The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag +6 more
wiley +1 more source
In Individuals with Osteogenesis Imperfecta, Cephalometric Findings Suggest that Bisphosphonate Therapy May Improve Craniofacial Growth. [PDF]
Tuurala H +3 more
europepmc +1 more source
Thirty Years of Autologous Platelet Concentrates: From Platelet‐Rich Plasma to Platelet‐Rich Fibrin
This review highlights the 30 years of evolution of APCs, with a focus on their clinical applications and recent technological advancements. ABSTRACT Nearly three decades have now passed since autologous platelet concentrates (APCs) were introduced into clinical practice.
Richard J. Miron +7 more
wiley +1 more source
Bisphosphonates as a Tacrolimus-Sparing Strategy in Kidney Transplantation: Insights from a Retrospective Analysis. [PDF]
Koh HB +12 more
europepmc +1 more source
This randomized controlled trial evaluated the efficacy of demineralized dentin graft (DDG) combined with injectable platelet‐rich fibrin (I‐PRF) and metronidazole (MTZ) versus DDG with or without I‐PRF in alveolar ridge preservation (ARP) of infected extraction sockets.
Mohamed Talaat Elbehwashy +4 more
wiley +1 more source
Macrophage Phenotype Alterations in Treated Periodontitis Patients Suggest a Pro‐Inflammatory Bias
Monocyte‐derived macrophages from successfully treated stage III periodontitis patients show a persistent skewing toward an M1‐like pro‐inflammatory phenotype across polarization conditions, suggesting that immune dysregulation may persist despite clinical periodontal stability.
Mariane Cristina Sloniak +5 more
wiley +1 more source
Fanconi Syndrome After a Single Exposure to Intravenous Zoledronic Acid. [PDF]
Deb R, Elboghdady M, Shrestha A.
europepmc +1 more source
ABSTRACT Introduction Medication‐Related Osteonecrosis of the Jaw (MRONJ) is a severe adverse effect of antiresorptive and antiangiogenic treatment, primarily in osteoporotic and oncologic patients. The disease is characterized by persistent jawbone necrosis that results in significant impairment of the quality of life of involved patients.
Omar Ghanaiem +2 more
wiley +1 more source
Reality of Osteoporosis in Primary Healthcare: An Observational Study in a Portuguese Local Health Unit. [PDF]
Pinto N +10 more
europepmc +1 more source
MRONJ Risk Related to Dental Implants in Osteoporosis Treated With Denosumab: A Systematic Review
ABSTRACT Objectives The aim of this systematic review was to assess the impact of dental implants in osteoporotic patients undergoing treatment with denosumab on MRONJ development, considering both implant surgery‐triggered osteonecrosis (ISTO) and implant presence‐triggered osteonecrosis (IPTO).
Rebheca Maria Pereira Santos +4 more
wiley +1 more source

