Results 81 to 90 of about 98,296 (378)
Anti-Tumor Activity and Immunotherapeutic Potential of a Bisphosphonate Prodrug
Scientific Reports, 2017 Bisphosphonates have benefits in breast cancer and multiple myeloma patients and have been used with adoptive immunotherapy with γδ T cells expressing Vγ2 Vδ2 TCRs. Although treatment with γδ T cells is safe, it has shown limited efficacy.
Yoshimasa Tanaka +9 more
semanticscholar +1 more source
Advanced Science, EarlyView.Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong +6 more
wiley +1 more source
Coping with complexity: working beyond the guidelines for patients with multimorbidities [PDF]
, 2015 Primary care physicians believe they are delivering evidence-based care, understanding that adherence to evidence-based clinical guidelines results in tangible benefits in the populations for which they were developed.
Treadwell, Julian
core +3 more sources
British Journal of Clinical Pharmacology, EarlyView.People accessing aged care services are increasingly older and often experience multimorbidity and polypharmacy, which puts them at risk of medication‐related harm. Quality indicators (QIs) can assist with monitoring, benchmarking and informing initiatives to reduce medication‐related harm.
Daria S. Gutteridge +20 more
wiley +1 more source
A review on the prevention of inflammatory periimplant diseases [PDF]
, 2019 Background: An impressive number of dental implants are inserted worldwide. Evolution in dental implants and simplification of surgical techniques allowed a significant increase in the number of dentists involved in implant surgery.
Di Nardo, D. +3 more
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims “Triple whammy” (TW) refers to the concomitant use of diuretics, renin‐angiotensin‐aldosterone system inhibitors (RAASI) and non‐steroidal anti‐inflammatory drugs (NSAIDs). The aim of this article is to analyse the association between TW exposure and acute kidney injury (AKI), among other morbi‐mortality outcomes.
Dulce María Calvo +4 more
wiley +1 more source
Clinical Advances in Periodontics, EarlyView.ABSTRACT Background To evaluate the efficacy and long‐term clinical outcomes of the one‐stage procedure for covering isolated deep gingival recessions (GRs) in the mandibular anterior region employing a laterally positioned flap (LPF) with a connective tissue graft (CTG), with a retrospective case series.
Lucrezia Parma‐Benfenati +1 more
wiley +1 more source
Role of Teriparatide in Medication-Related Osteonecrosis of the Jaws (MRONJ)
Dentistry Journal, 2016 While the optimal treatment concept of medication-related osteonecrosis of the jaws (MRONJ) is still in debate, several adjunct therapies have been introduced.
Yong-Dae Kwon, Deog-Yoon Kim
doaj +1 more source
Antioxidants, 2020 Bisphosphonates (BPs) are classified into two groups, according to their side chain structures, as nitrogen-containing BPs (NBPs) and non-nitrogen-containing BPs (non-NBPs).
Keiko Suzuki +6 more
doaj +1 more source
Monitoring Receptor Clustering by Aggregation‐Induced Emission
ChemPlusChem, EarlyView.Receptor clustering induced by molecular recognition: AIE‐functionalized bisphosphonate receptors are embedded in a lipid bilayer. Upon addition of a cationic messenger, they undergo dimerization and send out a fluorescence signal. This study introduces a simple signal transduction system that mimics the receptor tyrosine kinase mechanism by employing ...
Robert Bekus +4 more
wiley +1 more source