Results 51 to 60 of about 561,868 (383)
Leukemia, 2017 The efficacy of early bispecific antibodies redirecting T-cells to eradicate cancer cells was partly limited because of suboptimal effector cell engagement.1 More efficient T-cell activation has been obtained with single-chain variable fragment (scFv ...
C. Correnti +10 more
semanticscholar +1 more source
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren +16 more
wiley +1 more source
, 2016 Is originalism toothless? Richard Posner seems to think so. He writes that repeated theorizing by intelligent originalists, one of us happily included, has rendered the theory incoherent and capable of supporting almost any result.
Baude, William, Sachs, Stephen E.
core +1 more source
JAMA: The Journal of the American Medical Association, 1883 In the article on the Medical and Surgical Practice of the Aborigines of America, contributed by F. Andros, M.D., and published in your issue of Aug. 4, it is stated that some tribes apply the bruised wild onion for the stings of bees and wasps. I am not aware that any similar practice has been recommended in the literature of our profession, though ...
openaire +2 more sources
Surgical management of facial dog bite trauma: A contemporary perspective and review
World Journal of Otorhinolaryngology-Head and Neck Surgery, 2023 Objective To perform a review evaluating management of and complications stemming from dog bite trauma sustained to the head and neck over the past decade. Data Sources PubMed and Cochrane Library.
Tiffany Chen +6 more
doaj +1 more source
CINs of the cytoplasm: dissecting dsRNA signaling in chromosomal instability
Molecular Oncology, EarlyView.Micronuclei, formed during cell division in chromosomal instability settings, rupture and lead to the accumulation of immunogenic double‐stranded RNA in the cytoplasm, activating MAVS‐dependent interferon signaling and innate antitumor immunity.
Aglaia Skolariki +2 more
wiley +1 more source
Tarantula Bite in Iran, a Letter to the Editor
Archives of Academic Emergency Medicine, 2018 I read with great interest the case report titled “Periumbilical pain with radiation to both legs following tarantula bite; a case report†published in Emergency journal. Tarantula spiders are not medically important except for some very limited ...
Hossein Sanaei Zadeh
doaj +1 more source
Journal of Oral Medicine and Oral Surgery, 2020 Introduction: The treatment of facial wounds by human bites is difficult, especially in under-developed countries. We aimed to distinguish the epidemiological and clinical aspects to describe the therapeutic methods and evaluate their effectiveness ...
Zegbeh-N'guessan Eric Kouassi +5 more
doaj +1 more source
Parasites & Vectors, 2016 Leishmania spp., the causative agents of leishmaniasis, are intracellular parasites, transmitted to humans via the bite of their sand fly vectors. Once inoculated, the promastigotes are exposed to the dermis, which is composed of extracellular matrix ...
J. D. de Menezes +2 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui +5 more
wiley +1 more source