Positive predictive values of the coding for bisphosphonate therapy among cancer patients in the Danish National Patient Registry [PDF]
Clinical Epidemiology, 2012 Malene Schou Nielsson,1 Rune Erichsen,1 Trine Frøslev,1 Aliki Taylor,2 John Acquavella,2 Vera Ehrenstein11Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark; 2Center for Observational Research International, Amgen
Nielsson MS +5 more
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Bisphosphonate conjugation for bone specific drug targeting [PDF]
Bone Reports, 2018 Bones provide essential functions and are sites of unique biochemistry and specialized cells, but can also be sites of disease. The treatment of bone disorders and neoplasia has presented difficulties in the past, and improved delivery of drugs to bone ...
Kristen B. Farrell +3 more
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Regioselective ester cleavage during the preparation of bisphosphonate methacrylate monomers [PDF]
Beilstein Journal of Organic Chemistry, 2011 New functional monomers bearing a methacrylate, a bisphosphonate function and, for most, an internal carboxylate group, were prepared for incorporation into copolymers with adhesive or anticorrosive properties.
Kamel Chougrani +3 more
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Bilateral Bisphosphonate-related Atypical Femoral Neck Fracture in a Patient with Familial Mediterranean Fever: A Case Report [PDF]
, 2022 The authors present a rare case of bilateral bisphosphonate-related femoral neck fracture in a patient with Familial Mediterranean fever. Chronic subclinical inflammation that continues in the attack-free period is thought to cause osteopenia ...
Sibel Balıkçı +1 more
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Bisphosphonate-Based Hydrogel with pH-Responsive Minocycline Release Inhibits Microglia/Macrophages of M1 Polarization for Spinal Cord Injury Therapy [PDF]
After spinal cord injury (SCI), the persistent presence of pro-inflammatory microglia/macrophages (M1 phenotype) in injury lesion is one of the major reasons for inducing neuron damage and preventing neurological function recovery.
Yajun Li (240938) +9 more
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Comparison of a Novel Bisphosphonate Prodrug and Zoledronic Acid in the Induction of Cytotoxicity in Human Vγ2Vδ2 T Cells [PDF]
, 2020 Increasing attention has been paid to human γδ T cells expressing Vγ2Vδ2 T cell receptor (also termed Vγ9Vδ2) in the field of cancer immunotherapy.
Senju, Hiroaki +13 more
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Long-term treatment with bisphosphonates and their safety in postmenopausal osteoporosis [PDF]
, 2010 Bisphosphonates are the leading drugs for the treatment of osteoporosis. In randomized controlled trials (RCTs), alendronate, risedronate, and zoledronate have shown to reduce the risk of vertebral, nonvertebral, and hip fractures, whereas RCTs with ...
Graham Russell +8 more
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Bisphosphonates for osteoarthritis [PDF]
Arthritis Research & Therapy, 2011 Synovitis and subchondral bone turnover are associated with pain in osteoarthritis. Bisphosphonates provide tools for investigating these pathogenic mechanisms and also may have therapeutic potential. Translating preclinical findings into new treatments for human osteoarthritis requires a critical appraisal and refinement of animal models ...
Walsh, David A, Chapman, Victoria
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Dose-Intensity of Bisphosphonates and the Risk of Osteonecrosis of the Jaw in Osteoporosis Patients
Frontiers in Pharmacology, 2018 Objective: To examine the incidence rates and association between dose-intensity, stratified by exposure duration, of bisphosphonates and the risk of osteonecrosis of the jaw among Korean osteoporotic patients older than 50 years.
Sung-mok Jung +2 more
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Drugs in Context, 2020 Background: On stopping bisphosphonate treatment, bone resorption may increase before evidence of a decrease in bone density. Offset of bisphosphonate effect may therefore be monitored by measuring C-terminal telopeptide (CTX) following long-term ...
Louise Statham +2 more
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