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BK Polyomavirus Infection in the Renal Transplant Recipient
Infectious Disease Clinics of North America, 2013Renal transplant recipients continue to have progressive kidney dysfunction and renal graft loss has been attributed to emerging opportunistic infections, specifically BK virus (BKV). BKV is postulated to be selected by the new potent immunosuppressive medications and to be an important factor in graft failure.
Gayle P, Balba +2 more
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Polyomavirus BK in the pathogenesis of bladder cancer.
The Netherlands journal of medicine, 2013Polyomaviruses are able to drive malignant transformation in rodent models, and have been implicated in the aetiology of a variety of human malignancies. However, the reports on this association in humans are strongly conflicting. Here we describe a renal transplant (RT) recipient with ureteral stenosis against the background of polyomavirus BK (BKV ...
van Aalderen, M. C. +7 more
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Polyomavirus BK-Specific Immunity after Kidney Transplantation
Transplantation, 2004Failure to mount or maintain a protective immune response may influence the development of polyomavirus BK (BKV)-associated nephropathy (PVAN). However, limited data are so far available on BKV-specific immunity after kidney transplantation. BKV-specific cellular immune response was retrospectively analyzed in kidney recipients with or without BKV ...
COMOLI P +12 more
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Polyomavirus BK infection in Greek renal transplant recipients
Transplantation Proceedings, 2004BK polyoma virus associated nephropathy is increasingly recognized as an important cause of allograft dysfunction among renal transplant recipients. Herein we present the cases of two renal transplant recipients who developed progressive functional deterioration suspicious for BK polyoma virus involvement.
G, Zavos +7 more
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BK Polyomavirus microRNA in Kidney Transplant Recipient
Transplantation ProceedingsBK polyomavirus-associated nephropathy (PyVAN) remains a serious threat for renal dysfunction and graft loss in kidney transplant recipients on immunosuppressive medication. In this study, a pilot cohort of 16 kidney transplant recipients were recruited of which eight were with significant BKPV viremia (sBKPV) and the rest were controls matched to age,
Rajat Nog +7 more
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Establishment of COS‐BK cells persistently infected with archetype BK polyomavirus
Microbiology and ImmunologyAbstractBK polyomavirus (BKPyV) was the first human polyomavirus to be isolated from an immunosuppressed kidney transplant recipient in 1971. BKPyV reactivation causes BKPyV‐associated nephropathy and hemorrhagic cystitis. However, the mechanisms underlying BKPyV replication remain unclear.
Souichi Nukuzuma +2 more
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Human Polyomavirus JC and BK Persistent Infection
2007Primary contact with the human polyomaviruses (HPV) is followed by lifelong persistence of viral DNA in its host. The most prominent organs affected are the kidney, the Central Nervous System (CNS)and the hematopoietic system. Under impairment of immune competence limited activation of virus infection can be followed by prolonged virus multiplication ...
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Polyomavirus BK and Autoimmunity to Nucleosomes
Graft, 2002Ole Petter Rekvig, Ugo Moens
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