Results 191 to 200 of about 10,884 (222)
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Immunosuppression, BK polyomavirus infections, and BK polyomavirus-specific T cells after pediatric kidney transplantation

Pediatric Nephrology, 2019
After kidney transplantation, immunosuppressive therapy increases risk of BK polyomavirus-associated nephropathy (BKPyVAN). Outcomes of BKPyV viremia are various and prognostic markers are missing. The impact of different immunosuppressive regimens on BKPyV infections is currently under discussion.We analyzed immunosuppressive therapy and BKPyV ...
Thurid Ahlenstiel-Grunow, Lars Pape
openaire   +2 more sources

BK Polyomavirus Infection in the Renal Transplant Recipient

Infectious Disease Clinics of North America, 2013
Renal transplant recipients continue to have progressive kidney dysfunction and renal graft loss has been attributed to emerging opportunistic infections, specifically BK virus (BKV). BKV is postulated to be selected by the new potent immunosuppressive medications and to be an important factor in graft failure.
Gayle P, Balba   +2 more
openaire   +2 more sources

BK Polyomavirus Consensus

Clinical Infectious Diseases, 2022
Hans H Hirsch   +2 more
openaire   +2 more sources

Polyomavirus BK in the pathogenesis of bladder cancer.

The Netherlands journal of medicine, 2013
Polyomaviruses are able to drive malignant transformation in rodent models, and have been implicated in the aetiology of a variety of human malignancies. However, the reports on this association in humans are strongly conflicting. Here we describe a renal transplant (RT) recipient with ureteral stenosis against the background of polyomavirus BK (BKV ...
van Aalderen, M. C.   +7 more
openaire   +2 more sources

Polyomavirus BK-Specific Immunity after Kidney Transplantation

Transplantation, 2004
Failure to mount or maintain a protective immune response may influence the development of polyomavirus BK (BKV)-associated nephropathy (PVAN). However, limited data are so far available on BKV-specific immunity after kidney transplantation. BKV-specific cellular immune response was retrospectively analyzed in kidney recipients with or without BKV ...
COMOLI P   +12 more
openaire   +4 more sources

Nephropathy Due to Polyomavirus Type BK

New England Journal of Medicine, 2000
Polyomavirus type BK (BK virus) is a nonenveloped virus with circular, double-stranded DNA that has 70 percent homology with simian virus 40.
Parmjeet S. Randhawa   +1 more
openaire   +1 more source

BK Polyomavirus microRNA in Kidney Transplant Recipient

Transplantation Proceedings
BK polyomavirus-associated nephropathy (PyVAN) remains a serious threat for renal dysfunction and graft loss in kidney transplant recipients on immunosuppressive medication. In this study, a pilot cohort of 16 kidney transplant recipients were recruited of which eight were with significant BKPV viremia (sBKPV) and the rest were controls matched to age,
Rajat Nog   +7 more
openaire   +2 more sources

Establishment of COS‐BK cells persistently infected with archetype BK polyomavirus

Microbiology and Immunology
AbstractBK polyomavirus (BKPyV) was the first human polyomavirus to be isolated from an immunosuppressed kidney transplant recipient in 1971. BKPyV reactivation causes BKPyV‐associated nephropathy and hemorrhagic cystitis. However, the mechanisms underlying BKPyV replication remain unclear.
Souichi Nukuzuma   +2 more
openaire   +2 more sources

Human Polyomavirus JC and BK Persistent Infection

2007
Primary contact with the human polyomaviruses (HPV) is followed by lifelong persistence of viral DNA in its host. The most prominent organs affected are the kidney, the Central Nervous System (CNS)and the hematopoietic system. Under impairment of immune competence limited activation of virus infection can be followed by prolonged virus multiplication ...
openaire   +2 more sources

The in vitro effect of monensin on BK polyomavirus replication.

The new microbiologica, 1995
The in vitro effect of monensin, a linear polyether, on the infection of Vero cells by BK polyomavirus, was investigated. Data reported in this paper showed an inhibition of BK viral replication by monensin as monitored by immunofluorescence and molecular hybridization.
PIETROPAOLO, Valeria Antonietta   +4 more
openaire   +2 more sources

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