Results 1 to 10 of about 391,698 (301)
Modulation of STAT signaling by STAT-interacting proteins [PDF]
Oncogene, 2000 STATs (signal transducer and activator of transcription) play important roles in numerous cellular processes including immune responses, cell growth and differentiation, cell survival and apoptosis, and oncogenesis. In contrast to many other cellular signaling cascades, the STAT pathway is direct: STATs bind to receptors at the cell surface and ...
K Shuai
exaly +3 more sources
THE EFFECT OF B. subtillis ІМV B-7724 LECTIN ON FUNCTIONAL ACTIVITY OF THE MAIN EFFECTORS OF ANTITUMOR IMMUNITY OF INTACT MICE [PDF]
Biotechnologia Acta, 2022 Aim. The purpose of the study was to evaluate the effect of B. subtilis IMV B-7724 lectin on the functional activity of macrophages (Mph) and natural killer cells (NK) of intact Balb/c mice. Materials and Methods.
N.I. Fedosova +5 more
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Prezumţia de nevinovăţie în izvoarele doctrinare și normative din Europa occidentală (sec. XIX-XX) [PDF]
Revista Institutului Naţional de Justiţie, 2023 Valoarea supremă într-un stat este omul, drepturile și libertățile lui, iar recunoașterea, respectarea și apărarea acestor drepturi și libertăți reprezintă obligațiunea de bază a statului.
Vizdoagă Tatiana, Iulia BRIA
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PARTICULARITĂȚILE APLICĂRII NORMELOR DREPTULUI INTERNAȚIONAL ÎN CONTEXTUL CONFLICTULUI TERITORIAL DIN TRANSNISTRIA [PDF]
Moldoscopie, 2020 Subiectul jurisdicției aplicabile în raport cu membrii forțelor armate ale Federației Ruse care staționează pe teritoriul Republicii Moldova este unul actual pentru comunitatea internaţională.
Marcel BENCHECI
doaj +1 more source
Nordisk Välfärdsforskning, 2023 Sammanfattning Den globala nyliberaliseringsprocessen har sedan 1970-talet förändrat villkoren för den ekonomiska politiken. Medan angloamerikanska exempel tidigare legat till grund för teoretiseringar av nyliberaliseringsprocesser, fokuserar den här ...
Erik Thosteman
doaj +1 more source
CONCEPTUALIZAREA TERMENULUI DE DIASPORĂ: ASPECTE TEORETICO-METODOLOGICE [PDF]
Moldoscopie, 2021 În prezentul articol se caracterizează principalele abordări și definiții ale termenului de diasporă. Diaspora apare pe baza grupurilor etnice care locuiesc în afara statelor sale ”titulare”.
Gheorghe MOȘNEAGA
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Oncogene, 2000 Since their discovery as key mediators of cytokine signaling, considerable progress has been made in defining the structure-function relationships of Signal Transducers and Activators of Transcription (STATs). In addition to their central roles in normal cell signaling, recent studies have demonstrated that diverse oncoproteins can activate specific ...
T, Bowman +3 more
openaire +2 more sources
Experimed, 2023 Objective: Impairment of immune cell signaling molecules is involved in diseases pathogenesis. The evaluation of signal transducer and activator of transcription (STAT) 4 and protein inhibitor of activated STAT (PIAS) 2 as well as immunoregulatory role ...
Sina Nabiyi +3 more
doaj +1 more source
Pifu-xingbing zhenliaoxue zazhi, 2023 Objective To investigate the effects of β-estradiol (E2) on the phosphorylation of JAK/STAT, PI3K/AKT signaling pathways and the expression of IL-17A in mouse spleen mononuclear cells treated with IL-36β. Methods The spleens were isolated from female SPF
Shuang LIU +7 more
doaj +1 more source
STAT signaling pathways in immune cells and their associated mechanisms in cancer pathogenesis [PDF]
BioImpactsIntroduction: Signal transducer and activator of transcriptions (STATs) factors as critical proteins in cell signaling regulate diverse biological processes such as differentiation and proliferation of cells.
Sepideh Sohrabi +4 more
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