision Percutaneous Vertebroplasty in Elderly Patients With Osteoporotic Thoracolumbar Fractures: A Retrospective Cohort Study

open access: yesOrthopaedic Surgery, EarlyView.
Multilevel revision percutaneous vertebroplasty (three or four levels) provided substantial and durable pain relief and functional improvement in elderly patients with osteoporotic thoracolumbar fractures, without increased complication rates. These findings support revision PVP as a safe and effective minimally invasive option for frail patients with ...
Stylianos Kapetanakis   +9 more
wiley   +1 more source

Oral bisphosphonates and risk of incident osteoarthritis in individuals with osteoporosis: a target trial emulation. [PDF]

open access: yesRMD Open
Hatano M   +7 more
europepmc   +1 more source

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