Results 51 to 60 of about 256,840 (345)

Epidemiology of dog bites in Patna: A cross sectional study

open access: yesIndian Journal of Community and Family Medicine, 2015
Background: Dogs bite more than 4.7 million people a globally. India has the highest rate of human rabies in the world, primarily because of stray dogs, whose number has largely increased since 2001.
N Agarwal   +6 more
doaj   +1 more source

TREX1, a predator for treating MSI‐H tumors?

open access: yesMolecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya   +2 more
wiley   +1 more source

Real-Time Surveillance of Dog Bite Incidence in Islamabad: A Cross-Sectional Study from December 2019 to July 2020

open access: yesZoonotic Diseases, 2023
Rabies is a neglected viral zoonotic disease with an almost 100% fatality rate. A pilot project was initiated by the National Institute of Health (NIH), Islamabad, in collaboration with Health Security Partners (HSP) to establish a real-time dog bite ...
Shafiq ur Rehman   +9 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Direction of association between bite wounds and Mycobacterium bovis infection in badgers: implications for transmission. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND: Badgers are involved in the transmission to cattle of bovine tuberculosis (TB), a serious problem for the UK farming industry. Cross-sectional studies have shown an association between bite wounds and TB infection in badgers which may have ...
Helen E Jenkins   +2 more
doaj   +1 more source

The effect of herbage mass and allowance on herbage intake, diet composition and ingestive behaviour of dairy cows [PDF]

open access: yes, 2004
peer-reviewedAn experiment was conducted to examine the effects of herbage mass [HM, based on regrowth intervals of 35 (T) and 21 (S) days] and herbage allowance [HA, 20.2 (H) and 12.7 (L) kg organic matter (OM)/cow] on herbage OM intake (OMI), dietary
Dillon, Pat, Stakelum, G.
core  

Understanding uncertainty in temperature effects on vector-borne disease: A Bayesian approach [PDF]

open access: yes, 2014
Extrinsic environmental factors influence the distribution and population dynamics of many organisms, including insects that are of concern for human health and agriculture.
Amy McNally   +18 more
core   +3 more sources

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

Ingestive behavior of sheep in Panicum and Brachiaria pastures in dry season

open access: yesBioscience Journal, 2016
The ingestive behavior of sheep supplemented with concentrate in Brachiaria brizantha and Panicum maximum pastures were evaluated during the dry season. Twenty four male sheep of ½ Santa Inês x ½ undefined breed genotypes were used. The treatments were
Larissa Fernanda do Nascimento Silva   +6 more
doaj   +3 more sources

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