Results 181 to 190 of about 61,588 (194)

APOBEC3B Signature Mutations Benefit BK Polyomavirus

SSRN Electronic Journal, 2018
BK polyomavirus (BKV) causes nephropathy in kidney transplant recipients (KTRs). The virus has also been implicated as a possible cause of bladder and kidney cancers. Two KTRs who developed BKV nephropathy followed by renal carcinoma both showed a swarm of BKV sequence variants encoding non-silent mutations in surface loops of the viral major coat ...
Alberto Peretti, Eileen M. Geoghegan, Diana V. Pastrana, Sigrun Smola, Pascal Feld, Marlies Sauter, Stefan Lohse, Mayur Ramesh, Efrem S. Lim, David Wang, Cinzia Borgogna, Peter C. FitzGerald, Valery Bliskovsky, Gabriel J. Starrett, Reuben S. Harris, J. Keith Killian, Jack Zhu, Marbin Pineda, Paul S. Meltzer, Renzo Boldorini, Marisa Gariglio, Christopher Buck   +21 more
openaire   +1 more source

Reducing calcineurin inhibitor first for treating BK polyomavirus replication after kidney transplantation: long-term outcomes.

Nephrology, Dialysis and Transplantation, 2018
Background Reducing immunosuppression is the mainstay of treating BK polyomavirus (BKPyV) viraemia after kidney transplantation, but the best approach, efficacy and impact are undefined.
N. Bischof, H. Hirsch, Caroline Wehmeier, P. Amico, M. Dickenmann, P. Hirt-Minkowski, J. Steiger, T. Menter, Hopfer Helmut, S. Schaub   +9 more
semanticscholar   +1 more source

Establishment of COS‐BK cells persistently infected with archetype BK polyomavirus

Microbiology and Immunology
AbstractBK polyomavirus (BKPyV) was the first human polyomavirus to be isolated from an immunosuppressed kidney transplant recipient in 1971. BKPyV reactivation causes BKPyV‐associated nephropathy and hemorrhagic cystitis. However, the mechanisms underlying BKPyV replication remain unclear.
Souichi Nukuzuma, Hiroshi Onogi, Tetsuro Suzuki   +2 more
openaire   +2 more sources

Human Polyomavirus JC and BK Persistent Infection

2007
Primary contact with the human polyomaviruses (HPV) is followed by lifelong persistence of viral DNA in its host. The most prominent organs affected are the kidney, the Central Nervous System (CNS)and the hematopoietic system. Under impairment of immune competence limited activation of virus infection can be followed by prolonged virus multiplication ...
openaire   +2 more sources

Insight Into Current BK Polyomavirus Research Efforts: BK Day Meeting 2024

Transplantation

Tiana A, Walder, Caroline A, Hillenbrand, Hans H, Hirsch, Gabriel J, Starrett, Anthony, Sabulski, Christopher B, Buck, Joshua, Justice, Benjamin L, Laskin, Stella M, Davies, Jason T, Blackard   +9 more
openaire   +2 more sources

Polyomavirus BK in the pathogenesis of bladder cancer.

The Netherlands journal of medicine, 2013
Polyomaviruses are able to drive malignant transformation in rodent models, and have been implicated in the aetiology of a variety of human malignancies. However, the reports on this association in humans are strongly conflicting. Here we describe a renal transplant (RT) recipient with ureteral stenosis against the background of polyomavirus BK (BKV ...
van Aalderen, M. C., Yapici, Ü, van der Pol, J. A., de Reijke, T. M., van Donselaar-van der Pant, K. A. M. I., Florquin, S., Bemelman, F. J., ten Berge, I. J. M.   +7 more
openaire   +2 more sources

Virus-specific T-cell therapy to treat BK polyomavirus infection in bone marrow and solid organ transplant recipients.

Blood Advances, 2020
A. Nelson, Daria Heyenbruch, Jeremy D. Rubinstein, Anthony Sabulski, S. Jodele, S. Thomas, C. Lutzko, Xiang Zhu, T. Leemhuis, J. Cancelas, M. Keller, C. Bollard, P. Hanley, S. Davies, M. Grimley   +14 more
semanticscholar   +1 more source

Assessment of the Banff Working Group classification of definitive BK polyomavirus nephropathy

Transplant International, 2021
J. Kowalewska, Ismail El Moudden, A. Perkowska-Ptasińska, M. Kapp, A. Fogo, Mercury Y. Lin, Alamgir Mirza, D. Troyer, M. Durlik, R. Sandhu, M. Ciszek, D. Dęborska-Materkowska, Danielle Kuczynski, T. McCune   +13 more
semanticscholar   +1 more source

Typische Histologien – BK(Polyomavirus)-Nephropathie

Nieren- und Hochdruckkrankheiten, 2012
M. Büttner, J. Velden, V. Kufer, K. Amann   +3 more
openaire   +1 more source

Viral integration in BK polyomavirus-associated urothelial carcinoma in renal transplant recipients: multistage carcinogenesis revealed by next-generation virome capture sequencing

Oncogene, 2020
Yuchen Wang, Yanna Liu, W. Deng, Fangxiang Fu, Susha Yan, Han Yang, Ru-min Liu, Jian Geng, Jian Xu, Yihan Wu, Junfeng Ma, Jiapeng Zhou, Na Liu, Yu Jin, R. Xia, N. Elias, Richard J Lee, A. Feldman, M. Blute, R. Colvin, Chin-Lee Wu, Y. Miao   +21 more
semanticscholar   +1 more source