Results 51 to 60 of about 34,873 (303)
Arthroplasty Today, 2016 We present a case of a bisphosphonate-related femur fracture in an elderly woman, who failed treatment with both cephalomedullary nail and proximal femoral locking plate, leading to successful treatment with total hip arthroplasty.
Rishabh G. Jethanandani, BSE +4 more
doaj +1 more source
Advanced Science, EarlyView.Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu +9 more
wiley +1 more source
Frontiers in Surgery, 2023 The risk of bisphosphonate (BP)-associated atypical femur fracture (AFF) has markedly increased over recent decades due to suppression of bone turnover, accumulation of structural micro-damage and reduction of bone remodeling consequent to long-term BP ...
Jianpeng Gao +9 more
doaj +1 more source
Advanced Science, EarlyView.GCs reduce Parkin, leading to ACSL4 accumulation and PUFA‐phospholipid‐driven ferroptosis in BMSCs, which impairs osteogenesis and promotes adipogenesis, causing GIOP. Parkin restoration (via OE‐Parkin or Parkin‐LNP@DSS6) ubiquitinates and degrades ACSL4, inhibiting ferroptosis, rescuing bone formation, and rescues GIOP bone loss.
Li‐jiang Han +16 more
wiley +1 more source
Bisphosphonate-related bilateral atypical femoral fractures : be aware and beware [PDF]
, 2011 Although bisphosphonates have a well established therapeutic role in the prevention of osteoporosis-related fractures, several reports published over the past 5-6 years suggest a possible causative relationship between long-term use of bisphosphonates ...
Depasquale, Ruben +2 more
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Modified Titanium Dental Implants: The Current Progress of Soft‐Tissue Integration Methods
Advanced NanoBiomed Research, EarlyView.Dental implants are an established solution for tooth loss, yet achieving soft tissue integration (STI) around the transmucosal region remains a challenge. The natural tooth–gingiva interface is poorly replicated on titanium implants. This review explores surface modification strategies, ranging from surface chemistry and topography to biological ...
Daniel De Maria +5 more
wiley +1 more source
Development of colloids for cell and tissue targeting: bisphosphonate-functionalized gold nanoparticles for the investigation of bone targeting [PDF]
, 2010 Gold nanoparticles (GNPs) possess a great potential as model systems for the investigation of nanoparticulate drug delivery due to their ease of production, low toxicity and also the high stability of the noble metal in biological fluids.
Zayed, Gamal
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Short-term Bisphosphonate use associated stress fractures [PDF]
, 2022 Introduction: Long-term bisphosphonate use has been linked to an increased risk of pathological neck of femur fractures. Case report: We write concerning a patient who presented with the left hip pain following a low impact fall, which was diagnosed as ...
Anakwe, Raymond +2 more
core +1 more source
Clinical and CBCT assessment of role of bisphosphonate on osteotomy site and implant surface
Journal of Pharmacy and Bioallied SciencesObjectives: To assess the role of bisphosphonate on osteotomy site and implant surface. Materials and Methods: Twenty patients with adequate width and height of edentulous space and a single missing posterior tooth between the ages of 25 and 55 were ...
Amit Singh +6 more
doaj +1 more source
Clinical Interventions in Aging, 2021 Hao-Ran Zhang,1,* Yun-Long Zhao,1,* Rui-Qi Qiao,2 Ji-Kai Li,2 Yong-Cheng Hu1 1Department of Bone Tumor, Tianjin Hospital, Tianjin, People’s Republic of China; 2Graduate School, Tianjin Medical University, Tianjin, People’s Republic of China&ast ...
Zhang HR, Zhao YL, Qiao RQ, Li JK, Hu YC
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