Results 11 to 20 of about 34,707 (260)

Can bone turnover markers help to define the suitability and duration of bisphosphonate drug holidays?

Drugs in Context, 2020
Background: On stopping bisphosphonate treatment, bone resorption may increase before evidence of a decrease in bone density. Offset of bisphosphonate effect may therefore be monitored by measuring C-terminal telopeptide (CTX) following long-term ...
Louise Statham, Sharon Abdy, Terry J Aspray   +2 more
doaj   +1 more source

Dose-Intensity of Bisphosphonates and the Risk of Osteonecrosis of the Jaw in Osteoporosis Patients

Frontiers in Pharmacology, 2018
Objective: To examine the incidence rates and association between dose-intensity, stratified by exposure duration, of bisphosphonates and the risk of osteonecrosis of the jaw among Korean osteoporotic patients older than 50 years.
Sung-mok Jung, Sujeong Han, Hye-Young Kwon   +2 more
doaj   +1 more source

Association between bisphosphonate use and COVID-19 related outcomes

eLife, 2023
Background: Although there are several efficacious vaccines against COVID-19, vaccination rates in many regions around the world remain insufficient to prevent continued high disease burden and emergence of viral variants.
Jeffrey Thompson, Yidi Wang, Tobias Dreischulte, Olga Barreiro, Rodrigo J Gonzalez, Pavel Hanč, Colette Matysiak, Harold R Neely, Marietta Rottenkolber, Thomas Haskell, Stefan Endres, Ulrich H von Andrian   +11 more
doaj   +1 more source

Questionnaire about Occurrence and Condition of Bisphosphonate-Related Osteonecrosis of the Jaw [PDF]

, 2010
The purpose of this study was to survey the occurrence and condition of bisphosphonate-related osteonecrosis of the jaw (BRONJ). A questionnaire inquiring about clinical experience and the condition of patientswith BRONJ was sent to 11 departments of ...
鎌田, 孝広, 栗田, 浩, 盛岡, 昌史   +2 more
core   +1 more source

Medication‐related osteonecrosis of the jaw leading to sepsis in a patient with rheumatoid arthritis: A case report and clinical implications

Clinical Case Reports, 2023
Key Clinical Message Chronic use of bisphosphonates, in combination with immunosuppressive therapy, increases the risk of jaw osteonecrosis. When sepsis occurs in patients receiving bisphosphonate, osteonecrosis of the jaw should be considered a ...
Kazuhiko Iwasaki, Akihito Okazaki
doaj   +1 more source

Effect of bisphosphonate on temporomandibular joint in osteopenia-induced rats by botulinum toxin A injection on masticatory muscle: a preliminary study

Maxillofacial Plastic and Reconstructive Surgery, 2019
Background Botulinum toxin injection on the masticatory muscle induces the osteopenic condition on the ipsilateral condyle. Bisphosphonate suppresses bone resorption and is used to treat osteopenic or osteoporotic condition.
Jae-Young Kim, Dae-Hoon Kim, Hyo-Won Jang, Kwang-Ho Park, Jong-Ki Huh   +4 more
doaj   +1 more source

Bilateral Bisphosphonate-related Atypical Femoral Neck Fracture in a Patient with Familial Mediterranean Fever: A Case Report

, 2022
The authors present a rare case of bilateral bisphosphonate-related femoral neck fracture in a patient with Familial Mediterranean fever. Chronic subclinical inflammation that continues in the attack-free period is thought to cause osteopenia ...
Sibel Balıkçı, Bilinç Doğruöz Karatekin   +1 more
core   +1 more source

Can Anti-Tumor Necrosis Factor Agents Be Discontinued in Patients with Inflammatory Bowel Disease?

Gut and Liver, 2021
Background/Aims: Bisphosphonates are increasingly recognized for their anti-neoplastic properties, which are the result of their action on the mevalonate pathway.
Jihye Park, Jae Hee Cheon
doaj   +1 more source

Bisphosphonate-Based Hydrogel with pH-Responsive Minocycline Release Inhibits Microglia/Macrophages of M1 Polarization for Spinal Cord Injury Therapy

After spinal cord injury (SCI), the persistent presence of pro-inflammatory microglia/macrophages (M1 phenotype) in injury lesion is one of the major reasons for inducing neuron damage and preventing neurological function recovery.
Yajun Li (240938), Jianwu Dai (122949), Liyang Shi (1676794), Ya Li (194567), Shan Pei (17755256), Lili Wang (104605), Ziqiang Wang (1628740), Ranxi Chen (17719063), Yuyun Liang (13102332), Can Zhang (56016)   +9 more
core   +5 more sources

Is the Long-term Disease Course of Elderly-Onset Ulcerative Colitis Different from That of Non-Elderly-Onset Ulcerative Colitis?

Gut and Liver, 2021
Background/Aims: Bisphosphonates are increasingly recognized for their anti-neoplastic properties, which are the result of their action on the mevalonate pathway.
Jin Wook Lee, Eun Soo Kim
doaj   +1 more source